Congrats @Frafrap1987 for this achievement and clear data: addition of a #platinum agent to standard #neoadjuvant#chemotherapy increases #pCR rates by 20% but no benefit for #BRCA patients (that have already high pCR rates with standard CT) #ASCO18
Happy knowing both top #oncology societies,which I am a member of @ASCO & @myESMO care about #Oncology#fellows .Remember: @Annals_Oncology paper on #burnout . If a fellow, read it,if senior recognize it.Take care of your fellows,they will take care of you https://t.co/gT5nG9hDhM
Meta-analysis of ovarian suppression during chemo to preserve fertility.
Amenorrhea at 2 years: 18% with GnRH agonist, vs 30% without
More pregnancies in GnRH group. No pregnancies after age 40.
No impact on DFS or OS.
Thus, GnRH protection is safe and preserves fertility.