The STARRT-AKI Trial

A Multi-National RCT of Standard Versus Early Accelerated Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury (NCT02568722)

[The STARRT-AKI Trial @STARRTAKI]

New @STARRTAKI publication! What is the impact of RRT initiation strategies among patients with CKD? @drseanbagshaw @DrRonWald @BellomoRinaldo @kidneybloke @orlasmith51 See new secondary analysis at: https://t.co/UXEQqx32An @yourICM

[Sean Bagshaw @drseanbagshaw]

New publication from @STARRTAKI - reanalysis of the main trial outcomes using a Bayesian approach @f_g_zampieri @DrRonWald @LamontagneFran5 @Bram_Rochwerg @CCCTG_ @UAlberta_ICU
https://t.co/NqQQWj0WsH @Crit_Care

[Sean Bagshaw @drseanbagshaw]

New @STARRTAKI publication! Is there heterogeneity in treatment effect of RRT initiation strategies on outcomes by baseline risk of receiving RRT? @DrRonWald @AnnalsATS @CCCTG_ @UAlberta_ICU
https://t.co/dI57zDoUhT

[Sean Bagshaw @drseanbagshaw]

Embedding equipoise into eligibility criteria of RCTs can be challenging. @STARRTAKI has now described and shared insights into this process https://t.co/8MgUrHqkmY @DrRonWald @CCCTG_ @anzicsctg

[The STARRT-AKI Trial @STARRTAKI]

10/10 - No. of days from the first patient randomized to trial publication in @NEJM: 1738

https://t.co/roNVRDZpjx

@drseanbagshaw @DrRonWald @UAlberta_ICU @SMHcriticalcare @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

9/10 - No. of days from the first to the last patient randomized into the trial: 1437 (3 years, 11 months, 6 days)

@drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

8/10 - No. of languages used for trial-related documents and communication: 5

@drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

7/10 - No. of research grants received to support the trial: 10

@DrRonWald @drseanbagshaw @CCCTG_ @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

6/10 - No. of "site initiation visits" performed: 116

@drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

5/10 - No. of completed data queries during database cleaning: 16,825

@DrRonWald @drseanbagshaw @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

4/10 - No. of trial-related emails (estimated): >60,000

@drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

3/10 - N. of trial-related teleconferences and webinars for @STARRTAKI: 414

@drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

2/10 - No. of database entries for all patients enrolled in @STARRTAKI: 886,149

@drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

@STARRTAKI Index fact for today:

1/10 - No. of investigators and research personnel (across 15 countries & 168 activated sites): 840

@drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

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[The STARRT-AKI Trial @STARRTAKI]

@STARRTAKI results very soon! Stay tuned. In the meantime over the few days we will share the "STARRT-AKI Index" - a summary of fun facts related to the trial @drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

[The STARRT-AKI Trial @STARRTAKI]

Thanks again to all our investigative teams for their commitment and global collaboration to successfully complete the @STARRTAKI trial - results of the main trial will be available soon @drseanbagshaw @DrRonWald @CCCTG_ @anzicsctg @ICCCTN @UKCCRGroup

[The STARRT-AKI Trial @STARRTAKI]

We are proud to announce @STARRTAKI has completed target recruitment of 3000 patients! Huge kudos to our investigators, research teams, and patients/families in 15 nations and 168 sites! @drseanbagshaw @DrRonWald @CCCTG_ @anzics @UKCCRGroup @ICCCTN 🇨🇦🇦🇺🇦🇹🇧🇷🇧🇪🇨🇳🇫🇮🇫🇷🇩🇪🇮🇪🇮🇹🇳🇿🇨🇭🇬🇧🇺🇸

[The STARRT-AKI Trial @STARRTAKI]

Happy weekend to all our investigators and coordinators, all our participating intensivists, nurses and patients and any interested followers! @STARRTAKI is 2958/3000 complete! Magic number is 42! Help us in this final push! @drseanbagshaw @DrRonWald @CCCTG_ @anzics @UKCCRGroup

[The STARRT-AKI Trial @STARRTAKI]

Congratulations to the Team from Juravinski Hospital (Hamilton 🇨🇦) for enrolling their 💯th patient into @STARRTAKI! Magnificent contribution & inspiring dedication! @drseanbagshaw @DrRonWald @CCCTG_ @Bram_Rochwerg @TKarachi_MD Happy 🇨🇦 Day to all our amazing Canadian sites!

[The STARRT-AKI Trial @STARRTAKI]

Kudos to University Hospital Ayr (Scotland🏴󠁧󠁢󠁳󠁣󠁴󠁿🇬🇧) for randomizing their 1st patient into @STARRTAKI! @drseanbagshaw @DrRonWald @CCCTG_ @dfmcauley @UKCCRGroup #aki #rrt #starrtaki