🚨 New publication out in @jbiolchem!
We show how FNBP4 inhibits FMN1-mediated actin dynamics, revealing key regulatory mechanisms of non-diaphanous formin. Grateful to @Maiti_SP for his guidance and @ANRFIndia for funding!
🔗 https://t.co/MghTOKv53v
#ActinCytoskeleton@iiserkol
Our new paper in @PLOSBiology introduces IntAct-U-ExM enabling isoform-specific imaging of actin at nanoscale across yeast, mammalian cells & primary neurons. Fabulous work spearheaded by @anubhav_dhar along with an amazing team! #actin#UExM
https://t.co/6kkrhfb6hz
Very pleased that after a rigorous (and lengthy) review process, our paper visualizing how myosin generated forces modulate actin filament structure for mechanosensitive recogntion by α-catenin has appeared in @Nature
https://t.co/gzEziWL8aB
Kaptin, discovered 30 yrs ago in Prof. Bruce Alberts’ lab by Prof. Elaine Bearer. https://t.co/UlC8uTwsjz
Thrilled that we identified it as a WD-repeat protein and mapped its F-actin–binding residue.
Thanks @radha751@Maiti_SP@DBT_NCCS_Pune
🔗 https://t.co/Z3EmeEzc4k
Proud to share our second publication on PIST, now out in @ACS_Infectious
“GP63 Alters the Macrophage Golgin160-Associated PIST Distribution by Reducing Caspase3 Expression during Leishmania major Infection.”
🔗 https://t.co/zbsrmKfaAP
1/1🚨Excited to share novel findings on Kaptin !!!
Together with @Maiti_SP (IISER Kolkata) and @radha751 (NCCS Pune), KPTN binds barbed end of actin filaments, slows elongation, stabilizes the actin network, and is a WD-repeat protein for the first time https://t.co/2eUUc7Pi8O
Thanks to everyone who stopped by my poster at #ASCB2024! I'm excited to connect with more researchers in the field. #cellbiology#research @CellBio2024 @EMBO
📢 New preprint!
FNBP4 inhibits non-diaphanous formin FMN1-mediated actin nucleation, processive capping & bundling activities. We also uncovered FNBP4's nuclear-specific role in modulating actin dynamics!
Thanks to @Maiti_SP https://t.co/hvx3dkl5BG