Stephan Ledain

building @adapt_ai_ @eternal_remedy
art | psychology | AI 👨🏿‍💻⬇️

[Stephan Ledain @sledain]

Old Twitter was funnier.

https://t.co/OiGrVzoBgd

[Stephan Ledain @sledain]

@elonmusk lol no. no it won't.

[Stephan Ledain @sledain]

@naval @JTLonsdale This is an obviously lazy take, but more so reads as if you've never tried to model a large amount of behavioural data. There are consistent, replicable patterns even where our capacity to theorize lags.

[Stephan Ledain @sledain]

@karpathy This is brilliant, @karpathy. Grateful for your generosity in sharing insights. I wonder if a useful guardrail for an LLM council is to let go of deep analysis and just “trust its gut” (limit the time in analytical reasoning) to avoid overthinking.

[Stephan Ledain @sledain]

LLMs are not the bridge to enterprise AI adoption. They're helpful at times, not transformational. We need genuinely emergent applications that are rooted in new ways of working to realize the AI valuation narrative.

[Stephan Ledain @sledain]

@Heyits_Gaurav @bindureddy Or further exacerbates the anxiety... because they'll be left with the weight of a self-determined life without the support of a work-related institution. There's evidence to suggest that for some, this could cause more harm.

[Stephan Ledain @sledain]

@Heyits_Gaurav @bindureddy The data supports this take more than any others

[Stephan Ledain @sledain]

Yes and that is by design.
No one wants to be anything like LA.
This is the gift you've given to us.

[Los Angeles Dodgers @Dodgers]

THEY STILL NOT LIKE US. #WORLDSERIES

[Stephan Ledain @sledain]

This is one of the most beautiful and perfect game 7s ever.

[Stephan Ledain @sledain]

@foundmyfitness @PeterAttiaMD It's really cool how much you're drawing attention to the large body of creatine literature. I'd love to see more human trials explore adverse effects. Anecdotally, I've felt pain in the kidney area from taking more than 5g.

[Stephan Ledain @sledain]

Here's what I think the future looks like written by Harry Shaan

AI x Creativity: Stephan Ledain and the Probability of Wonder
https://t.co/W1DRgaJtdn

[Stephan Ledain @sledain]

@emollick This also highlights the safety risks of capabilities outpacing alignment and maybe counterintuitively, a pause to focus on alignment may be more lucrative for the big research houses.

[DCinvestor @DCinvestor]

on @OpenAI GPT-5:

irrespective of whether you consider GPT-5 better or worse than prior models (and beyond some of the technical failings which i’m sure will get fixed at some point)

a lot of the pushback i’m seeing is along the lines of the fact that it is *different* than what people are accustomed to

in other words, people have spent the past 1+ years deeply integrating LLMs into their lives to such a degree that they learned how to work with them- including an understanding of their strengths and weaknesses, and how you need to handle them to get the most out of them

when the models change significantly in how they engage with you in a new release, it disrupts that experience. it’s like getting a new coworker. it doesn’t *feel* right anymore

the future of these models has to be some kind of “personas” which you can control, so that engagement is highly tailored to your preferences, and the logic gets upgraded on the back end with subsequent models while the engagement style with you remains the same

i don’t know when we get there, but that is my takeaway from the GPT-5 situation so far

[Stephan Ledain @sledain]

People are literally more anxious and chaotic in this era

[Stephan Ledain @sledain]

@RealDoctorMike @EricTopol @PeterAttiaMD Can we talk about the trust and resistance obstacles standing in the way of effective AI adoption in medicine? Especially in the era of scientific doubt.

[Ben Stiller @BenStiller]

In what universe does a 60 million dollar opening for an original studio movie warrant this headline?

[Stephan Ledain @sledain]

@aliciakatz We stand on guard for thee.

[Stephan Ledain @sledain]

@NaomiSharon What are the Tariffs on these, the best of Toronto's exports?

[Stephan Ledain @sledain]

@cathsimard_ Sorry you're going through this. It probably should be a multi-pronged approach. There's intense evidence for CBT, SSRIs (for a limited duration), breathwork and meditation, and most importantly, as you're doing here, community.

[Stephan Ledain @sledain]

Lmao Ramit responding to rebuttal in this thread is generational

[Ramit Sethi @ramit]

Good evening, MAGA voters. Thanks to your vote, you'll now pay thousands of dollars more per year.

Let's begin by taking a tour of your grimy homes.

In your kitchen:
- Coffeemaker: Likely made in China, Thailand, or Malaysia. You'll now pay 24%–36% more
- Sponges: Enjoy the 34%–46% tariffs

In your bathroom:
- Towels: Many are made in India, Pakistan, or Turkey. Enjoy 26%–29% tariffs
- Toothpaste & body wash packaging often comes from EU, China, or Vietnam. 20%–34% more

In your garage:
- Power tools Often made in China, Taiwan, or Mexico with 32%–34%+ tariffs (thankfully I don't have to worry about this one)

And I'm not even mentioning the expensive stuff, like your cars, appliances, HVAC, furniture, and TVs

You'll pay thousands of dollars more for household items...all so that wealthy guys like me can get a tax cut that I don't need. This is what Republicans voted for