Saige Power

Postdoctoral neuroscientist with my *attention* on the prefrontal cortex. Art, photography, & thinking about thinking.(they/them)

[Saige Power @SaigePower]

Rescuing nicotinic responses in aging by harnessing muscarinic signaling pathways. I'm so excited to have this project out, thank you @Sridevi292 @LambeLab @physiologyuoft. Check it out here https://t.co/wgyl9dqnZe

[ELambe @LambeLab]

Need to recover lost #nicotinic currents? It is possible even in the older brain with #xanomeline & #NS9283. Paper now @npp_journal Kudos to stellar graduate students @saigepower @sridevi292 @physiologyuoft Here's the link: https://t.co/lv4Q9e3dve

[Saige Power @SaigePower]

Curious about endogenous serotonin and SSRIs in the mPFC? 🐁⚡️💊

Come by my poster today at @CAN_ACN

[ELambe @LambeLab]

@Luna3150 @physiologyuoft used optophysiology to show that #CCK interneurons inhibit ventral hippocampus neurons tagged with #retrobead labelling from the nucleus accumbens. Great working with @jckimlab again!

[Saige Power @SaigePower]

I’m at #SfN2023 presenting my latest work in the @LambeLab. Come visit…

🐁 C10 (ACh in Alzheimer’s)
⚡️ C41 (Serotonin in PFC)

Our Alzheimer’s work is now on bioRxiv (https://t.co/jkjUCJUXDy) and you can come ask me questions Tuesday (tomorrow) morning from 8-12pm at C41!

[bioRxiv @biorxivpreprint]

Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer's disease models https://t.co/GKstp9uX1O #bioRxiv

[Saige Power @SaigePower]

Great to be working with @d_sargin @LambeLab & @mark_ansorge + team!

[Nuno Dinis Alves @ndinisalves]

🗣️ Happy our manuscript is taking shape!
"Serotonergic input into the mPFC regulates cognitive flexibility"
@AshleaIsHere @mark_ansorge
Another great collaboration with @LambeLab!

Check it out on BioRxiv.
👇
https://t.co/NXFo1uPppx

[Saige Power @SaigePower]

Exciting NMDA receptor work from great current and former lab mates @Sridevi292 @binko_mary and collaborators @camielnik @ajr937

[ELambe @LambeLab]

What happens when Grin1 deficiency leaves neurons with too few NMDA receptors (NMDARs)?

Turns out there is a selective loss of extrasynaptic NMDARs compromising dendritic plateaus.

Adult genetic intervention can bring them back!

NMDARs #beingextra

https://t.co/tljhs4n9ag

[ELambe @LambeLab]

So happy to be back in person at #SFN22 with nicotinians @MarinaP63 Dan McGehee Bill Green @LambeLab @Sridevi292 @SaigePower #SFN2022

[Saige Power @SaigePower]

@laurmedlock Can’t wait!!

[Saige Power @SaigePower]

@sinclair_allie Yes, next time!

[Saige Power @SaigePower]

Excited to be here at #SfN2022 ! Come chat with me about cholinergic deficits in aging & nicotinic rescue by xanomeline on Monday afternoon at poster D31!

[Saige Power @SaigePower]

@iampritishpatil Yes it’ll be so good to see you again!

[ELambe @LambeLab]

1/ Patch clampers at #SFN22! Postdoc opening @LambeLab in Toronto 🇨🇦. Neuromodulation and plasticity of prefrontal cortex. Small lab, great colleagues, vibrant city. MONDAY afternoon, come by our #SFN2022 talk & posters (344.03, 360.05, 360.08) to say hi... links below

[Saige Power @SaigePower]

Happy Halloween from the lab rats! 🐁 🎃 🥼 @AMereCause

[Saige Power @SaigePower]

I may be "bi"ased but I'm looking forward to the work that'll come out of this on #bisexual health & well-being!

[Saige Power @SaigePower]

A bird for the bird app. Red tailed hawk spotted in @GreenWoodHF during a lovely long weekend with @AMereCause in nyc

[Saige Power @SaigePower]

@Przy_PhD We’ve been using @EasyElectrophys lately & really liking it!

[Saige Power @SaigePower]

@sdglasgow @Sridevi292 @LambeLab Thank you Stephen, I appreciate it!!

[Saige Power @SaigePower]

@laurmedlock @Sridevi292 Thank you!! 😊

[ELambe @LambeLab]

Xanomeline restores nicotinic receptors to cholinergic synapses in aged mice. First preprint and elegant work @saigepower @sridevi292 @physiologyuoft #acetylcholine #muscarinic #nicotinic #aging https://t.co/FbkosuBAuy

[Saige Power @SaigePower]

Looking forward to #CAN2022 this week! I’m presenting my poster on aging and prefrontal cholinergic signalling on Sunday from 1:30-3:30 (P3-B-39) @CAN_ACN. Come on by to see mine and @LambeLab‘s work!