Excited to share our new @NatImmunol paper mapping the immune microenvironment and TCR repertoire in the border of the human degenerating brain using scRNA/TCR-seq and spatial proteomics @RyanMHobson@bradshaw2280 https://t.co/dEq2MoRGZM
Check out our partner studies showing that Alzheimer’s-linked CD33 variants promote binding of CD33 to CLU and to the immune phosphatase CD45, converging on impaired microglial plaque clearance and new therapeutic opportunities.
https://t.co/NNwRydcp4i
https://t.co/Sb7U2VUApX
We're about 3 months out from the 2nd annual T Cells in the Brain symposium! An expanded program this year, spread out over 2 days with an impressive lineup of speakers from around the world, reflects the growth in this important area. Submit abstracts at https://t.co/W58jUEE6oh!
Save the Date! Join us for the T Cells in the Brain Symposium (https://t.co/a6r7cNEvEB) on Jan 9-10, 2025, at Columbia University in NYC. Stay tuned for more details! #TCellsInTheBrain#Alzheimers#Parkinsons#ALS#Epilpesy
Thrilled to announce CUIMC 's T Cells in the Brain symposium on 01/12/24! Delve into talks spotlighting TCR repertoire, game-changing technologies and computational tools, and T cell-based immunotherapies in neurodegenerative diseases! #TcellsInBrain#TCB2024🧠 #CUIMC
An amazing paper from an amazing scientist I'm proud to share a bench with!
Check out our lab's new pre-print: Clonal CD8 T cells in the leptomeninges are locally controlled and influence microglia in human neurodegeneration
Excited to share a portion of my PhD thesis work on Biorxiv. Special thanks to @WassimElyaman for his guidance and support!
Clonal CD8 T cells in the leptomeninges are locally controlled and influence microglia in human neurodegeneration https://t.co/RRIyoY2Jvs
If you’re in Boston for the FOCIS annual meeting today, please consider coming by Salon A-D at 1:25 for my talk “Establishing leptomeninges immune dynamics and regulatory control of T cell infiltration in the degenerating human brain” #FOCIS2023
I am thrilled to share our new findings associating the depletion of a unique microglial subpopulation with #Parkinsons disease and characterizing the transcriptional and chromatin signatures of microglia in PD! Check it out -
https://t.co/kmXThzEyu9
@ParkinsonDotOrg
Our new study showing that Polygenic Risk Associated with Alzheimer's Disease and Other Traits Influences Genes Involved in T Cell Signaling and Activation https://t.co/Fmr11voE0N