a4b7 biosim (vedolizumab) is already out, Sandoz is developing a Skyrizi Il23 biosim (LOE 2033), so that's 2/3 of its combo strategy... where is the IP moat?
SPY120: Co-formulation combination of SPY001 (anti-α4β7) + SPY002 (anti-TL1A) in Phase 2 SKYLINE trial for UC.
SPY130: Co-formulation combination of SPY001 (anti-α4β7) + SPY003 (anti-IL-23) in Phase 2 SKYLINE trial for UC.
SPY230: Co-formulation combination of SPY002 (anti-TL1A) + SPY003 (anti-IL-23) in Phase 2 SKYLINE trial for UC and immune-mediated diseases.
This! Co-formulation is the way (don't believe us - see $ABBV CEO note, see $JNJ see $SYRE. CoFormBio is first AI/SI immunology company focused on solving the efficacy cliff with rapid development combination therapies of validated targets with novel co-formulation IP, powered by our AI/SI engine, CoFormForge. It is not an afterthought/pivot or pipeline rescue strategy for us. It is our strategy. If you are a believer - drop a dm.
@RecursiveChris@mkoeris@Tesla 🎯 again I don’t love the tech/auto analogue BUT their respective “halo” or moonshot tech products showcasing the bleeding edge of innovation, often trickles down to, and benefits consumer accessible products…
We’re building an AIxBio company. The hard part is the biology. The operating model we are striving towards is new - it is what this Replit post describes - a small team running development, BD, legal, finance, and ops through agents instead of building a full headcount for each. https://t.co/FnQD2VwR1p