Before you jump on the nattokinase train like what seems to everyone else it’s important you know how and why it works
Nattokinase is a p-glycoprotein inhibitor
P-gp is the body’s cellular "bouncer” and nattokinase temporarily disables it
This means that compounds that would normally be pumped out are now free to pass through the cell and enter systemic circulation
It allows target molecules to accumulate in higher concentrations inside the cells and tissues than they normally would
How this can be a bad thing
If you are taking a medication or supplement alongside a P-gp inhibitor, your liver and gut stop pumping the excess out
When P-gp is inhibited, substances that have absolutely no business being in your central nervous system can cross the BBB and accumulate in the brain, leading to neurological side effects, lethargy, confusion, or neurotoxicity
We don't just ingest pure nutrients and clean supplements, our food, water, and environment contain trace heavy metals, pesticides, plasticizers, and microbial toxins.
Normally, if you ingest a trace environmental toxin, P-gp in your intestinal lining immediately recognizes it as a foreign threat and pumps it right back into the bowel to be excreted in stool.
If P-gp is locked in the "off" position, your gut loses its ability to filter these out, allowing a much higher percentage of daily environmental toxins to pass directly into your systemic circulation and burden your liver and kidneys.
By allowing molecules to bypass the initial gut defense and enter systemic circulation, you alter the kinetics of how your body processes everything.
The burden shifts entirely to your phase I and phase II liver detoxification pathways and kidney filtration. If these downstream systems are already working hard, the sudden flood of highly bioavailable compounds can create a metabolic bottleneck
Nattokinase is highly effective at preventing clots because it acts as a potent fibrinolytic enzyme, meaning it directly binds to and cleaves fibrin, the protein mesh that forms the structural backbone of a blood clot.
Beyond directly dissolving existing clots, it simultaneously breaks down plasminogen activator inhibitor 1 (PAI-1), a compound that normally suppresses the body's natural clot-clearing mechanisms.
By combining this direct clot-shredding action with the optimization of the body's intrinsic defenses, it significantly improves overall blood fluidity and circulation.
Whether the risk is worth the reward depends entirely on what else is going into your body and your specific cardiovascular goals.
For a completely clean, unmedicated protocol, maybe the risk profile is generally very low but the calculus changes completely the moment other pharmaceuticals or heavy supplement stacks are introduced.
To run nattokinase in a safer way (if I were to take it) I would isolate its ingestion by taking it on an empty stomach at least two hours away from all other supplements, medications, or food.
Ensure your protocol is completely free of pharmaceutical blood thinners or narrow-index cardiac medications to eliminate dangerous bioavailability spikes.
And maintain a clean, low-toxin low vitamin A dietary baseline to minimize the systemic absorption of environmental impurities while the intestinal barrier's defenses are reduced.
this article is from 2015. modafinil was created in the 70's. it's been meticulously studied since the 80's.
to this day, not one person has died from it.
air force pilots, doctors, students, entrepreneurs use it to enhance performance
it's still CRIMINALLY underrated.
🚨🚨 La planta de Artemisa podría destruir el 98% de las células cancerosas en solo 16 horas...
Impactante informe de salud está reavivando el debate después de que estudios con compuestos de artemisa mostraran la destrucción de hasta el 98% de las células cancerosas en solo 16 horas...
🦠🦠Artemisinina y el cáncer.
• Mecanismo de acción: Las células cancerosas suelen tener concentraciones muy altas de hierro para facilitar su rápida división. La artemisinina reacciona con este hierro intracelular, provocando un estrés oxidativo intenso y la formación de radicales libres que destruyen específicamente las células tumorales mediante procesos como la apoptosis y la ferroptosis...
• Estado de la investigación: Aunque existen numerosos estudios preclínicos (en laboratorios y animales) con resultados positivos, la evidencia clínica en humanos es todavía limitada. No se han completado ensayos clínicos a gran escala que confirmen su eficacia y seguridad total en pacientes oncológicos.
