SickKids Cardiac Precision Medicine Program

SickKids Cardiac Precision Medicine. Seeking to unravel the unique genome of every child with heart disease in an effort to deliver precision and timely care.

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

Drs @seema_mital, Joseph Rossano and Charles Canter shares insights on the SCOUT-HCM trial of mavacamten in adolescents at the @CCFheartkids (Children's Cardiomyopathy Foundation) webinar—advancing targeted therapies for pediatric HCM.

Watch here: https://t.co/bk3cmP6Fc0

[Heart Centre Biobank @hcbiobank]

Check out the latest Heart Centre Biobank Participant Newsletter to see how samples & data are driving research forward 💙

A big thank you to our participants—your contributions are advancing discoveries and improving heart disease outcomes.

https://t.co/vrG9QTqST7

[Ted Rogers Centre for Heart Research @trogersresearch]

An exciting new study in @NatureComms from a group researchers at @TBEP_UofT, @SKCardPrecision and @PMunkCardiacCtr & beyond is exploring a new approach to building more realistic human heart cell models using an algorithm-driven nutrient cocktail🧑‍🔬

https://t.co/4Dp9ekQH5R

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

Presented as a late‑breaking trial at #ACC25, this study was funded by @bmsnews and built on earlier SickKids Cardiac Precision Medicine stem cell research funded by CIHR & the @trogersresearch —a true bench‑to‑bedside win 🫀💙

@SickKidsNews story: https://t.co/YvCCSEqx4r

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

🌟 A major advance for children with heart disease 🌟
A landmark @NEJM study shows that mavacamten, a targeted cardiac therapy, can safely reduce dangerous heart obstruction in adolescents with obstructive HCM.

https://t.co/OjKT705izX

SickKids Leads: @JediJeewa @seema_mital

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

The global Phase 3 SCOUT‑HCM trial showed improved heart structure, function, and symptoms—without compromising heart pumping function. This is the first randomized Phase 3 trial of a disease‑targeted therapy in adolescents with obstructive HCM.

[Ted Rogers Centre for Heart Research @trogersresearch]

📣Trainees now attend FREE!

C4U 2026 is a one-day cardiovascular & critical care conference, now free for all trainees. Includes expanded Simulation Lab featuring ECMO, Impella, LVAD & more. Use code C4URESIDENT.

April 10 | Toronto
🔗 Register: https://t.co/C8AIbGKc41

[Ted Rogers Centre for Heart Research @trogersresearch]

A new study in @JACCJournals reveals a clear molecular signature behind diastolic dysfunction in children with cardiomyopathy, pointing to abnormal lipid signaling as a key driver.
Researchers also identified a potential blood-based lipid “fingerprint”
🔗 https://t.co/cQIpoJ4oPA

[Ted Rogers Centre for Heart Research @trogersresearch]

Calling all cardiologists and trainees! Early bird registration for the C4U Clinical Cardiology and Critical Care Update Conference has been extended until Feb 15! Learn more and register today to sign up before rates go up 💸 https://t.co/C8AIbGKc41

[Ted Rogers Centre for Heart Research @trogersresearch]

🎉The 2026/27 TRCHR Education Fund is now accepting applications for projects supporting collaborative, heart failure–focused research across TRCHR partner institutions!

PhD Awards: $25,000
Post-Doc Awards: $40,000

Apply by March 30, 2026
https://t.co/7JQ2KyVDFj

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

New Publication in @GenomeMedicine:
“DNA methylation analysis of NOTCH1 variants reveals the first episignature for nonsyndromic CHD.”

✅Largest CHD cohort analyzed (3,907 cases)
✅ NOTCH1 = most frequent monogenic cause
✅ First DNAm episignature

https://t.co/1IQS72LvPa

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

Cardiac Precision Medicine in the 21st Century| October 29-31, 2025 | Toronto

We were thrilled to bring together leading experts, researchers, and clinicians—a multidisciplinary international community united by the goal: improving heart outcomes through precision medicine.

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

Thank you for joining us at the Intl. Cardiovascular Genomic Medicine & SickKids Cardiac Precision Medicine Conference! 🌍

We welcomed experts from 14 countries to explore #CardiacPrecisionMedicine in the age of Omics, AI & digital health.

📸 Highlights coming soon!

[Valli Subasri @vallisubasri]

So exciting to see this presented by Dr. Frederick Roth at today’s Cardiac Precision Medicine Conference hosted by @SKCardPrecision, and now officially out!

[Barbara Cifra, MD 🫀🇮🇹🇨🇦 @BarbaraCifra]

Loved speaking @SKCardPrecision ! 🎙️
Shared how personalized exercise can help optimize health for patients with #HCM — true #PrecisionMedicine in action.
#ExerciseIsMedicine #HeartHealth

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

Thrilled to have @EdgewiseTx join us in Toronto for the Cardiac Precision Medicine in the 21st Century Conference! Let’s advance the future of heart care together.
#CardiacPrecisionMed

[Edgewise Therapeutics @EdgewiseTx]

We’ll be at the 10th International Cardiovascular Genomic Medicine & SickKids Cardiac Precision Medicine Conference in Toronto! We're proud to be a sponsor, bringing experts together to discuss cardiovascular genomics & precision medicine. @GenomFoundation @SKCardPrecision

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

⏳ Last chance to register! ⏳
Cardiac Precision Medicine in the 21st Century Conference
📅 Oct 29–31 | 📍 Toronto + Virtual

🔬 Genomics, Multi-Omics, AI, Precision Therapies & more

🎓 In person discounts for @trogersresearch: SickKids, UHN, U of T
🔗 https://t.co/BXe3rq05ug

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

⏳ Less than 2 weeks to go!
Cardiac Precision Medicine in the 21st Century Conference 🫀✨

Huge thank you to our industry sponsors:
🔶 Gold: @illumina
🔷 Silver: @PacBio, @sanofi, @Standard_BioT
🔸 Bronze: @EdgewiseTx, @bmsnews

https://t.co/qCbmHy9dnp

[SickKids Cardiac Precision Medicine Program @SKCardPrecision]

Join us at the Cardiac Precision Medicine in the 21st Century Conference for a special session sponsored by @illumina

🗓 Thurs. Oct 30 | 🕢 7:30 AM | 📍SickKids

🎙 Dr. David Lanfear
🧬 Making Precision More Practical: Design and Results of the CardioSeq Clinical Trial

[Heart Centre Biobank @hcbiobank]

Wonderful weekend at the @SKHeartCentre Family Conference!

Grateful to connect with families & share the work of the @hcbiobank , @SKCardPrecision and the @trogersresearch

Thanks to LFHC for the invite & to all who stopped by to say hi and learn more! 💙

#PrecisionMedicine