Great joint work with Niels Fischer, driven by joint first authors Thomas Schöndorf (UMG) and Valentyn Petrychenko (MPI-NAT), with important input from Ilgin Kotan and Günter Kramer (Heidelberg University), and the whole team — many thanks to everyone involved!
How do mitochondrial ribosomes keep pace with membrane insertion?
We address this question in our paper “Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed,” now out in Nature Structural & Molecular Biology (Link).
Congratulations to Prof. @A_Chacinska and Dr. Klaudia Maruszczak whose work has been recognized as a TOP Cited Article in FEBS Open Bio!
We are proud to see @IMol_Institute work inspiring further discoveries and advancing scientific knowledge worldwide.
#ResearchExcellence
Valenti et al. created a proteome-wide yeast degron library for rapid in vivo protein depletion. This tool enables dynamic protein function studies with minimal cellular rewiring https://t.co/ku49e1Sota
📕 From The Year In Cell Biology: https://t.co/Alo26NjqPH
#CellBio2025
We are thrilled to welcome in @IMol_Institute experts in mitochondrial research at the BioMit Symposium: Prof. N. Pfanner, Prof. P. Rehling and Prof. M. van der Laan!
The day is packed with science discussions, including Guests' speeches and sessions featuring IMol researchers.
My paper is out in @ScienceMagazine!
We found a novel host defense strategy where #mitochondria, our domesticated microbes, compete with the intracellular pathogen #Toxoplasma for #folate.
https://t.co/cDwlHtS4kB
New in @ScienceMagazine with a related Perspective
Mitochondria protect against an intracellular pathogen by restricting access to folate | Science https://t.co/3XG6kPNF7A
Silencing mitochondrial gene expression in living cells | Science https://t.co/wRDoCKbFzT - Now available in new Science issue. Thanks again to all colleagues for a wonderful collaboration. Awesome work of LD Cruz-Zaragoza!
Ein starkes Signal für Wissenschaft und Innovation! Vielen Dank an den Freistaat Bayern, @Markus_Soeder und @MarkusBlume für die Unterstützung beim Ausbau der #Spitzenforschung und der Life-Sciences in Bayern.
Our story about FASTKD5 is now published at @NAR_Open. It was an amazing collaboration with @hauke_hillen and @Antonio41949078 labs.
https://t.co/Ixj5LzMWwX
FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites
Our study on how mitochondrial methylation shapes gene expression is now out. Using long-read RNAseq and cryo-EM, we uncover two methylation-dependent checkpoints in ribosome biogenesis. Read all about it at: https://t.co/PJHQNPTEKm
SMIM20 promotes complex IV biogenesis and Ca2+ signaling in mice heart: Cell Reports https://t.co/Xx6Tn8yxGm. Great collaboration with @niels_voigt, @CZphenogenomics, D. Katschinski, & H. Urlaub. Thanks to Angela Boshnakovska, Laura Kremer and our lab!
Silencing mitochondrial gene expression in living cells | Science https://t.co/wRDoCKbFzT. Wonderful that our paper is out now in Science. A big thanks to LD Cruz-Zaragoza and the team, @warscheidlab & @JakobsLab .