Simran Sandhu

MD Candidate | Working on representation,justice, and vulnerability | 🇮🇪 🇨🇦

[Simran Sandhu @SimranSandhu17_]

I am excited to share that I have matched to Family Medicine at Toronto Metropolitan University!

Beyond grateful for all of the support and mentorship I have received throughout my journey, to make this possible.

Looking forward to what’s ahead!

#carms2026 #TMUmatch

[Simran Sandhu @SimranSandhu17_]

@BreastDense @DavidLimMD @WCHResearch @GRASPtweets @ASCO @ConquerCancerFd @LobularBCA @LobularIreland @ELBCAdvocates @News_IACR @EACRnews @AACR Such a pleasure to connect with @BreastDense! I look forward to working with you! ☺️

[David W. Lim @DavidLimMD]

@LobularIreland @JAMouabbi @SimranSandhu17_ @ASCO @elbcc @ELBCAdvocates @Galway_Research @BCResearchIre @UCDCancerTrials Happy to share that @SimranSandhu17_ also received a 2024 @GRASPtweets Advocate Choice Award for this abstract, which will be discussed at the @GRASPtweets Poster Walkthrough.

[Jason A. Mouabbi MD @JAMouabbi]

5 #ILC Abstracts will be presented at #ASCO24 as Poster Presentations on Sunday June 2nd at 9:00 AM - 12:00 PM

1️⃣ Racial disparities in presentation and survival for lobular breast cancer
Presenter: @SimranSandhu17_ (University of Galway, Ireland); @DavidLimMD
Data: SEER database study with 38,769 ILC patients
Findings: Black women present with more advanced disease; Asian women are younger at diagnosis. 5-year overall survival for Black women is worse.
Takeaway: We must bridge the gaps in care for ILC patients across different races.

2️⃣ The multiomic tumor microenvironment landscape of ILC
Presenter: @JAMouabbi (MD Anderson Cancer Center) @BostonGeneCorp @Hensley1552
Data: MxIF on 2,139,084 cells from FFPE whole-slide tissues
Findings: Detailed multiomic analysis reveals 40% of ILC samples are immune enriched (potential for immunotherapy) and 30% are highly vascularized (potential for anti-angiogenesis therapy).
Takeaway: Many ILC patients may benefit from immunotherapy or anti-angiogenesis regimens.

3️⃣ Neoadjuvant targeted therapy in HER2-mutant lobular breast cancer
Presenter: Laura Kennedy (Vanderbilt-Ingram Cancer Center); @AriellaHanker @CarlosArteagaMD
Background: 10% of ILCs have HER2 (ERBB2) mutations, linked to ET resistance and worse prognosis.
Study: NCT05919108, Phase II trial for 30 patients with Stage I-III ILC and HER2 mutation, receiving letrozole + neratinib for 6 months pre-surgery.

4️⃣ Transcriptomic analysis of cAMP/PKA/CREB signaling in ILC
Presenter: @Susruthapn (Washington University School of Medicine); @oesterreichs
Data: RNA-seq from three large breast cancer databases
Findings: Up-regulation of cAMP/PKA/CREB signaling in ILC compared to NST/IDC.
Takeaway: Unique signaling pathway in ILC could lead to novel therapeutic targets.

5️⃣ Clinical-pathological characteristics and multigene assay risk scores in ILC
Presenter: Young-Won Lee (University of Ulsan College of Medicine, Seoul, Korea); @AsanMedicalCtr
Data: Retrospective analysis of 238 ILC cases
Findings: Predictive factors for ODX recurrence score in ILC differ from IDC.
Takeaway: Need for ILC-specific risk prediction tools.

#bcsm #EndCancer #ILC @LobularBCA @LobularBCUK @LobularIreland @lobbccanada @elbcc @double_whammied @lbhutcheson @OncoAlert @ASCO @VJOncology @OncBrothers @OncData @Keira_OncData

[Gavin Preston, M.D. @GavinPrestonMD]

"The good physician treats the disease;
the great physician treats the patient who has the disease."
Sir William Osler.

[Simran Sandhu @SimranSandhu17_]

Very grateful for your mentorship @DavidLimMD ! Looking forward to attending ASCO!

[OncoDaily @oncodaily]

Really proud of my mentee Simran Sandhu for getting her abstract accepted for poster presentation at ASCO24 - @DavidLimMD
@SimranSandhu17_ @WCHospital @WCHResearch @ASCO

#ASCO24 #Cancer #OncoDaily #Oncology #WomensCollegeHospital

https://t.co/HmhWhNTOh5

[Barack Obama @BarackObama]

Affirmative action was never a complete answer in the drive towards a more just society. But for generations of students who had been systematically excluded from most of America’s key institutions—it gave us the chance to show we more than deserved a seat at the table.

In the wake of the Supreme Court’s recent decision, it’s time to redouble our efforts.

[Hockey Night in Canada: Punjabi @HkyNightPunjabi]

(English) For Simran Sandhu being the only girl on an all boys team for almost a decade was a journey filled with trials, tests, and triumphs.

She's now using her experience to help young girls achieve their goals. 🏒 @AmritG reports #NGWSD

[Women's College Hospital @WCHospital]

To learn more about #BreastReconstruction surgery and meet others who have been through it, register for our free, virtual workshop: https://t.co/TujuVJAYuf #EveryWomanEveryChance

[David W. Lim @DavidLimMD]

It was a pleasure meeting @SimranSandhu17_, our @WCHResearch summer student, and giving her a tour of our beautiful @WCHospital.

Simran will be studying our outcomes after breast surgery & #breast reconstruction. @DrJohnSemple @tdcil @DavidUrbachMD @DrRulanParekh @jemd1 @UofTGSx

[Rulan Parekh @DrRulanParekh]

First batch of summer @WCHResearch #Students started today- excited to see #diverse #womeninSTEM. This is the future of #science 🙌🙌 @hannnnnahseo @sarahqureshii @lau_carr @jayshaw29 @lade_abeji @WCHIndigenous @simonevigod @DavidUrbachMD @WCHospital @RicharLisa @DrLisaRobinson