Serhan Turunç

[News from Science @NewsfromScience]

For decades, biology textbooks have enshrined a simple rule: DNA is made by copying a template. After one enzyme unzips a DNA double helix into separate strands, another called a polymerase builds a complementary sequence, base by base, for each strand. Presto: two copies of the original DNA.

But new research into how bacteria defend themselves from viruses now shows this synthesis rule isn’t absolute.

Now, a team describes a bacterial enzyme that synthesizes DNA without a nucleic acid template, using its own structure as a guide.

Learn more: https://t.co/bpVgr0KMdR

[Sergio Cruz-León @SergioCruzLeon1]

Excited to share our pre-print on the molecular architecture of heterochromatin in human cells🧬🔬
w/ @jpkreysing, Johannes Betz,Turoňová lab, @MarinaLusic, Hummer lab, @Beck_Laboratory, @MPIbp
🔗 Preprint here: https://t.co/0tTxZcu0Vz

[Nature Portfolio @NaturePortfolio]

Rock and dust samples brought back from the near-Earth asteroid Bennu contain organic matter, including amino acids and all five DNA and RNA nucleobases, according to two papers in @NatureAstronomy and @Nature.
https://t.co/jsPwhx0GlT
https://t.co/TYF0D5O2Ly

[NASA @NASA]

Remember when we brought pristine asteroid samples back to Earth? The first big science is in!

The samples suggest that the early solar system had widespread conditions and ingredients for life. Here's how we know: https://t.co/PHPjpaWgWs

[The Nobel Prize @NobelPrize]

The 2024 #NobelPrize laureates in chemistry Demis Hassabis and John Jumper have successfully utilised artificial intelligence to predict the structure of almost all known proteins.

In 2020, Hassabis and Jumper presented an AI model called AlphaFold2. With its help, they have been able to predict the structure of virtually all the 200 million proteins that researchers have identified. Since their breakthrough, AlphaFold2 has been used by more than two million people from 190 countries. Among a myriad of scientific applications, researchers can now better understand antibiotic resistance and create images of enzymes that can decompose plastic.

Read more about their story: https://t.co/nWxcZs6wqC

[Eric Betzig @Eric_Betzig]

Relationship between chromosomes (orange) and the mitotic spindle (green) in four stages of cell division, as seen by Bessel Beam plane structured illumination microscopy https://t.co/Z5NRQOoi4q

[Özgür Taşcı @tscozgur]

Ben Özgür TAŞCI. Bursa’da bir devlet okulunda matematik öğretmeni olarak çalışıyorum. Uludağ Üniversitesi matematik öğretmenliğini bölüm birincisi olarak, İstanbul hukuk fakültesini 3,40 ortalamayla bitirdim. Geçen yıl idari yargı hakim adaylığı sınavında Türkiye 2. Si, bu yıl idari yargı hakim yardımcılığı sınavında Türkiye 3. Sü oldum. Ortalama 1,5-2 dk süren mülakatlarda, mülakatlarım güzel geçmesine rağmen eleniyorum.
Görüyorum ki bir zamanlar mağdur olduklarını ileri sürenler, şimdi kendileri yeni mağdurlar yaratıyor, kul ve kamu hakkına giriyorlar.
Ben ülkemi seviyorum, bu ülkeye ömrüm fırsat verdikçe de hizmet etmeye devam edeceğim. Meslekte 10. Yılımı çalışan bir öğretmen olmama ve tüm zorluklara rağmen görevimi yeni atanmış bir öğretmen edasıyla azimle ve gayretle yapmaya çalışıyorum. Bundan sonraki süreçte ise mensubu olmaktan gurur duyduğum Türk milleti adına Anayasaya, kanunlara ve hukuka uygun olarak adil kararlar vermek, adalet sancağını taşımak istedim. Ancak görüyorum ki bizler, bizleri yönetenlerin zerre kadar umurlarında değiliz.
En zoruma giden ise çaresizlik. Her cuma namazında hutbede Nahl 90. ayet okunurken acı çekiyorum, evlatlarım bana hocam hakimlik d��şünüyor musunuz diye sorduklarında onlara “mülakat diye bir gerçek var çocuklar” diyemeyip gözlerindeki ışığı söndürmemek için susmaktan acı çekiyorum.
Adalet mülkün temelidir. Ekonomi başta olmak üzere yaşanan tüm sorunların çözümü liyakat ve adaletten geçer. Devlet adil olduğu sürece güçlüdür şiarıyla tüm bu olanları kamuoyunun bilgisine sunuyorum. Takdir sizindir.
@yilmaztunc @TBMMresmi @Haberturk @ntv @SONTV_ @TVAdalet @alicanuludag @ibrahimuslu55 @birincimucahit @cengizaksan @nedimsener2010 @Gurbuz_KARAKUS @trhaber_com @mahfiegilmez @DrGunerSonmez

