Hemotional results. Dedicate to all patients with pancreatic cancer. Results like this one makes me a better clinical investigator and physician when I’ll go back in clinic next week.
An INCREDIBLE advance in pancreatic cancer. Compared to conventional treatment, Daraxonrasib, a new RAS inhibitor, was shown to increase survival in metastatic pancreatic cancer in this landmark NEJM trial:
> Median survival doubled
> 12-month survival tripled (18% to 53%)
> Less discontinuation (1.2% vs 11.2%)
Pancreatic cancer carries one of the worst prognosis - most cases carry a KRAS mutation which is targeted by this new class of treatment, bringing much needed hope to patients with this cancer, and potentially affecting other sites 🤞👏
https://t.co/bqHKoh1qS3
Cheers, chills, and a standing ovation when RASolute 302 showed unprecedented survival on daraxonrasib for patients with progressive pancreatic cancer
Seldom do you sense you’re witnessing a historic moment in cancer care but this feels like ras targeting has arrived
#ASCO26
Presented at #ASCO26:
Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results: https://t.co/xwLWBZYRzq
@ASCO
@JAMASurgery Different approach same surgical principle…wish leads me to the conclusion of lack of surgical principles, error of judgment or insufficient robotic training were the cause of higher recurrence.
Robotic-assisted groin hernia repair was associated with a higher long-term operative recurrence rate than laparoscopic or open repair among #Medicare beneficiaries, with overall recurrence rates remaining low across all methods.
https://t.co/qY9rxbfYJS
The mean age of physicians who leave clinical practice in the US is now 48.1 years, 9 years younger than observed in a similar cohort in 2008.
The biggest causes cited were stress and the hassles of practice.
11% of women decided not to even enter practice.
What are your thoughts about this?
https://t.co/eXmYbeOoOF
Men lose 38% less weight on GLP-1ra medications in this study of 64 randomized controlled trials https://t.co/kdWybcYx1p #obesity#bariatricsurgery#GLP1
Phoebe played six new songs again tonight in Macon, GA, as well as singing Georgia twice (because she messed up the first time and wanted to do it right for the Georgians)!
A man spends 50 years teaching at MIT.
He knows his time is running out.
So he records one last lecture — everything he knows, distilled into a single hour.
He died 5 months later.
This is that lecture.
The most important hour you'll watch this week. 👇
Bookmark it for later
Instead of watching an hour of Netflix, watch this 2 hour hour Stanford lecture will teach you more about how LLMs like ChatGPT and Claude are built than most people working at top AI companies learn in their entire careers.