Sandra Munro

[Illumina @illumina]

The next big thing in sequencing is coming. And it’s small. Learn more at our virtual event on October 9 at 9 a.m. PT: https://t.co/F9FYYpmS0P

[Ed Esplin, MD, PhD @EdEsplin]

@NCCN now includes #universal #germline #genetictesting for all #patients w/ #endometrialcancer/#uterinecancer

c/w https://t.co/WlkblDZwRN…
@gynoncjnls @ElsevierConnect @Invitae @Labcorp

i.e. recommends #germlinetesting for all #patients w/ #CRC or #EC <50, consider #germlinetesting for all #patients w/ #CRC or #EC >=50

#access #reducedisparities #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention #universal #germlinetesting #breastcancer #ovariancancer #endometrialcancer #colorectalcancer #pancreaticcancer

[Twist Bioscience @TwistBioscience]

Back by popular demand! The #MetGala as things seen in science…

First up, Cynthia Erivo as dark field microscopy blood cells:

[The Lancet Oncology @TheLancetOncol]

NEW

Results from the dose expansion groups of an open-label, phase 1b study of gedatolisib in combination with palbociclib and endocrine therapy in women with hormone receptor-positive, HER2-negative advanced breast cancer.
#bcsm

https://t.co/n007qKWQzk

[Paolo Tarantino @PTarantinoMD]

Phase 1b trial of gedatolisib (IV dual PI3K–mTOR inh) + palbo + ET for HR+ MBC out on @TheLancetOncol (n=103). ORR ranging between 25-85% depending on prior treatments. Non-negligible toxicities, with 89% stomatitis, 77% nausea, 76% neutropenia, 52% rash. https://t.co/28iSfOeyrB

[Sandra Munro @SBMunro]

@Aiims1742 It was a brand of antacid. In the novel Rebecca by Daphne du Maurier, Maxim says, "The only difference is that I don’t take Taxol, I prefer Eno’s, and you must never let me run out of my particular brand of toothpaste".

[Nature Reviews Drug Discovery @NatRevDrugDisc]

Resmetirom has just become the first drug for the liver disease NASH (also known as MASH) to gain FDA approval. Read about this advance and the pipeline of drugs such as FGF21 analogues, PPAR modulators, GLP1 agonists and oligonucleotide drugs here https://t.co/4GUS1nQOei (free)

[Sandra Munro @SBMunro]

Finding Endometrial Cancer Subtypes With Universal Testing With NGS https://t.co/8l1Cjj8cKs

[soria @jsoriamd]

Designing Best-in-Class Small Molecules needs to integrate advances in Chemistry, Cancer Biology, &amp; Data Science. Responses rates and prevalence across actionable targets is nicely summarized in this paper.
https://t.co/FbcHIYNW8V

[Hairy Cell Leukemia Foundation @HCLFoundation]

❣️ Just released, a look into Vemurafenib and Obinutuzumab as frontline treatment for Hairy Cell Leukemia.

A study years in the making, read here: https://t.co/z8ajlZ3JGt.

#ThisIsBloodCancer

[Sandra Munro @SBMunro]

So happy to see this published!
Increasing Clinical Trial Participation of Black Women Diagnosed with Breast Cancer https://t.co/siHMoJEea5

[Clinical Cancer Research @CCR_AACR]

Study on phase I trial efficacy and safety of #dostarlimab in patients with advanced or recurrent #EndometrialCancer and analysis of tumor #biomarkers as prognostic indicators by Oaknin et al. https://t.co/bIYQrWUY5L @CaraMath @ValentinaBoni7 @BanerjeeSusana @AACR

[Sandra Munro @SBMunro]

@JAMA_current Clinical Utility of Universal Germline Genetic Testing for Patients With Breast Cancer, JAMA Network Open, 2022
Altmetric Score of 330 - mentioned in 39 news articles! https://t.co/5R6MWRMY09

[Sandra Munro @SBMunro]

Safety, Efficacy, and Biomarker Analyses of Dostarlimab in Patients with Endometrial Cancer: Interim Results of the Phase I GARNET Study | Clinical Cancer Research | American Association for Cancer Research https://t.co/ybXAIr5Jvm

[Sandra Munro @SBMunro]

DNA sequencing improves cancer treatment but remains underused. Why? https://t.co/0EZaX1ZPAg

[Sandra Munro @SBMunro]

Check out the writing acknowledgement at the end! 😉

A Plain Language Summary of Results from the GARNET Study of Dostarlimab in Patients with Endometrial Cancer | Future Oncology https://t.co/1wBHcKZENL

[Providence Swedish Cancer Institute Research @ProvSwedCancRes]

Dr. Joshua Press co-authors a plain-language summary of ground-breaking research of immunotherapy research for endometrial cancer performed in part @ProvSwedCancRes #garnet 💍 #dostarlimab #immunotherapy https://t.co/VaxVbyS0nH

[Sandra Munro @SBMunro]

Is a Revolution in Cancer Treatment Within Reach? https://t.co/VpSZzdIvgx

[Megan Davies @EpiMegan_D]

Ever wondered how long it takes to reformat papers for journal submissions?

We did, and decided to write about it! We calculated time and money lost, interviewed journal editors and researchers, and developed some new guideline propositions.

Read here: https://t.co/QipLxjQIXp

[Sandra Munro @SBMunro]

@Dr_RShatsky Paperpile