Simpson Lab @UWMedicine

Illuminating keratinocyte cell biology @DermatologyUW to understand epidermal differentiation/tissue homeostasis and how they are compromised in skin disease.

[Simpson Lab @UWMedicine @SimpsonLabUW]

Thrilled to share the 1st @SimpsonLabUW research publication online @JCI_insight. We generated a pre-clinical model of Darier disease, a rare genetic skin blistering disorder that I see in my clinic and for which there are no FDA-approved therapies (1/7)
https://t.co/fsyxEh2sWE

[Simpson Lab @UWMedicine @SimpsonLabUW]

Starting the migration to the other place, same handle @SimpsonLabUW …hoping to find the old #sciencetwitter and #dermtwitter crowds.

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Proud of med student Rafael Homer whose summer research project @SimpsonLabUW @DermatologyUW won 2nd place in the @uwsomwwami Wyoming site poster competition! Rafael also won a travel award to attend the Western Medical Research Conference & was chosen for an oral presentation🤩

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

New paper from @SimpsonLabUW @DermatologyUW is online @JCI_insight🍾We found ERK hyperactivation disrupts cell-cell adhesion in epidermis, linked this pathway to both drug-induced & spontaneous Grover disease & identified MEK inhibition as a novel therapy: https://t.co/Ko48RnTxNp

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Great lunch @SimpsonLabUW⁩ ⁦@DermatologyUW⁩ for lots of celebrating including Arti’s birthday 🥳 More good news to share soon now that I’m out from under the cloud of this R01 submission ���‍💨📝 ✅🤞

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Very proud of Akshata for representing @SimpsonLabUW @DermatologyUW at the @UWISCRM Fall Symposium. She did a great job at her 1st poster session explaining her work developing quantitative methods to assess our model of #HaileyHailey disease, a rare #skin #blistering disorder.

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

We were sad to bid farewell to Rafael Homer, rising 2nd-year med student (left), who joined @SimpsonLabUW @DermatologyUW for the summer from the Laramie, Wyoming campus of @uwsomwwami @UWMedicine. Thanks for your work on a project to improve our understanding of #Darier disease.

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Grateful for an @american_skin1 grant to support our work @SimpsonLabUW @DermatologyUW to understand how #keratinocytes mature via #autophagy to form the outer skin layers and how this is disrupted in thick, scaly #psoriasis plaques (image from DermNetNZ). https://t.co/2oLD1kL9yl

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Thank you to @UpliftingAth Researcher Connection Program for providing a travel award for @JessicaLeeAyers from @SimpsonLabUW @DermatologyUW to attend the #Darier & #HaileyHailey Disease Symposium @SocInvestDerm mtg. Her poster was well-attended and she gave an outstanding talk!

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

@SimpsonLabUW has grown over the summer so we needed two selfies🤳🤩Very proud of this group of curious & collaborative scientists all doing great work to understand skin regeneration and @RareDiseases in #dermatology while teaching me to be a better researcher, teacher & mentor.

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Fun happy hour to celebrate CJ @johnsonch20 departing @DermatologyUW to return to clinics @uwsomwwami. Special thanks to @PssfMsrf for supporting his 1-year fellowship @SimpsonLabUW. Look fwd to sharing his awesome work @ASCBiology in Dec and submitting his 1st-author paper soon!

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

So proud of @UWM3D PhD student @JessicaLeeAyers (photo #2) for her awesome lightning⚡️talk @UWISCRM Symposium on her thesis project modeling #HaileyHailey disease, a rare genetic skin blistering disorder w/o any FDA-approved therapy. Making @SimpsonLabUW @DermatologyUW shine! 🤩

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Loved seeing @SimpsonLabUW members Afua Tiwaa & @uwsomwwami med student CJ Johnson do a great job explaining their projects @UWISCRM Symposium. Congrats to CJ on his poster prize! They're gearing up for oral presentations in Dallas @SocInvestDerm mtg in just 2 wks!🧫🔬🤩 #ProudPI

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Fantastic talk by @DrWoappi imagining new horizons in #regenerative #medicine for #skin. Impressive work addressing wounds which have HUGE impact on quality of life & healthcare💰 Thanks to @UWBioE for giving me a slot for a chat. Hope to see you @SocInvestDerm as a rising⭐️soon!

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Excited to share our paper @theJIDJournal w/@JennyNathans @JShendure reviewing how DNA barcoding can map cell lineages in skin development/cancer & how CRISPR-based DNA Typewriter can be used as a molecular tape-recorder to log biological signals in vivo.
https://t.co/Tx6XBEnSNo

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Just 1 mo until our inaugural #Darier & #HaileyHailey Symposium convenes scientists, clinicians & advocates for these rare diseases w/o any FDA-approved drug (appealed another Rx denial for patient today). Join us pre @SocInvestDerm mtg in Dallas Tue 5/14! https://t.co/OdWprACr1d

[Simpson Lab @UWMedicine @SimpsonLabUW]

Inspiring spotlight from @TODAYshow on the innovative work of our lab neighbors @UWMedicine.

[UW Medicine @UWMedicine]

Dr. Nora Disis was recently interviewed by @TODAYshow correspondent @kristendahlgren as one of the top cancer researchers in the country as Dahlgren turns her focus towards The Pink Eraser Project, which will continue connecting other cancer researchers. https://t.co/oP3htLFVFF

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Thanks again to @LEOFondet for investing in @SimpsonLabUW @DermatologyUW @UWMedicine to fund our work on Hailey-Hailey disease, a rare blistering disorder. Look fwd to our inaugural symposium on Darier & Hailey-Hailey @SocInvestDerm mtg on May 14--join us! https://t.co/dlzHGGtV7t

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Looking forward to attending @the_asci meeting in Chicago in April. I am very grateful for their support of the clinician-investigator pipeline through this award program that provides networking and career development opportunities for early-stage physician-scientist PIs.

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Excited our new grp focused on the rare genetic blistering disorders #Darier & #HaileyHailey Disease will partner w/@Pachyonychia for 2 awesome symposia before @SocInvestDerm 2024 mtg. We aim to bring together researchers & clinicians to kindle translational synergy in our field!

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Lots of fun @FlatstickPub⛳️ for @SimpsonLabUW holiday party! Not pictured is the scorecard🤫Looking forward to working with this wonderful group of scientists @DermatologyUW in 2024. Happy holidays!