RJ Fu

🤔🤔🤔

[Bioinforbricker @hwkobe]

Glad to share this CRISPR study in @hxu1101 lab, working together with @Leon9168 and @Rongj_Fu, we performed high-throughput viability screens and off-target screens using two Cas9 variants: HiFi and LZ3 and revealed guide-specific loss of efficiency and off-target reduction.

[Cancer Discovery @CD_AACR]

Just published! We proudly present "Hallmarks of Cancer: New Dimensions" by Douglas Hanahan, the third update to the seminal series. https://t.co/bSer4maIjF @Ludwig_Cancer

[RJ Fu @Rongj_Fu]

Trying to use our MOFF for gRNA design and alleles-specific editing😊

[Bioinforbricker @hwkobe]

It’s a pleasure to share our recent study about CRISPR off-targeting and allele-specific editing, which is now published on @NatureComms. I’m glad to work together with @Rongj_Fu to finish this project under the guidance of @hxu1101.

https://t.co/b2qXqhMiis

[RJ Fu @Rongj_Fu]

Trying to play with our MOFF to predict gRNAs with high specificity!😊😊😊

[bioRxiv @biorxivpreprint]

Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity https://t.co/qhqTA5M5EG #bioRxiv

[bioRxiv @biorxivpreprint]

Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity https://t.co/qhqTA5M5EG #bioRxiv