Interesting fact, healthcare trauma coordinators use media outlets like X as investigative tools to see what happened to their patients before they arrive to the ER. So please always post that freak accident caught on camera and tag it, you help save lives!
🤯Three (!!!) new papers today in @ScienceMagazine on the application of generative AI for the de novo design of peptide/HLA binding molecules! Completely unique 3D structure and binding mode compared with natural TCRs and TCR mimics! Links to papers 👇
"my mission is to spread the word to the public and funders alike that, just like pre-diabetes, there is such a thing as ‘pre’-cancer which is an untapped opportunity to intervene and save lives."
Read a new Profile 👇 https://t.co/sB0svfLR9d
Chimeric antigen receptor T-cell (CAR-T) therapy, already approved for certain blood cancers, is generating excitement in early tests against autoimmune diseases. Designed to wipe out a whole class of immune cells, the treatment holds promise but comes with potentially serious risks.
Learn more: https://t.co/xe1gea7lYC @NewsfromScience
From carbon dioxide to starch—no plants required.
In Science, researchers developed a cell-free method of synthesizing starch from CO2 and hydrogen using a combination of chemical catalysts and a carefully selected set of enzymes. Learn more: https://t.co/22Feuebuum #ScienceMagArchives
A new Science #Immunology study describes an antibody-based alternative treatment for B cell non-Hodgkin #lymphoma that boosts #NaturalKillerCell antitumor activity in preclinical models without causing serious toxicities. @CIML_Immunology@InnatePharma
https://t.co/ZrkBnYnWsw
In a distracted world, the most underrated leadership skill is listening.
144 studies, 155k people: Good listeners have deeper bonds and better results. We feel valued, and they get smarter.
Great leaders are devoted learners. A key to learning is to listen more than you talk.
A thread on some of the most surreal trains and beautiful train rides
1. The Mauritanian iron ore train, one of the world's longest and heaviest, spans up to 3 km, travels 704 km, and has 200-300 carriages, each weighing up to 84 tons
Biggest medical discoveries of the week (🧵)
#1 - Evo: generative AI for biology
From scratch, Evo could:
Design a functioning CRISPR-Cas enzyme (top right figure)
Predict gene essentiality at genome-wide scale (bottom left figure)
Generate genome-length DNA sequences, encoding a diverse set of proteins (though not quite able to support life! - bottom right figure)
Study: https://t.co/Ux2QPRwlO3
Understanding the difference between Standard Deviation (SD) and Standard Error (SE) is crucial for accurate data interpretation. SD measures the variability within your data, indicating how spread out the individual data points are from the mean.
In contrast, SE measures the uncertainty around the sample mean as an estimate of the population mean. It reflects the precision of the mean, with SE decreasing as the sample size increases, making your estimate more reliable.
The relationship between SD and SE is given by the formula: SE = SD / √(sample size). While SD remains relatively constant with larger samples, SE diminishes, highlighting the reduced uncertainty in the mean estimate.
A common mistake in research is using the “±” notation without specifying whether it refers to SD or SE, leading to potential misinterpretation of the data. Clear distinction is essential for transparency and accuracy in reporting.
Key Takeaways:
• Use SD to describe data variability.
• Use SE to indicate the precision of the mean.
• Always specify which measure you are reporting.
Specialized fat cells—thermogenic adipocytes—burn excess calories to generate heat.
A #SciencePerspective reviews the process, known as adipose thermogenesis, and how it may hold the key to battling diseases like type 2 diabetes. https://t.co/n0UDAw32OK #ScienceMagArchives
Adult human brains have between 86-100 billion neurons and every single one is unique - like snowflakes! ❄️
In this 3D rendering by our #ElectronMicroscopy team, we see 3 different shapes incl. (from left to right) a basket cell, tufted excitatory cell, and a Martinotti cell.
This is how AI games will be made…
No world map, real time rendering of what you need to see.
It may also be how our simulation is rendered… the world may not exist except when you observe it.