Shivani Sachdev, PhD

👩‍🔬 Assistant Professor @ACTREC_TMC @CRI_ACTREC | Postdoc @NIDDKgov @NIH | Chemical Biology & Pharmacology | Editor @BrJPharmacol | Views my own

[Shivani Sachdev, PhD @ShivDoesScience]

Honoured to begin this new chapter at @CRI_ACTREC @ACTREC_TMC alongside such an incredible group of faculty members 😊

[Cancer Research Institute - ACTREC @CRI_ACTREC]

Hearty welcome to @ShivDoesScience
Our new faculty addition!!!
Shivani is a chemical biologist whose lab focuses on developing antibody-engineering platforms combined with peptide chemistry to probe cell surface protein function in cancer.
@biopatrika

[Shivani Sachdev, PhD @ShivDoesScience]

@abandopa Happy Diwali 🪔

[Shivani Sachdev, PhD @ShivDoesScience]

Happy Diwali from the Sachdev Lab 🪔

Lab is decorated, disco light is on, the cells have been told to fend for themselves. Priorities.✨🧫🙏🏻

[Shivani Sachdev, PhD @ShivDoesScience]

Nanobody expression, Halloween night🎃🧫💀🥼
22:15 — Two personnel present, identification not possible.
23:50 — Asked if kanamycin was added. Response: a nod.
01:00 — Personnel no longer present. Flask present.
08:00 — Yield unexpectedly good.

[ACTREC-TMC @ACTREC_TMC]

Proud moment for @ACTREC_TMC!

Congratulations to our Director @pankajch37, on being named a 2026 Highly Ranked Scholar – Lifetime in Oral Cancer by @ScholarGPS, placing him among the top 0.05% worldwide. 👏

[Shivani Sachdev, PhD @ShivDoesScience]

Celebrated Pragya's birthday today! 🎂

She keeps our pipelines running, from single-cell seq through to target validation, and still finds time to humour me when I show up asking if we can just try RFdiffusion for protein binder discovery 🎯🤖

[Pramesh CS @cspramesh]

Every day at Tata Memorial Hospital @TataMemorial, we see patients facing their cancer with incredible courage. But for many families, the struggle goes beyond the disease — the cost of treatment and just getting by can be overwhelming.

This Tata Mumbai Marathon @TataMumMarathon, I’m asking you to join me in doing something about it.

You don’t have to run a marathon to make a difference. A donation, however small, can help a patient who really needs it.

Let’s come together to make sure that no one has to give up because they can’t afford treatment for their cancer.

Please contribute, share this post, and help us reach more people. Every bit counts. ❤️

To contribute to the cause, please click the link here: https://t.co/HsHQY0pToZ

#TataMumbaiMarathon #TataMemorialHospital

[Shivani Sachdev, PhD @ShivDoesScience]

@shruthy_suresh @arpan_parichha @Ankesh1406 @shruthy_suresh we’ll miss you! Was looking forward to seeing you again but next time…

[Shivani Sachdev, PhD @ShivDoesScience]

Very much looking forward to the meeting! We had a lovely visit to IGIB in May—now it’s our turn to host you!!! 🥰@arpan_parichha @shruthy_suresh @Ankesh1406

[Cancer Research Institute - ACTREC @CRI_ACTREC]

@CRI_ACTREC is excited to host colleagues from @IGIBSocial for the @ACTREC_TMC - IGIB Conclave happening on 19th November in @ACTREC_TMC !! Looking forward to foster new collaborations and fruitful interactions!!
@biopatrika

[Shivani Sachdev, PhD @ShivDoesScience]

Throwback to our IGIB @IGIBSocial visit!Two packed days of science between #ACTREC and #IGIB, covering CAR-T therapy, antibody engineering, single-cell RNA seq, computational protein binder design, disease models, and much more! 🥳👩‍🔬

[Shivani Sachdev, PhD @ShivDoesScience]

Little late to post this, but @CRI_ACTREC basic and clinical science talks were excellent!!!
Seeing how things work in the hospital, from diagnosis through treatment, and where the tools we build could apply, is a very different exercise from thinking about it from the bench🧑‍🔬🩺

[Rohan Khadilkar @RohanKhadilkarr]

We are looking forward to host this awesome line up of speakers for our @EMBO @EMBOevents global lecture series on Nov 23rd in @ACTREC_TMC @CRI_ACTREC @biopatrika
Promises to be a day of fabulous science and interactions! Can't wait!!

[Shivani Sachdev, PhD @ShivDoesScience]

After weeks of troubleshooting the FPLC, the column is finally back in 🥳
Nothing like getting back to protein purification to lift the week 💉🦙
Smiles in the lab at last, though it feels too soon to celebrate🤞@CRI_ACTREC

[Jakob Höppner @jakobhoeppner]

Check out our latest study, now published in @CellChemBiol

We investigated how two closely positioned mutations in helix 8 of the PTH receptor cause brachydactyly type E through distinct molecular mechanisms.

Many thanks to all our collaborators!

[Shivani Sachdev, PhD @ShivDoesScience]

First peptides synthesised in the Sachdev lab @CRI_ACTREC, by Zeel, our first PhD student👩‍🔬✨ Took a bit of doing to get here, and there’s plenty more to come, but today it counts as a win 🧪🥳

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”

[Cancer Research Institute - ACTREC @CRI_ACTREC]

Excited to host 4 global stalwarts from the fields of hematopoiesis, stem cell biology & cancer in the EMBO Global Lecture Series on November 23rd!

[Shivani Sachdev, PhD @ShivDoesScience]

@saip_pydi @jclinicalinvest Congratulations!!!

[Shivani Sachdev, PhD @ShivDoesScience]

Big thanks to the amazing team at Sachdev Lab for such a fun lab outing — making #nanobodies all week and trekking to waterfalls on the weekend, you all bring the same energy everywhere. Also grateful to be @ACTREC_TMC working with such a talented group 🦙⛰️

[Tata Memorial Centre @TataMemorialCtr]

Research drives innovation at Tata Memorial Centre.

In July, our faculty and researchers published 47 peer reviewed articles, advancing cancer research, scientific discovery, and evidence based patient care.

Every publication brings us closer to the future of cancer care.

[Allison Fitzgerald, MD, PhD @allisonoconn]

Today I learned heavy chain only antibodies (aka no light chain) exists but only in camelids (camels, llamas, alpacas) and sharks.