Piotr California Republic

[Bryan Johnson @bryan_johnson]

Cancer runs in my family and about 5-10% of cancer is inherited. So I did a blood test that looked at 71 genes for inherited cancer risk.

All came back negative. I feel lucky.

You can sleep, exercise and eat right for decades, and one late cancer can do you in. Cancer is the second leading cause of death in the US, the first for anyone under 85. More than 1 in 3 of us will be diagnosed. A cancer death costs nearly 15 years of life, on average.

You want to catch cancer early. Breast cancer has a 5 year survival near 100% but caught late, survival drops to about 34%. Colon cancer: 91% versus 16%.

A genetic risk panel won't tell you if you have cancer. It tells you whether you were born holding a bad card, so you can watch the right things, sooner.

So I ran a combined DNA + RNA Panel covering 71 genes tied to inherited cancer risk, with RNA analysis on most. They cover the big hereditary pathways. DNA repair (BRCA1, BRCA2, ATM). Lynch syndrome (MLH1, MSH2). The classic tumor suppressors (TP53, APC, PTEN). The endocrine genes (RET, VHL, MEN1).

DNA shows the spelling of a gene. RNA shows what the cell actually builds from it. Up to 1 in 4 cancer-gene variants are predicted to disrupt splicing, the RNA edit that makes a working protein, and DNA alone often can't tell whether it matters, so it gets flagged "uncertain." Reading the RNA settles a lot of those, and catches broken variants DNA-only tests miss.

My result came back with no pathogenic variants in any of the tested genes, so it looks like I was born lucky.

This doesn't mean it clears cancer risk and it says nothing about the 90 to 95% of cancers that aren't inherited or influenced over a lifetime from age, environment, and luck.

Cancer surveillance is among the least glamorous parts of a longevity stack. It's also the most underrated.

The name of this test is Invitae Multi-Cancer Panel.

[Piotr California Republic @Piotr73001]

@siimland Siim Land has a Bryan Johnson complex. Bryan Johnson is better in every way and has done 100 times more for people. Siim is the kind of biohacker who overdosed on vitamin B6 because he didn't know you can take magnesium without B6.

[Piotr California Republic @Piotr73001]

@Liathetrader @siimland Czy w Miami na Florydzie nie jest dla Ciebie zbyt wilgotno?

[Piotr California Republic @Piotr73001]

@filipwojda @bryan_johnson @_katetolo Powinieneś prowadzić te badania w Polsce

[Piotr California Republic @Piotr73001]

@natxwang @bryan_johnson Nie warto lizać waginy i ryzykować, seks też bez całowania

[Piotr California Republic @Piotr73001]

@EfromAus @bryan_johnson Nie warto lizać waginy, można tylko wkładać węża

[Piotr California Republic @Piotr73001]

@sacredpresence @bryan_johnson Nie warto lizać

[Piotr California Republic @Piotr73001]

@diana_dukic @bryan_johnson Nigdy nie liże cipki, wsadzam tam tylko mojego węża

[Piotr California Republic @Piotr73001]

@zenbiz1 @bryan_johnson Tak bo cipki nie wolno dotykać językiem

[Piotr California Republic @Piotr73001]

@drmegroekle @bryan_johnson Nie warto z Tobą uprawiać seksu

[Piotr California Republic @Piotr73001]

@rafal_zaorski Tak wyznawcy bronili swojego Boga Rafała:) Gdzie teraz jesteście?
https://t.co/BP3bkuQNGc

[Piotr California Republic @Piotr73001]

@PawelDSM Ale jak ten żonaty pracownik na początku zaczął uprawiać seks z tą atrakcyjną kobietą to było dobrze:)
Widocznie to był słaby zawodnik i nie starczyło mu sił na żonę i tą kobietę:)

[Paweł Usiądek @PUsiadek]

Im bardziej nauka postępuje, tym trudniej być ateistą.

Spójrzmy na to: najbardziej szczegółowy obraz pojedynczej ludzkiej komórki, jaki kiedykolwiek powstał.

Twoje ciało zawiera 37 bilionów z nich.

To boska inżynieria.

[Piotr California Republic @Piotr73001]

@GdzieJest15M Tak się broni swojego Boga Zaorskiego
https://t.co/w2kgBW3S91

[Piotr California Republic @Piotr73001]

@PrzemekGoldmann @GdzieJest15M Tylko, że Suszek musiał potem stracić za to życie bo nawet majątku Suszka zabrakło jak dług eksplodował do około 80 milionów

[Siim Land @siimland]

Bowhead whales live 200+ years with low cancer risk.

A new study discovered that it might have to do with their powerful DNA repair abilities.

Most animals prevent cancer by detecting DNA damage and killing the cell (apoptosis) or stopping its growth (senescence).

Bowhead whales don't kill the damaged cells; instead, they repair them before mutations occur.

In the study, scientists put one of the key repair proteins called CIRBP into human cells, and their DNA repair improved, and fewer mutations occurred after DNA damage.

For humans, it means that increasing DNA repair and precise repair mechanisms could be a factor for longevity

Full video: https://t.co/7OBP3ZOBaD

Full study: https://t.co/NtJ98twTAe

[Piotr California Republic @Piotr73001]

@GdzieJest15M @AliorBankSA To jest tylko fake pod to, że całą kasę musiał spłacać dla Mafii od Suszka za ukradzione bitcoiny. Teraz musiał jakiś wytłumaczyć, że nie ma pieniędzy nawet ze sprzedaży Apartamentu na złotej 44 bo wszystko musiał oddać na długi

[Piotr California Republic @Piotr73001]

@GdzieJest15M @AliorBankSA https://t.co/GnBQPdhUzS

Tak wyznawcy bronili swojego Boga spekulacji

[Piotr California Republic @Piotr73001]

@GdzieJest15M Tak pucybuty Zaora bronili jak Boga
https://t.co/ePfZKKQhYf

[Piotr California Republic @Piotr73001]

@GdzieJest15M Nie udawajcie obrońcy Zaora, że nie widzieliście
https://t.co/7pWjxMp43C