[Seyit Kale / Kale Lab @KaleLabBiophys]

🎉NEWS🎉
Kale Lab has won computing time from EuroHPC
for chromatin-related rare diseases research! PhD student Serhan Turunç might be the first
Turkish user of #MareNostrum5!
🙏🙏@EuroCC_project, @EuroHPC_JU,
@TrubaUlakbim, @EuroCC_Turkey, @Tubitak,
@ibgmerkezi @RareDiseasesIBG

[Kurumizaka Lab @KurumizakaLab]

Our new paper about the structural mechanism by which RAD51 assembles at double-stranded DNA break sites on chromatin has been published in Nature!
https://t.co/bR8Oxjv8RP
#CryoEM #Nucleosome #RAD51 #DNArepair

[Genetic Engineering & Biotechnology News @GENbio]

For the first time, scientists have engineered an enzyme that can break the stubborn man-made bonds between silicon and carbon that exist in widely used chemicals known as siloxanes, or silicones. Learn more: https://t.co/xzM3C19c6g

[Serhan Turunç @Serhan_Turunc]

Presented my poster yesterday, had a great discussion with wonderful scientists. Thanks for all the feedback and amazing organization! #EMBOComp3D @EMBOevents

[Nature Biotechnology @NatureBiotech]

The UK medicines regulator approves the first therapy using CRISPR gene editing. @VertexPharma and @CRISPRTX's Casgevy will treat the blood conditions sickle-cell disease and β-thalassemia #NBTNewsBeat https://t.co/sqHXP1byNT

[Seyit Kale / Kale Lab @KaleLabBiophys]

Kale lab is on the news!!! 🚨🚨🚨

See the article about "A new look at the molecular machinery of cell division"

Link is down below 👇
https://t.co/W1VUgO2PUc

[eLife - the journal @eLife]

This “thought-provoking” paper exploits new #CryoET tools to examine the state of chromatin in situ, finding that nucleosomes in baker’s yeast cells are different from those in test tubes. https://t.co/yWYmaYyPR7

[Serhan Turunç @Serhan_Turunc]

@IOzanBb @BioDiscoveryHub Bir söke un etmez bence 😃

[Nucleosome papers 📚 NucPosDB database @Nucleosome_Bot]

The CENP-A nucleosome: where and when it happens during the inner kinetochore's assembly https://t.co/IiboWth5WR

[Trends in Biochemical Sciences @TrendsBiochem]

Available online - the Review "The #CENPAnucleosome: where and when it happens during the inner kinetochore’s assembly" from @KaleLabBiophys and colleagues.

#histonevariant #mitosis #CCANcomplex

Read it here 👉 https://t.co/7HpBhLfIoO

[Seyit Kale / Kale Lab @KaleLabBiophys]

State of the lab, July 2023. Thank you @EMBO @EMBO_YIP and @Tubitak for your continued support.

[microscopic images. @microscopicture]

death of a single cell

[Feng Zhang @zhangf]

Delivery of therapeutic molecules is a major bottleneck for treating a wide range of diseases. Today we describe a new modality for delivering proteins based on an engineered contractile injection system @nature https://t.co/eIAn8MW6jN