Sayari Bhattacharya

SRF || Interested in Protein 🧫 ML 👩🏽‍💻 Music🎶sports🏟️ Food🌯 Movies 🍿

[Nicholas Fabiano, MD @NTFabiano]

Feeling stupid is a crucial part of science.

It means you're pushing into the unknown where real discoveries happen.

[Unfiltered @quotesdaily100]

10 SUBJECTS THAT WILL MAKE YOU SMARTER:

01. Psychology
02. Economics
03. Philosophy
04. History
05. Mathematics
06. Neuroscience
07. Linguistics
08. Political science
09. Behavioural science
10. Sociology

[Philosophy Of Physics @PhilosophyOfPhy]

Visualization of Stokes' Theorem.

[Curious Minds @CuriousMindsHub]

How To Remember Everything you Read

[aesthetic @purepeaceful]

Kyoto, Japan

[Valeriy M., PhD, MBA, CQF @predict_addict]

Glad I finished my PhD before the LLM era.

A PhD done with heavy LLM reliance risks becoming like learning to drive in a self-driving car — you arrive, but never really learn how to control the machine.

At that point, what exactly are you training: a researcher, or a prompt operator?

[Latest in Culture @latestinculture]

“Any woman is just as capable of being a hero as any man."

Hayao Miyazaki

[TUPACABRA @tupacabra]

It's probably nothing...

[Suman Chakrabarty @SumanPhysChem]

Our PathGennie work has been highlighted by DST @IndiaDST in a press release:
https://t.co/9O5m73olyE
Thanks to @ANRFIndia and @snbkol for the support.

[Math Cafe @Riazi_Cafe_en]

MIT's "Matrix Calculus for Machine Learning"

Lecture Notes: https://t.co/cu7uySAgMG
Video: https://t.co/npDfazVfez

[Jeffrey West @mathoncbro]

Fascinating (& terrifying) article published in Science, on AI-assisted writing of scientific manuscripts.

Authors find evidence of:
1) accelerated research output due to LLMs
2) especially true of non-native English speakers
3) a complete reversal in correlation between writing complexity and publishability (!)

https://t.co/qUjyCB1QCX

[Sayari Bhattacharya @Sayari_2000]

@MAITYDIBYENDU99 @ClashofClans Th14! Why?

[Sayari Bhattacharya @Sayari_2000]

@crazytoqether May be it's the moment he tried to tap into the Hive mind again but failed. Instead, hive mind took control over him and going to use him to kill others! So, he is saying everyone to run away from him... Also, I think he's probably going to die in the end.

[Sayari Bhattacharya @Sayari_2000]

Congrats @MAITYDIBYENDU99 🎉

[Suman Chakrabarty @SumanPhysChem]

Our team @snbkol introduces PathGennie (just published in @JCIM_JCTC), a fast and unbiased computational framework for uncovering rare molecular events such as drug unbinding and protein folding.

Instead of using any biased forces or elevated temperatures, PathGennie launches ultrashort unbiased MD trajectories and selectively propagates only those that show real progress toward the transition. This lets us generate complete rare-event pathways in just 10–100 ps, while preserving true molecular dynamics.

Full credit goes to my PhD student Dibyendu Maity @MAITYDIBYENDU99 for formulating and implementing the PathGennie code. Thanks to @ANRFIndia for funding.

✨ Key Highlights:
• Identified 7 distinct unbinding routes for benzene from T4 lysozyme
• Recovered all major exit pathways for imatinib from Abl kinase within a handful of attempts
• Captured folding/unfolding pathways of Trp-cage and Protein G that align with minimum free-energy paths
• Weighted Ensemble (WE) simulations converge 3–4× faster when initialised with PathGennie-generated pathways
• Path finding works even with suboptimal CVs

🔗 Try our code: https://t.co/pO8gfhZNda
📄 Read the paper: https://t.co/jThJvhBTjW

#CompChem #RareEvent #EnhancedSampling #MolecularDynamics #PathSampling #DrugDiscovery

[Sayari Bhattacharya @Sayari_2000]

Hypocrisy is a mental illness

[J.K. Rowling @jk_rowling]

If you believe free speech is for you but not your political opponents, you're illiberal.

If no contrary evidence could change your beliefs, you're a fundamentalist.

If you believe the state should punish those with contrary views, you're a totalitarian.

If you believe political opponents should be punished with violence or death, you're a terrorist.

[Sayari Bhattacharya @Sayari_2000]

@MAITYDIBYENDU99 @elonmusk 🤣🤣🤣😂😂