Just published online first & presented #IDWeek2023
Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial @EdQian@toddrice_ICU & colleagues
https://t.co/xA5SHNamml
Can never review this topic enough - “the water of life” as one of my mentors called 0.9 NS. Fluid choice usually engenders strong opinions, some of my favorite discussions. I’ve always been an #LR guy for general use.
Source: @COREIMpodcast#MedTwitter
Why use hydrocort over dex in septic shock? When to prophylax (and for what?) When to stop steroids (and how?)
I had a lot of ??? around steroids which led to this CORE IM episode, which really was a huge team effort given steroids = used for everything
I have grown to ❤️IV iron
This is a nice review on the when, why and the how to fill the iron tank
@JosephineCool1@FreedoBaggins
https://t.co/uvwZCAIaWt
1/10
CASE
76 yo M with Waldenstrom's macroglobulinemia (WM; IgM 3000-5000 mg/dL), treated in past with rituximab, dexamethasone and cytoxan, presents with iron deficiency anemia. Colonoscopy and OGD negative. Capsule study shows multiple jejunal AVMs.
Ring any bells?
1/THREAD
Ever wonder why fluoroquinolones increase the risk of tendon rupture?
It seems so random that a whole class of antibiotics could cause tendon injuries, but the risk is real.
#medtwitter#tweetorial
A short 🧵 on my 3️⃣-prong approach to rounding with resident teams in the MICU…
I emphasize 3️⃣ themes to the residents and fellows:
1️⃣ Clinical care
2️⃣ Education
3️⃣ Development
#MedTwitter#MedEd
1/9
Hematologists are comfortable diagnosing and treating Fe deficiency.
However, many of us are outside our comfort zone when it comes to chronic kidney disease.
Why?
Because the diagnostic criteria and indications for treatment are so vastly different, even antithetical.
1/3
Hb or Hct?
I prefer using Hb in patients with anemia because oxygen carrying capacity is limiting, and Hct in patients with polycythemia because blood viscosity is limiting.
For those at equipoise, it's dealer's choice, though I like to think positively and use Hb. 😉
❗️SGLT2i were described a long time ago.
✅They are now popular drugs to treat type 2 diabetes, heart failure, and chronic kidney disease.
Want to know more? Time for a 🧵
1/20
You are seeing a patient with irresistible urge to move legs. How do you go from history to diagnosis?
The diagnostic process involves:
1. Patient representation
2. Diagnostic framework
3. Differential diagnosis
4. Illness scripts
1/14
🤔Why does it take weeks for the radiographic evidence of pneumonia to clear?
Patients often feel better DAYS after starting treatment.
And yet the chest x-ray takes WEEKS to return to normal.
Why the delay?
1/4: 🚨 “Do you think it’s ok to give this patient zofran? What about their QTc?” 🚨
#Tweetorial on QT prolonging drugs and torsades de pointes (TdP) 🧵
#MedEd#MedTwitter
@WrayCharles asks, and he receives (2 years later)!
He asked for a 1-pager to help residents present effective chalk talks. With the help of the inimitable @Gurpreet2015 & @AcadMedJournal, I present to you our humble attempt to fulfill his ask.
Find it👇
https://t.co/ip7JbB2ses