The Pratt Group

News from our organic free radical chemistry research group. Engaged in synthesis, mechanistic studies and applications in medicine and beyond.

[J. Am. Chem. Soc. @J_A_C_S]

Intramolecular Hydrogen Atom Transfer Enables Hydroperoxyl Radical Formation during the Peroxidation of Unsaturated Lipids | Journal of the American Chemical Society @PrattGroup
@uOttawaScience https://t.co/1qMiB7tbEN

[uOttawa Science @uOttawaScience]

Congratulations to Robert W. Boyd and Derek A. Pratt from the Faculty of Science for this outstanding recognition!

[The Pratt Group @PrattGroup]

Platinum(II)-based cytoprotectants? You read that right - platinum is not just for killing cells! Congrats to former undergrad extraordinaire Mike Donohoe on a super effort for his first publication and @adityau1993 for his first paper @J_A_C_S. #ferroptosis @uOttawaResearch

[J. Am. Chem. Soc. @J_A_C_S]

Ligand-Based Radical Reactivity of Metal Thiosemicarbazones Prompts Identification of Platinum(II)-Based Cytoprotectants | Journal of the American Chemical Society @uOttawa #LigandBased #Radical #Reactivity #Metal #Thiosemicarbazones #Pt #Cytoprotectants https://t.co/3DyN1xJk7C

[James Olzmann @OlzmannLab]

Please RT and help us get the word out. Scott Dixon @sjd956 and I are co-organizing the first @FASEBorg #Ferroptosis conference this summer! Awesome line up of speakers and room for additional short talks! Save the date & come join us July 27 - 31, 2025! 🤩https://t.co/VlV9L3kxx1

[TetrahedronSymposium @TetrahedronSymp]

#TETSymp First speakers announced 🎉
Meet with world-class organic chemists at the 2025 Tetrahedron Symposium (Bruges, Belgium, 1-5 July 2025).
Submit your #organicchemistry, bioorganic and #medicinalchemistry research by 24 Jan 2025 to take part https://t.co/uAGSDaXXfx

[The Pratt Group @PrattGroup]

A great effort. What amazing things polysulfides can do - particularly with a bit of light. Congrats to the team @Chiba_Group @PrattGroup! More to come from this awesome collaboration.

[Chiba_Group @Chiba_Group]

Check out our new paper @Chem_CP on dearomative dimerization and skeletal rearrangement of quinolines under polysulfide anions photocatalysis, led by the great collaboration between Eugene, Amirah and Ali from @PrattGroup @Chiba_Group!

[ECOFR XV - 2024 @ECOFR_XV_2024]

Derek Pratt (@PrattGroup) discusses how natural antioxidants can inspire radical generation for chemical synthesis as part of this morning’s Keith Ingold Tribute Session #ECOFRxv

[ECOFR XV - 2024 @ECOFR_XV_2024]

The final programme for ECOFR XV is now live on our website! 👩‍🔬👨‍🏫

Complete with a full list of speakers, poster sessions, and reception times, the programme can be accessed through the link below!

https://t.co/pWJzSFpi1P

[James Olzmann @OlzmannLab]

Mark your calendars! The 1st FASEB #Ferroptosis conference, July 27-31 2025! We just posted our preliminary agenda! Spectacular line up and lots of space for short talks / late breaking speakers. Help us get the word out & come join us in 2025! @FASEBorg
https://t.co/VlV9L3jZHt

[The Pratt Group @PrattGroup]

A perfect day for a Pratt Lab BBQ! 🍔 Saying goodbye to Mike and celebrating his new beginnings over delicious food.

[HelvChimActa @HelvChimActa]

Derek Pratt @PrattGroup @uOttawaResearch opens #bsrc24 1st Symposium on Radical Vhemistry with his talk ‚No HAT Required!‘ @DCBPunibern

[The Pratt Group @PrattGroup]

Excited to share our latest review! Dive into the fascinating world of lipid hydroperoxides @dds_chem. Check it out for a comprehensive overview and new insights!
https://t.co/oSaD2gDP4Y

[SNE ChemBio @SNE_ChemBio]

“The Chemical Basis of Ferroptosis, Development of Tools to Study it and Design of Compounds to Inhibit it” by Prof. Derek Pratt (@PrattGroup, @uOttawa)
⏱️🇨🇭10:45 › 11:45
📢https://t.co/mJ7y0eXBuC

🧵2/3

[The Pratt Group @PrattGroup]

Amazingly, Carsten Berndt and Marcus Conrad @Conrad_Lab defied the odds and managed to herd cats! A must-have reference document for anyone interested in @Ferroptosis1. Thank you to everyone that participated to make this happen.

[James Olzmann @OlzmannLab]

Everything you've ever wanted to know about #Ferroptosis in Health and Disease! Massive review from many in the field. Happy to have contributed and huge thank you for the leadership from Carsten Berndt / Marcus Conrad @Conrad_Lab. 🙂
https://t.co/G0pE5O6378

[The Pratt Group @PrattGroup]

Awesome to see this story together. Great job Eugene, Ali and Amirah!

[Chiba_Group @Chiba_Group]

Check out our new preprint @ChemRxiv on dearomative dimerization and skeletal rearrangement of quinolines to indoles by polysulfide anions photocatalysis, that came out of a collaboration with @PrattGroup. Congrats to Eugene, Ali and Amirah! https://t.co/6rZGWFPkwZ

[The Renaud Group @renaudphi]

The first Bern Symposium on Radical Chemistry will be held on June 27-28, 2024 at the University of Bern.
We will have an exciting scientific program!
https://t.co/kg6G2T7BC3

[The Pratt Group @PrattGroup]

Go eHAT team! Congrats Luke and @ChengChem! It has been fun for us to be working to promote C-H oxidation rather than our usual gig of trying to slow it down. More fun to come with @StephensonLabUM and @maldonadogroup.

[Corey Stephenson @crjsteph]

Congratulations to the eHAT team on the newest publication out today in @J_A_C_S, led once again by the terrific collaboration between @ChengChem and Luke from the @PrattGroup @maldonadogroup @StephensonLabUM

https://t.co/HVVr91ABTR

[Angewandte Chemie @angew_chem]

Attenuating N-Oxyl Decomposition for Improved Hydrogen Atom Transfer Catalysts (Corey R. J. Stephenson and co-workers) @crjsteph @maldonadogroup @PrattGroup #openaccess https://t.co/wZM5PRWevp

[The Pratt Group @PrattGroup]

Another big round of applause goes out to Dr. Luke Farmer for enhancing the radical trapping capabilities of phenoxazine and phenothiazine through the assessment of non-tertiary alkyl substituents on the scaffold. Check out the paper @JOC_OL 👇
https://t.co/8m2aK0WW88

[The Pratt Group @PrattGroup]

Big congratulations to our lovely undergrad, Mike, for successfully completing his poster presentation! Amazing job and an excellent poster! 🌟