• Tipos de cáncer estudiados: Se ha investigado su efecto en diversos tipos, incluyendo el cáncer colorrectal, de pulmón, de tiroides, de ovario y de próstata. En algunos casos, se ha observado que puede actuar como un "quimiosensibilizador", ayudando a que otros tratamientos de quimioterapia sean más efectivos.
• Seguridad y efectos secundarios: Generalmente se considera segura en dosis controladas, pero puede causar toxicidad hepática, náuseas y vómitos. Es esencial monitorear la función del hígado durante su uso
Dr. Berg.
🚨 TWO BULGARIANS JUST KILLED THE STREAMING INDUSTRY.
It's called Stremio + Torrentio. You get 4K content from Netflix, Disney+, Hulu, and HBO Max — combined — for free.
Here's how it works.
Stremio is the player. Polished interface. Works on Windows, macOS, Linux, Android, iOS, and TV. Install it once and it looks like any premium streaming app.
Torrentio is the addon. Add it to Stremio in one click. It scrapes every major torrent provider simultaneously and delivers the best available stream straight to your player. 720p, 1080p, 4K. You choose the quality. It finds the source.
→ No account required
→ No subscription
→ Works on every device
→ 4K and HDR supported
→ Subtitles built in
Netflix can't touch this. There is no central server to seize. No company to sue. No domain to kill. It lives on your device and pulls from the open internet.
The entire streaming industry runs on one assumption. That you'll keep paying $70/month instead of spending 5 minutes on GitHub.
That assumption just died in Sofia, Bulgaria.
MIT License. 100% Open-source.
Get the addon here: https://t.co/WxWS91oTrk
70 CHROME EXTENSIONS THAT TURN YOUR BROWSER INTO A SUPERPOWER.
1. uBlock Origin Lite
Blocks every ad, tracker, and malware domain on the internet.
2. SponsorBlock
Auto-skips sponsor segments inside YouTube videos.
3. Honey
Auto-applies the best coupon code at checkout on any site.
4. Bitwarden
Free password manager that replaces LastPass and 1Password.
5. Dark Reader
Turns every website on the internet into dark mode instantly.
6. ClearURLs
Strips tracking junk from every link you copy or click.
7. Tampermonkey
Runs custom scripts that modify any website however you want.
8. Wayback Machine
Instantly opens the archived version of any dead webpage.
9. Privacy Badger
Learns and blocks invisible trackers without any setup.
10. I Still Don't Care About Cookies
Auto-dismisses every cookie banner on the internet.
11. Vimium
Lets you navigate any website using only keyboard shortcuts.
12. OneTab
Collapses 50 open tabs into one clean list instantly.
13. Tab Suspender
Freezes inactive tabs to free up massive amounts of RAM.
14. Session Buddy
Saves and restores entire browsing sessions across devices.
15. Toby
Visual tab manager that organizes your browser like a dashboard.
16. Workona
Groups tabs into workspaces by project or task.
17. Momentum
Replaces the new tab page with a clean focus dashboard.
18. Marinara Pomodoro
Free pomodoro timer that lives in your browser toolbar.
19. StayFocusd
Blocks distracting websites after a daily time limit.
20. Forest
Plants a tree that dies if you leave your focus session.
21. JSON Viewer
Auto-formats and color-codes raw JSON in your browser.
22. WhatFont
Tells you the exact font, size, and weight of any text.
23. ColorZilla
Picks any color from any webpage with an eyedropper.
24. React Developer Tools
Inspects React component trees directly inside the browser.
25. Vue.js devtools
Inspects and debugs Vue apps directly inside the browser.
26. Wappalyzer
Reveals the entire tech stack any website is built on.
27. CSS Peeper
Inspects fonts, colors, and styles without opening DevTools.
28. Lighthouse
Audits any webpage for speed, SEO, and accessibility.
29. Web Developer Toolbar
Adds a full toolbar to disable scripts, validate HTML, and more.
30. Octotree
Adds a file tree sidebar to every GitHub repository.
