Rob Beagrie

@WellcomeTrust Sir Henry Dale Fellow based at @HumanGeneticsOx, interested in chromatin disruption in human disease. He/him. Mastodon: [email protected]

[Rob Beagrie @RobBeagrie]

🚨 Job alert

Hiring a postdoc (comp or wet lab) to work on chromatin & genetics 🧬

Come work with us @HumanGeneticsOx in the beautiful @UniofOxford

🗓️ Closing September 13th

Details at https://t.co/TRLXH3hKfS

Pls share and RT!

#PostdocJobs #GeneticsJobs #genomics #cohesin

[Rob Beagrie @RobBeagrie]

Very happy to have been able to help out with this one - some very cool work! #genomics

[Jim R. Hughes @jrmmhughes]

Great collaboration between the @FoldingGenome and Watkins labs, reporting the first Gain of Function de novo enhancer causing Mendelian disease (ST Depression Syndrome), defining a multidisciplinary path with ML to solving non-coding clinical genetics.

https://t.co/0ShPzik8Le

[Wilkie Lab @Wilkie_Lab]

Calling all rare disease researchers and clinicians who have a variant of uncertain significance... 🧬

The @MRCMouseNetwork & @NMGN_CongAnom (co-led by our PI @srftwigg) are currently looking for VUSs to model in mice! 🐭

(1/2)

[Claudia Ribeiro de Almeida @cribdealmeida]

And it’s #PhDone! Rachel Kimber, first PhD student in my lab @BabrahamInst, has brilliantly defended her thesis today. Thanks to @carovinuesa and @viropractor for examining Rachael’s thesis. Well done, Dr. Kimber 🥳 🎉🥂

[Emily Brookes @EBrookesNeuro]

Fantastic day talking science @BigDataIns. Thanks for the invitation to share our research @RobBeagrie - it was great to see some familiar faces (the lovely Yang Shi!), put some faces to names/emails, and meet some new!

[Noelia Díaz @NoeliaDiaz27]

If you are willing to learn low input techniques to explore the chromatin of your favourite organism, don't hesitate to apply to this hands-on course! We'll be teaching you Low-C, ATAC-seq, CUT&RUN, and its bioinformatic pipelines.

[Rob Beagrie @RobBeagrie]

Applications are now OPEN for an internship in my group at Oxford University. Open to UK undergraduates from under-represented and disadvantaged backgrounds – apply by Wednesday 21 February 2024 to join us this summer: https://t.co/LboVIE2D8U

[Jannat Ijaz @sciencejannat]

Very excited to share that our work reconstructing chromothripsis has now been published in @CellGenomics! We reconstructed chromosomes with up to 800 rearrangements on a single allele and queried epigenetic and transcriptomic consequences. Thread below!

https://t.co/LWzYFYPPPV

[ISCB RegSys @ISCB_RegSys]

Submissions for technology track presentations are also open - go to https://t.co/buYA714cZm and apply by May 10th to showcase your bioinformatics/molecular biology software or hardware to the community #Bioinformatics #ComputationalBiology #ISMB2024

[ISCB RegSys @ISCB_RegSys]

You can now submit your new, unpublished work for publication as a proceedings paper at ISMB 2024! Full details are available at https://t.co/4juJsUg224 - the deadline is January 25th #Bioinformatics #ComputationalBiology #ISMB2024

[Emily Brookes @EBrookesNeuro]

Applications are now open for a fully funded @SoCoBioDtp PhD project with myself (@sotonbiosci ) and Jerome Swinny (@portsmouthuni) … please get in touch to discuss the project! Deadline Jan 8th.

[Nicky Whiffin @nickywhiffin]

Is anyone here using the UKBiobank 200k genomes dataset? We are having some weird issues and are trying to troubleshoot if data vs code 😬 Anyone else seeing anything odd?

Either way, please share! 🧬

[Mira Kassouf @MiraKassouf]

How cis-regulatory elements interact to regulate gene expression-role of CTCF and cohesin- check out our pre-prints @MRC_WIMM @jrmmhughes @FoldingGenome @RobBeagrie @JefBoeke @MolecularCell @NAR_Open @CTCF_Papers @generegulation

https://t.co/iQaza5Zc8G

https://t.co/f9RHDRYwpN

[Rob Beagrie @RobBeagrie]

If you know what you want to do and are ready to jump straight into a project, you might be interested in a DPhil in Clinical Medicine https://t.co/nEDIpEMWON - happy to talk through the differences with any interested candidates 3/3

[Rob Beagrie @RobBeagrie]

Looking to do a PhD in 2024? Interested in gene regulation, chromatin and disease? Applications are now open so come join https://t.co/yYXhZr9dg1 at the @HumanGeneticsOx ! Further details below but if you're interested DM me to talk about possible projects. Deadline Dec 1st 1/3

[Rob Beagrie @RobBeagrie]

There are two different DPhil programs you can apply to: if you want first-year rotations and more of a focus on computational biology then you might be interested in our DPhil in Genomic Medicine and Statistics https://t.co/snZeHOUPog 2/3

[Anton Henssen @anton_gh]

Congrats @apombo1 @LabPombo !!

[Andrew Newman @epiNewman]

Multiplex GAM is out! Congrats @LabPombo @apombo1 !!

Coming to a brain near you!!

https://t.co/1730QP365M

[Nature Methods @naturemethods]

Multiplex-genome architecture mapping (multiplex-GAM) facilitates rapid, unbiased and ligation-free determination of chromatin interactions, as compared to Hi-C.

@apombo1 @RobBeagrie @anto_scial @LonnieRWelch @LabPombo @helmholtz_de

https://t.co/eyfVaNuzZA

[Scialdone Lab @anto_scial]

The paper about CIARA - our method to find rare cells in scRNAseq data - is now published in Development!
One of the major additions to the preprint is the analysis of scATAC-seq datasets, showing how CIARA can find rare cells in other types of single-cell omic datasets too.