Excited to share this work from former @PrunedaLab superstar @camgroberts! Cam tackled the challenge of identifying #ubiquitin regulators secreted by pathogenic bacteria, and found an entirely new type of E3 ligase that regulates P. aeruginosa virulence!
https://t.co/KgL0yYUek3
Fantastic to have @jnpruneda@PrunedaLab from @OHSUSOM visiting giving a seminar on his team’s exciting work on how pathogenic bacteria use nifty effector proteins to hijack the ubiquitin system and avoid the host response. Real pleasure to have you at @DTUbioengineer, Jonathan.
Our Annual Run4Raiden 5K is back! ⚡️🦓
This year's fundraising goal is to raise $60K to continue our UBA5 drug repurposing program. 🧬🔬
Sign Up or Donate Today: https://t.co/pYSY6SzkNv
@OHSUNews@jnpruneda@RuthJeanNapier
Excited to share the final product of this work, now available at @MolecularCell. Extremely proud of @tylergfranklin for this and many other achievements during his thesis work!
https://t.co/rpp6LOfeK3
Yesterday the @PrunedaLab produced its first PhD scientist! Congratulations @tylergfranklin on five years of incredible growth and science, capped by a fantastic thesis defense. Added bonus: his paper was accepted on the same day! Keep an eye on this one, he’ll do great things.
New preprint identifying shared and distinct mechanisms of inactivation of the #ubiquitin E1 enzyme #UBA1 across different diseases #VEXAS#SMA#lungcancer https://t.co/nPqiBmF5C7
Thanks to David Beck @nyulangone, @kyliejwalters and all contributors for a great collaboration!
Excited to share our new review on bacterial effectors that follow or break the "rules" of #ubiquitin signaling. Always a pleasure to work with @camgroberts and @tylergfranklin!
https://t.co/bLgLZm1rw8
Bacteria can counter noncanonical lipid ubiquitination with a #ubiquitin esterase! Fantastic collaboration with @ThurstonLab and @CMBI_Szczesna, with @r_lacoursiere driving our side of the project using some amazing tools built by the Geurink lab.
Excited to share our preprint on how a cytosolic bacteria evades LPS ubiquitylation and antibacterial autophagy through an effector with esterase activity. Led by @CMBI_Szczesna in the lab @ImperialInfect@CBRB_Imperial with superb collaborator @jnpruneda https://t.co/jvXqxWBMFu
What can bacteria teach us about #ubiquitin? A lot!
In our latest preprint, @tylergfranklin set out to understand how secreted bacterial ligases catalyze ubiquitin modifications during infection. What he found will surprise you!
https://t.co/IlOCPeg1uH
Happy to share that this work is now online in its peer-reviewed form at @MolecularCell. Huge thanks to our peer reviewers for challenging us, and to my co-authors for rising to meet this challenge. Check out the final product! https://t.co/IiiPi1VERJ
Grad student 1st time presenter @tylergfranklin impressed us all @FASEBorg Ub with cool Ub chain engineering; shown here with his PhD advisor @jnpruneda
I’m very excited to share our latest work, in which we identify, characterize, and apply a Legionella deubiquitinase that targets host Lys6-linked #ubiquitin signals with extreme precision. https://t.co/Tpf1kLUgv6
Ever tried to give a 3-minute research presentation? It isn't easy! @PrunedaLab member @camgroberts gave a fantastic flash talk at #UKcellmicro2021 this week and even won a prize! Congratulations to Cam and thank you to the organizers for such a great meeting!
Ever tried to give a 3-minute research presentation? It isn't easy! @PrunedaLab member @camgroberts gave a fantastic flash talk at #UKcellmicro2021 this week and even won a prize! Congratulations to Cam and thank you to the organizers for such a great meeting!
Huge congratulations to @PrunedaLab member @justinevnguyen for skillfully defending her Master’s thesis on bacterial deubiquitinases today! Well done Justine!