RebsamenLab

Pathogen & nutrient sensing in (auto)immunity #SLC #TLR | Dpt. of Immunobiology (formerly Biochemistry) @Unil | Views = our own

[RebsamenLab @RebsamenLab]

🚨 Abstract submission deadline: July 15th 2025🚨
Do not miss the opportunity to present your research: 10 selected short talks and an exciting poster session!
Register and submit your abstract here: https://t.co/0nyPZ9UFb9

[Immunobiology2025@UNIL @Immunobiology22]

We are excited to announce the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors, October 1-2, 2025, Lausanne, Switzerland���🇭!
Attendance is limited to 150 participants.
Registration and info: https://t.co/dw43nR4vYN
@DIB_UNIL

[Journal of Experimental Medicine @JExpMed]

We're looking forward to taking part in this meeting this October! JEM's Deputy Editor Gaia Trincucci (@Gaia_JExpMed) will be there – be sure to connect with Gaia to discuss your research and learn about publication 🔬💻✍️📄
#InnateImmunity #Immunobiology

[RebsamenLab @RebsamenLab]

Join us in Lausanne October 1-2 for the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors with an exciting line up of invited speakers!
Registrations are open and attendance is limited to 150 participants: https://t.co/0nyPZ9U7lB

[Immunobiology2025@UNIL @Immunobiology22]

We are excited to announce the 2nd edition of the Symposium on the Immunobiology of Pattern Recognition Receptors, October 1-2, 2025, Lausanne, Switzerland���🇭!
Attendance is limited to 150 participants.
Registration and info: https://t.co/dw43nR4vYN
@DIB_UNIL

[RebsamenLab @RebsamenLab]

Check out the Insights piece from A Blumenthal & L Dominguez Cadena @Blumenthal_Lab on our discovery of CCDC134’s role in Gp96 stability and TLR biogenesis.
Many thanks to the authors for discussing our work broadly, integrating recent studies by Rohatgi and Locher/Kaelin labs.

[Journal of Experimental Medicine @JExpMed]

Insights: from Cadena & @Blumenthal_Lab @UQMedicine: @RebsamenLab (https://t.co/OjJu71FkSO) show that CCDC134 located in the ER is required for TLR biogenesis by controlling the N-glycosylation, folding, and stabilization of the ER chaperone Gp96. https://t.co/cMTB6ZskXZ

[Broz Lab @broz_lab]

Check out our latest pre print! @AlexandraBoegli and colleagues show that the enigmatic inflammasome receptor, NLRP6 is activated by sterile and pathogen induced endolysosomal damage. Hot off the press!

https://t.co/Do65lx72gc

[Ales Drobek @AlesDrobek]

Huge thanks go to the @rebsamenlab and all the co-authors, LGTF_UNIL and great working environment and colleagues at @DIB_UNIL!
https://t.co/dQxNBbfIcV
https://t.co/A5yUDndgC6

[RebsamenLab @RebsamenLab]

Check out also the back-to-back paper from Paolo Manzanillo and colleagues at @Amgen

[RebsamenLab @RebsamenLab]

A big thanks to all co-authors!
This work was performed @DIB_UNIL with the support of @snsf_ch and the collaboration of our colleagues at the LGTF @unil and @CHUVLausanne.

Follow us on the blue side for more info!

[RebsamenLab @RebsamenLab]

Excited to share our latest paper out today in @NatureComms!

Great work led by postdoc @AlesDrobek showing for the first time the critical role in vivo of the SLC15A4/TASL/IRF5 pathway that we discovered few years ago.

#innateimmunity #autoimmunity

https://t.co/DbrHuoU7Ap

[Journal of Experimental Medicine @JExpMed]

This study from Bernaleau et al. @RebsamenLab @unil reveals CCDC134 as a central regulator of the chaperone Gp96, thereby controlling TLR biogenesis and responses. https://t.co/LT1UdIkg1g

#InnateImmunity #inflammation

[Fabio Martinon @fabiomartinon]

🚀 Exciting opportunity! 🎓 The PhD program in Cancer and Immunology in Lausanne is accepting applications! If you're passionate about advancing research in cancer or immunology, we want to hear from you! 🌟 #PhD #CancerResearch #Immunology https://t.co/o4VYUw0oyS via @unil

[Journal of Experimental Medicine @JExpMed]

Bernaleau et al. @RebsamenLab @unil use a loss-of-function genetic screen to identify the ER-resident protein CCDC134 as an essential regulator of Toll-like receptor (TLR) responses. CCDC134 binds and stabilizes the TLR chaperone Gp96. https://t.co/or0xBWE9Mn

[RebsamenLab @RebsamenLab]

A big thanks to all co-authors! This work was performed @unil with the support of @snsf_ch and in collaboration with the lab of @MajerOlivia and our colleagues @broz_lab at @DIB_UNIL!

PS: follow us on the blue side for more info!

[RebsamenLab @RebsamenLab]

Very happy to share our latest work just published in @JExpMed!

Our amazing PhD student @BernaleauL shows that CCDC134 controls TLR biogenesis through the ER-chaperone Gp96.
https://t.co/7DUre1EXh3

[Giulio Superti-Furga @giuliosf]

The time has come to identify my successor at @CeMM_News . Surprisingly, I feel serene about this process. Everything is prepared and aligned: CeMM is stronger than ever, with a formidable faculty and fully committed, empowered staff.

[Miriam Lisci @miriamlisci]

Could you live without glutamine?

I am delighted to share our preprint @jourdainlab: we employed parallel nutrient and genetic screeening to tackle the mechanisms promoting survival in glutamine-limiting conditions. Check it out 👇 more details below!
https://t.co/Ypy4JTpIT6

[Giulio Superti-Furga @giuliosf]

We are thrilled to share the THIRD study of our series which sheds light on the genetic interactions between transporters and links them to the metabolic network: https://t.co/BoNZEJjtM1

[Giulio Superti-Furga @giuliosf]

Do you want to know with which proteins an SLC membrane transporter socializes? Our @RESOLUTE_IMI series of 4 manuscripts continues, and we are excited to share the so far most comprehensive interactome mapping of solute carriers https://t.co/8WCyD81fbp

[Department of Immunobiology at UNIL @DIB_UNIL]

DIB day 2024 - another year of great achievements and exciting science from our department!!!

@DIB_UNIL @FBM_UNIL @unil

[Dr. Melanie Blokesch @MBlokesch]

Exciting news🤩- we have an opening for a tenure-track Assistant Professor in Infection Biology & Immunology in our Institute @epflSV @EPFL_en
Please spread the word & encourage outstanding postdocs, who are ready to start their own labs, to apply. THX 🤓
https://t.co/sRdINoKBb2