@X

[@X @MoreXGrok]

Findings?

Diagnosis?

[@X @MoreXGrok]

Procedure bleeding risk guidance.

https://t.co/MDo3BFHLyV

[@X @MoreXGrok]

@schowardjd @GoHealio Nice

[@X @MoreXGrok]

2.5-month-old baby girl

7-day hx of multiple lesions

2-day hx of poor activity, decreased appetite, and respiratory distress

Born to a healthy 28-year-old woman after an uncomplicated pregnancy and had appeared healthy until 1 wk ago.

Thoughts?

[@X @MoreXGrok]

Read here 👇

https://t.co/wRFYsFh8kQ

[@X @MoreXGrok]

Blueberry muffin syndrome

Had been reported to be a manifestation of either dermal erythropoiesis or neoplastic infiltrations

Dermal erythropoiesis may be caused by

*congenital virus infections, such as rubella, cytomegalovirus, coxackie virus B2, and parvovirus B19,

*or by severe hemolysis associated with Rh incompatibility, blood group incompatibility, hereditary spherocytosis, and twin–twin transfusion syndrome

Among the neoplastic diseases with the presentation of blueberry muffin babies,

*neuroblastoma was the most common, whereas rhabdomyosarcoma, Langerhans cell histiocytosis, and leukemia were less frequently reported.

[@X @MoreXGrok]

𝗖𝗲𝗳𝗼𝘁𝗲𝘁𝗮𝗻

●Aside from nitroimidazoles like metronidazole, perhaps the second most-recognized antimicrobial class associated with disulfiram-like reactions is cephalosporin antibiotics,

*specifically those that contain a methylthiotetrazole (MTT) substituent (e.g., cefotetan, cefoperazone, cefamandole).

****

●Cefotetan is a second-generation cephalosporin antibiotic used for treating a wide range of infections, including

*intra-abdominal, skin, bone, respiratory, and urinary tract infections.

●It can also be used for prophylaxis in gastrointestinal surgeries and

*contains a unique side chain that may lead to rare side effects like prolongation of prothrombin time and a disulfiram-like reaction.

[pharmacy by asim @pharmed0929]

🦠 𝗖𝗲𝗳𝗼𝘁𝗲𝘁𝗮𝗻 can cause a 𝗱𝗶𝘀𝘂𝗹𝗳𝗶𝗿𝗮𝗺-𝗹𝗶𝗸𝗲 𝗿𝗲𝗮𝗰𝘁𝗶𝗼𝗻 due to its ability to 𝗶𝗻𝗵𝗶𝗯𝗶𝘁 𝗮𝗹𝗱𝗲𝗵𝘆𝗱𝗲 𝗱𝗲𝗵𝘆𝗱𝗿𝗼𝗴𝗲𝗻𝗮𝘀𝗲, an enzyme involved in alcohol metabolism.

✅ This 𝗿𝗲𝗮𝗰𝘁𝗶𝗼𝗻 𝗶𝘀 𝘀𝗶𝗺𝗶𝗹𝗮𝗿 𝘁𝗼 𝘁𝗵𝗮𝘁 𝗰𝗮𝘂𝘀𝗲𝗱 𝗯𝘆 𝗱𝗶𝘀𝘂𝗹𝗳𝗶𝗿𝗮𝗺, a drug used to deter alcohol consumption. Patients taking cefotetan 𝘀𝗵𝗼𝘂𝗹𝗱 𝗯𝗲 𝗮𝗱𝘃𝗶𝘀𝗲𝗱 𝘁𝗼 𝗮𝘃𝗼𝗶𝗱 𝗮𝗹𝗰𝗼𝗵𝗼𝗹 𝗱𝘂𝗿𝗶𝗻𝗴 𝗮𝗻𝗱 𝗳𝗼𝗿 𝗮𝘁 𝗹𝗲𝗮𝘀𝘁 𝟳𝟮 𝗵𝗼𝘂𝗿𝘀 𝗮𝗳𝘁𝗲𝗿 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 to prevent this reaction.

🎯 𝙔𝙤𝙪 𝙘𝙖𝙣 𝙫𝙞𝙨𝙞𝙩 𝙢𝙮 𝙔𝙤𝙪𝙏𝙪𝙗𝙚 𝙘𝙝𝙖𝙣𝙣𝙚𝙡 𝙛𝙤𝙧 𝙖𝙢𝙖𝙯𝙞𝙣𝙜 𝙘𝙡𝙞𝙣𝙞𝙘𝙖𝙡 𝙥𝙝𝙖𝙧𝙢𝙖𝙘𝙤𝙡𝙤𝙜𝙮 𝙫𝙞𝙙𝙚𝙤𝙨:https://t.co/JZKmKuhP4z

[@X @MoreXGrok]

@Tayma_mhierat01 Yes

[@X @MoreXGrok]

Diagnosis?

[@X @MoreXGrok]

@vlb_BT Yes.

[@X @MoreXGrok]

@knowocean84 Yes.

[@X @MoreXGrok]

@lalar_an Nice.