Janeth Ochoa Birrueta

Scientist in training in the Crouch Lab @UCSF | Brain organoid enthusiast | Otra Latina más en el mundo de la ciencia 👩🏻‍🔬

[Aparna Bhaduri @BhaduriLab]

Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote upper layer cortical neurogenesis through NRXN1-mediated contacts with outer radial glia. https://t.co/cmdprwV7ch

[𝐁𝐈𝐆 𝐌𝐎 … @JaYunnaMonae]

All federal funding for grants, loans and programs will be paused as of 1/28/25 at 5pm. This means that NO MORE FUNDS WILL BE DISBURSED. Some of the funding areas affected include:

1. Head start and federally subsidized daycares
2. STUDENT FINANCIAL AID AND GRANTS
3. SNAP BENEFITS/ Food Stamps
4. Non-profits that receive federal funds or grants
5. ACA Health Insurance (premiums may rise)
6. Education programs funded federally i.e. After School programs, Special Ed
7. Medical Research/Cancer/Infectious Diseases
8. MEDICAID (Medicare and Social Security may be soon).
9. Affordable Housing and Section 8 payments
10. Foreign Aid
11. Clinics

This list is NOT exhaustive. I pray that those who voted for this especially for RACIST ideologies now understand that CLASSISM doesn’t care about your race. NOT ONE PERSON who benefits from and who is in need of federal funding/assistance is exempt from this. JESUS, BE A FENCE!

~Cheryl D. Moore~

[Sergiu P. Pasca @Sergiu_P_Pasca]

The @CSHL conference on neural stem cell models and human development coincides this year with the publication of a consortium effort in @Nature.

This article outlines a framework for experiments with #organoids, #assembloids #transplantation from quality control and integrity of human pluripotent stem cells to characterizing and manipulating neural cells in vitro and in vivo.

Link to the open access article below

[Endothelial Cell News @endothelialnews]

Scientists generated human-induced venous #endothelial cells (iVECs) by manipulating cell-cycle dynamics via the retinoic signaling pathway.

🧫 iVECs with the TIE2 mutation recapitulate the pathogenesis of venous malformations.

💬 More here: https://t.co/m23a4kn9jh

[Elizabeth Crouch, MD/PhD @ElizabetsCrouch]

Thank you @LabRaleigh. I’m excited about the future of “Vascular Neuroscience” for both discovery and therapies. I look forward to new options for these patients and unmasking of vascular cell states in cancer @UCSFstemcell @UCSFNeo

[Elizabeth Crouch, MD/PhD @ElizabetsCrouch]

Brain vascular biology is heating up! 🔥Exciting new vascular subtypes are emerging via transcriptomics. Functional studies on the horizon! 🌅@UCSFGradDiv @UCSFstemcell @NatRevCardiol https://t.co/QvXrnuSDSo

[Endothelial Cell News @endothelialnews]

Investigators showed that a feedback loop ➰ between H3K9la and #HDAC2 in endothelial cells drives #VEGF-induced #angiogenesis.

They found that the H3K9la levels were upregulated in #endothelial cells in response to VEGF ⚡ stimulation.

@GenomeBiology | https://t.co/xkCT4csPvg

[Elizabeth Crouch, MD/PhD @ElizabetsCrouch]

Congrats @LDiafos for a fantastic 🤩presentation @hersheydevbraininjury conference on vascular cell changes after #germinalmatrixhemorrage more to come! 👀👏@UCSFNeo @UCSFstemcell

[Nico Gagelmann @NicoGagelmann]

Tumor immunology, simplified😅

[Sergiu P. Pasca @Sergiu_P_Pasca]

An interesting assembloid model in @CellStemCell

https://t.co/dTtkqYiVDx

[Aparna Bhaduri @BhaduriLab]

Very excited to present a @bioRxiv paper from our lab on our human organoid tumor transplantation (HOTT) system to study glioblastoma! This work was led by the very talented project scientist Dr. Weihong Ge + exceptional graduate student @RyanKan20 (1/18)
https://t.co/49K8h887wQ

[Latinas in STEM @LatinasinSTEM]

Dropping some small consejitos by Latinas in STEM. This month, we have Dr. Daisy Rosas Vargas. She is a science communicator and education consultant.

#LatinasinSTEM #Latinas #STEM #ConsejoTuesday

[Elizabeth Crouch, MD/PhD @ElizabetsCrouch]

Hopefully my journey as a #physicianscientist is helpful to others on or considering this path. Featuring #Crouchlab members @kwp_futuremdphd @LDiafos @Scientist_Jan @EdwardV_MSc @Jayden_M_Ross & Neos @Kpkrame @JingshingWu @UCSFNeo @UCSFPediatrics @nicupodcast

[Hao Yin @HaoYin20]

Cultured Cells in standard plastics can actually be Hypoxic & lactate-producing

It matters how High the medium level is in your dish/well!🤯
The medium as liquid phase creates a steep oxygen gradient......

33~50 µL per 96-well make your cells happily oxygenated (Have you added more than that?🤪)

What a mind-blowing, critical finding!👹

"Lowering medium volumes increases de novo lipogenesis and mitochondrial glucose oxidation in adipocytes" 😈

Sorry that I will read this carefully again for my next SMC project, and follow the Table EV1 (red framed👇)

@joycelyntsi @DPhaz @embojournal 2024
https://t.co/hTOoLhbDIy

[Elizabeth Crouch, MD/PhD @ElizabetsCrouch]

We are hiring an SRA! Could you be the next awesome member of our team? 🤓🥼🔬🧬🧫#neurovascular #organoid #germinalmatrixhemorrhage

https://t.co/3IZ5BU2yLk

[Kauê Machado Costa @kmcostalab]

Someone once told me that every lab is a journey that starts in an empty room(s). Today I got mine. So it begins 🧠🐀

[Caroline Hu @HuWantsToKnow]

Seeking scientist volunteers! Want to practice science communication and help author a ✨comic✨ about your research? I need collaborators for this spring's cohort of SciComm & Comics art students! Please share widely. #STEMeducation #Science #sciart

[Giorgia Quadrato @GiorgiaQuadrato]

Thrilled to start off the new year with a new lab publication, titled: "Human Cerebellar Organoids with Functional Purkinje Cells", led by the exceptionally talented PhD candidate @AlexanderAtami1 @CellStemCell https://t.co/MdHBx5SBf0 🧵 1/11

[Elizabeth Crouch, MD/PhD @ElizabetsCrouch]

Pleased to post our @NatureProtocols pub profiling human vasculature using transcriptomics and organoids 🧬🧠🧫. https://t.co/yUGwXoNNTD Building off previous work in 🐭brain, we describe human specific procedures for #flowcytometry #neurovascular #organoids & #transcriptomics

[Hao Yin @HaoYin20]

Vascular cell perturbations in #AlzheimersDisease

Human brain Vessel snRNAseq
9 Case+8 Ctrl
>140k cells

#Pericyte subtype
Transporter-vs Matrix-pericyte

AD🧠loses regional heterogeneity of vascular cell transcriptome

@andcyang @wysscoray @Nature 2022
https://t.co/U09USglnhz