31. Enhancer for YouTube
Adds volume boost, custom speed, screenshots, and more.
32. YouTube NonStop
Kills the "Are you still watching?" popup forever.
33. DeArrow
Replaces clickbait thumbnails and titles with honest crowdsourced ones.
34. PocketTube
Organizes YouTube subscriptions into clean folders.
35. Channel Blocker
Permanently hides specific channels from search and recommendations.
36. YouTube Auto HD
Forces YouTube to always play in the highest resolution available.
37. Shortcuts for YouTube
Adds keyboard shortcuts YouTube should have built in.
38. Unhook
Removes the YouTube home feed, Shorts, and recommendations.
39. NoScript
Blocks JavaScript by default and only runs what you whitelist.
40. Decentraleyes
Stops your browser from pinging Google and Cloudflare on every page.
41. Cookie AutoDelete
Wipes cookies the second you close a tab.
42. CanvasBlocker
Stops websites from fingerprinting your browser via canvas API.
43. Malwarebytes Browser Guard
Blocks phishing sites, scams, and tech support fraud in real time.
44. Loom
Records your screen and webcam and shares it via instant link.
45. Awesome Screenshot
Captures full pages, annotates, and records your screen.
46. GoFullPage
Captures any entire webpage as a single tall image.
47. Grammarly
Catches typos and grammar mistakes as you type anywhere.
48. LanguageTool
Open source grammar checker that replaces Grammarly Premium.
49. DeepL Translate
Translates any selected text into 100+ languages instantly.
50. Save to Notion
Saves articles, tweets, and pages straight into your Notion workspace.
51. Pocket
Saves articles to read later beautifully on any device.
52. Mercury Reader
Strips ads and clutter for distraction-free article reading.
53. Speechify
Listens to any article in natural-sounding human voice.
54. Reader View
Removes ads and clutter for clean reading mode on any site.
55. ImTranslator
Translates any selected text into 100+ languages instantly.
56. Highlighter
Highlights text on any webpage and saves it forever.
57. Hypothesis
Annotates any webpage like a PDF with public or private notes.
58. Wikiwand
Redesigns Wikipedia into a clean modern reading layout.
59. Liner
Saves article highlights and organizes them by topic automatically.
60. Notion Web Clipper
Clips articles, videos, and tweets directly into Notion.
61. Mendeley Web Importer
Saves research papers to your reference library in one click.
62. Anki Web Importer
Turns any webpage into flashcards instantly for studying.
63. Bypass Paywalls Clean
Unlocks paywalled articles on 100+ news websites.
64. Control Panel for Twitter
Hides trending, ads, and the "For You" tab on Twitter.
65. Refined Twitter
Cleans up the timeline and restores old Twitter features.
66. Reddit Enhancement Suite
Adds infinite scroll, tagging, and dozens of Reddit upgrades.
67. Old Reddit Redirect
Forces every Reddit link to open in the old clean layout.
68. LinkedIn Sales Navigator Killer
Strips ads, promoted posts, and "people you may know" spam.
69. Hide LinkedIn Engagement
Hides likes and reposts to break the dopamine loop.
70. News Feed Eradicator
Replaces social media feeds with a motivational quote.
We’re aware of a new YouTube issue occurring today and have released a fix for it: https://t.co/bGYBG3nxAi
To get the fix as soon as possible, manually update the browser’s ad blocker. Here’s how to do it on each platform 👇
Desktop: Go to Settings > Shields > Content filtering and click the “Update lists” button
iOS: Go to Settings > Shields & Privacy > Content Filtering and click the “Update Lists” button
Android: Go to Settings > Brave Shields & privacy > Content filtering and click the “UPDATE” button
After that, reload your YT tabs.
If you go to Brave://components on Android and desktop after updating, you should now see “Brave Default Adblock Filters” at Version 1.0.1989 or later and “Experimental ad blocker” at Version 1.0.84 or later.
Let me know if you’re still having issues!