Ryan Hobson

Postdoctoral Scientist at Mass General/Harvard Medical School. Open to work in Boston, MA

[Hannah Ennerfelt @EnnerfeltHannah]

Had a lot of fun writing this news & views for @NatImmunol⁩ paper by @RyanMHobson⁩ and ⁦@WassimElyaman⁩ - congrats on publishing this new “blueprint” of brain border immunity! https://t.co/pMMFhP4bSE

[Waggoner Lab @LabWaggoner]

Clonally expanded tissue-resident CD8+ T cells within the leptomeninges of individuals with neurodegenerative diseases
https://t.co/m3RSsPCqXe @NatImmunol preview by @EnnerfeltHannah https://t.co/iUNHjt44aS
@WassimElyaman @Columbia @RyanMHobson

[John Lukens @LukensJohnR]

Clonal CD8+ T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases
https://t.co/VUQTqrWcnn

[Ryan Hobson @RyanMHobson]

Excited to share that our paper is now live in Nature Immunology.

We identified highly expanded CD8+ T cell clones in the human leptomeninges and uncovered key changes in this immunological niche during neurodegeneration.

I am grateful to an incredible group of coauthors and collaborators, including @WassimElyaman, for their support on this project. @ColumbiaMed

https://t.co/iZL6098Yli

[Cathrine Sant @cathrine_sant]

CHOIR is now online @NatureGenet! CHOIR is a new clustering method for single-cell data that evaluates whether clusters represent statistically distinct cell populations. CHOIR scales to millions of cells and works with single-/multi-omic data of any type!
https://t.co/EKg20yMygH

[Ryan Hobson @RyanMHobson]

@WassimElyaman @NeilShneider @bradshaw2280 @soyonhonglab @samhslevy @DallinDressman @olivia_rifai It was a great symposium. Congrats Wassim, as well as the rest of the organizing committee

[Itai Yanai @ItaiYanai]

Doing good science is 90% finding a science buddy to constantly talk to about the project.

[Lehtinen Lab @LehtinenLab]

Out in @CellCellPress now with added data and analysis! @Huixin_BJ and colleagues report that the choroid plexus has specialized epithelial-immune synergy that modulates epithelial barrier plasticity during brain inflammation. https://t.co/sh8gHyKgOn

[Nature Neuroscience @NatureNeuro]

In a mouse model of #Alzheimer’s disease, amyloidosis itself triggers age-related #oligodendrocyte and #myelin damage mediated by CD8+ T cells that promote the accumulation of interferon-activated myelin-damaging #microglia

https://t.co/StqjJbezAX

[Ryan Hobson @RyanMHobson]

Great to see hard work being rewarded. Congratulations @ClaireFCastro @rosenzweig_a Jason Roh and all coauthors!

[Ryan Hobson @RyanMHobson]

Looking forward to sharing what we have discovered over the course of my PhD. Thanks @WassimElyaman for your support over the years!

[Wassim Elyaman @WassimElyaman]

Join us this Thursday, March 7th for Ryan Hobson's groundbreaking thesis defense on T cells in the degenerating brain @RyanMHobson @ColumbiaPS @Columbia

[eric hoyeon song @ericsongg]

Excited to share our group's first manuscript describing new anatomical connections that allow the eyes to act as an "immunological window to the brain" 👁️🧠 (1/)

https://t.co/mpIEqvZSE5

[Ryan Hobson @RyanMHobson]

@FOCISimmunology Congratulations @WassimElyaman and @KhosraviLabMayo !

[Sony Biotechnology @SonyBiotechInc]

Reserve your spot for our upcoming webinar to hear how the Elyaman lab at Columbia University has delineated a first-in-human comprehensive view of the immunological landscape in the brain and its borders with the #MA900 Multi-Application Cell Sorter.

➣ https://t.co/KJOao5cYVn

[Ryan Hobson @RyanMHobson]

@WassimElyaman @Columbia @WassimElyaman it was a great inaugural symposium. Inspiring talks from leaders in neuroimmunology and a welcoming environment to discuss science at the poster session over lunch. What more could you ask for?

[Ryan Hobson @RyanMHobson]

@smeetonlab @TroyAndFish @mulia_jo @Nature_NPJ @CSCIColumbia @ColumbiaGenDev Congratulations Troy and team!

[Nature Neuroscience @NatureNeuro]

A genome-wide in vivo #CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model

New from @kerlab @KawakamiLab @arekken @claradelarosa96 et al.

https://t.co/6i9DEyZM32

[Waggoner Lab @LabWaggoner]

CXCR6 orchestrates brain CD8+ T cell residency and limits mouse Alzheimer’s disease pathology @hongbo_chi @NatImmunol
https://t.co/Tctsn1P2fR

[John Lukens @LukensJohnR]

Senolytic therapy in mild Alzheimer’s disease: a phase 1 feasibility trial @NatureMedicine https://t.co/4mVRCAG9d3

[Ryan Hobson @RyanMHobson]

@ConnorMonahan8 @FGarrettiPhD @DAgalliu Congratulations @ConnorMonahan8 and team!