Philip Dunne

Molecular evolution in colorectal cancer. Professor in Belfast @QUBelfast & Senior Group Leader in Glasgow @CRUK_SI

[Philip Dunne @ProfPipDunne]

Massive congrats to @MallSid – just published in @NatureGenet

Our study defines a series of pathway-derived subtypes (PDS), which we use as the basis for identifying a previously overlooked phenotypic landscape in colorectal cancer…
https://t.co/JUE5IJqVtx

🧵👇

[Chris Tape @christophertape]

Link to bioRxiv: https://t.co/kmL88Oiqtm

[Philip Dunne @ProfPipDunne]

Another wonderful collaborative study from the Tape lab, that exemplifies the value of our CRUK CRC-STARS network 👇

[Chris Tape @christophertape]

Why do COX-inhibitors like aspirin and celecoxib help prevent and treat colorectal cancer (CRC)? Our new preprint suggests part of the answer is that they work as ‘anti-plasticity’ drugs. (1/7)

[Philip Dunne @ProfPipDunne]

The brilliant @RAmirkhah presenting her work at @EACRnews in Budapest.

Supported by @CRUKresearch @AlCRIproject

[Philip Dunne @ProfPipDunne]

The brilliant @RAmirkhah presenting her work at @EACRnews in Budapest.

Supported by @CRUKresearch @AlCRIproject

[Philip Dunne @ProfPipDunne]

What’s a bioinformaticians favourite TV station?

The tSNE channel.. 🥁

[Cancer Grand Challenges @CancerGrand]

What if a cancer-causing mutation were less like a ticking time bomb and more like an actor waiting for the right opportunity? Team SPECIFICANCER’s brand new paper gives us an insight.

The new paper from SPECIFICANCER, published in @Nature, reveals that it’s not just the mutation that matters — it’s where in the liver that mutation appears. Understanding which cells can turn cancerous — and why — helps us better predict risk and develop smarter, more targeted treatments.

Congratulations to the #CancerGrandChallenges SPECIFICANCER team (co-funded by @TheMarkFdn). This work was led by Owen Sansom and Future Leader Alex Raven.

👉 Read more from Alex: https://t.co/L4dpfswgRn

#CancerResearch

[Alex Raven @AlexRavenBio]

Very proud of all our hardwork! Exciting new paper exploring the origin of liver cancer https://t.co/bmmXgNlzFI
@owen_sansom

[Matthias Hardtke-Wolenski @HardtkeWolenski]

🔬 New review in Gut: Cutting-edge endoscopy, spatial imaging & AI enable real-time assessment of the intestinal barrier in IBD. Key to linking gut–brain–liver axes, predicting outcomes & finding new targets 🌱 @Gut_BMJ https://t.co/7dkO9grgTc

[Scott Kopetz @skopetz]

Exciting science and clinical efficacy in this @MDAndersonNews team science study led by @VanMorrisMD In Cancer Cell.
Triple therapy with IO led to durable responses in BRAF V600E MSS colorectal cancer, showing promise. Randomized study ongoing. #crcsm
https://t.co/yg5gyQRqNK

[Philip Dunne @ProfPipDunne]

@lauradelongwood Fantastic to meet you for the first time too, really enjoyed the company and the talk.

[Philip Dunne @ProfPipDunne]

What a week in Glasgow at the Beatson conference @CRUK_SI

Highlights for me were talks from Karuna @KarunaGaneshLab , Ken @KenLauLab and Laura Wood 🤩

And our very own Raheleh @RAmirkhah

[Ken Lau Lab @KenLauLab]

Thank you to @CRUK_SI and @DrPipDunne for a wonderful experience in Scotland for #BICC2025. Congratz to @K_Harsim for receiving the outstanding poster award!

[Philip Dunne @ProfPipDunne]

Great opportunity to catch up with so many people, to collaborate and discuss science with the speakers 🧬

Enjoyed playing a small part within the committee and looking forward to next year already.

[Philip Dunne @ProfPipDunne]

@Aiims1742 @skopetz @MDAndersonNews Very interesting. Happy to help with some deeper phenotyping analyses on the bulk if needed!

[The Johnston Cancer Research Centre @QubCancer]

We caught up with researchers from PGJCCR's @DrPipDunne Lab about their trip to April's @AACR Conference in Chicago. @NatalieFisher03 & @MallSid explained how it connected them with collaborators and set out to shape the direction of future research:
https://t.co/xpNzJBbgRl

[Anirban Maitra @Aiims1742]

HUGE congratulations to @skopetz @MDAndersonNews who will lead a multi-institutional consortium (CRC-ASCEND) on implementing adaptive clinical trials in #ColorectalCancer. Kudos to the whole team, including oncologists, program managers and patient advocates.
@fireflyann

[Cancer Screening & Prevention Research Group @CSPRG_Imperial]

Thanks @QUBelfast @HelenColemanQUB for inviting @DrAmandaJCross to give the Charlotte Jackson Gift Lecture today. A great opportunity to share our @CR_UK funded work on the early detection of #BowelCancer & how our findings are influencing policy and patient care #CancerResearch

[Philip Dunne @ProfPipDunne]

@qikipedia What a perfect sequence!

[Philip Dunne @ProfPipDunne]

@BEAUTIFULMUMSIE Thanks Lesley, just love Ayr and the surrounds, dreading when the kids get too old and bored of taking the ferry over for a few days.

[Philip Dunne @ProfPipDunne]

After 4 days of blistering sunshine on the Ayrshire coast with the family, heading back on the ferry to the homeland this evening.

Looking out at the 12 mile gap that is the closest points separating Scotland & Ireland. Absolutely love these two places
☀️☘️🏴󠁧󠁢󠁳󠁣󠁴󠁿☀️