Stephanie Johnson

Scientist at the interface of biology, physics, and computation; currently a Senior Software Manager at EikonTx. Special fondness for genome structure-function.

[Stephanie Johnson @StephL_Johnson]

Coders with cross-functional expertise in probability, or in optics - join our growing software team working at the interface of computation, microscopy, math, and science, and use your skills to discover new therapeutics for human health! https://t.co/q2WiPjXR4b

[Stephanie Johnson @StephL_Johnson]

Eikon is hiring! Come join an interdisciplinary team of software engineers and computational scientists working to extract biologically meaningful information from super-resolution microscopy images: https://t.co/4MUz4uAZfH

[Stephanie Johnson @StephL_Johnson]

Final paper from my postdoc with Geeta Narlikar finally out!

[Nucleosome papers 📚 NucPosDB database @Nucleosome_Bot]

ATP hydrolysis coordinates the activities of two motors in a dimeric chromatin remodeling enzyme https://t.co/GJEjBTHfnS

[Adi Hanuka @AccAdkoo]

Come work with me and our amazing cross-functional team! @EikonTX we’re looking for a talented applied ML software engineer who’s interested in doing extremely multidisciplinary work involving biology, chemistry, physics and a lot of machine learning. https://t.co/UPwqetnggd

[Stephanie Johnson @StephL_Johnson]

And software!

[Eikon Therapeutics @EikonTX]

🔬Drawn to the frontier of scientific challenges? Seeking a new challenge and a mission-driven culture? We're looking for endlessly curious people interested in working at the intersection of chemistry, engineering, computation, and biology. Learn more: https://t.co/UQMqbpIwQm

[Eikon Therapeutics @EikonTX]

Announcing our $517.8M Series B & the expansion of our executive team! We’re honored to have the support of incredible investors & proud to work with them as we pioneer novel drug discovery based on tracking real-time movement of proteins in living cells. https://t.co/RKbfPCkhHV

[Eikon Therapeutics @EikonTX]

We are pleased to announce that Eikon Therapeutics, Inc. has received an award from Endpoints as "One of Biopharma's Most Promising Startups in 2021"

https://t.co/CNIZIrY6Pk

[Stephanie Johnson @StephL_Johnson]

Software@Eikon is hiring! Come join a world-class team of scientists and engineers using advanced #Microscopy techniques to open new avenues in #drugdiscovery : https://t.co/AK7OlovVVK https://t.co/XZVUtFqaKQ

[Tjian + Darzacq Group @TjianDarzacq]

Alec Heckert and @DahalLiza’s paper on a new package for SPT analysis is on @biorxivpreprint now - They describe a toolkit to infer distributions of diffusion coefficients from
SPT data without prior knowledge of the # of underlying states. https://t.co/3DPjj3OvTo

[Eikon Therapeutics @EikonTX]

It's a big day at Eikon! Today we're introducing our company, welcoming our new CEO, Roger Perlmutter, MD PhD, former President, Merck Research Labs, and announcing our Series A funding round of $148M. (1/4) https://t.co/s39jQ5oH8B

[Stephanie Johnson @StephL_Johnson]

Eikon is hiring! Come join a world-class group of scientists and engineers opening up new avenues in #drugdiscovery with live-cell #SuperResolution microscopy. My team (software) has two openings for proficient Python coders: https://t.co/M8Fw2ydYx6

[Stephanie Johnson @StephL_Johnson]

My final paper from my postdoc is up on bioRxiv! Of all my work with Geeta, this was always the crowd-pleaser (won a Best Poster Prize at an ASBMB meeting some years ago). Single molecule FRET-enabled mechanistic dissection of an ISWI-family chromatin remodeler.

[bioRxiv Biophysics @biorxiv_biophys]

ATP hydrolysis coordinates the activities of two motors in a dimeric chromatin remodeling enzyme https://t.co/5o3D9qMT1x #biorxiv_biophys

[Cees Dekker @cees_dekker]

Two wonderful lists!

> 12 tips for engaging with biologists, as told by a physicist https://t.co/QpaeR0QjHL

>13 tips for engaging with physicists, as told by a biologist:
https://t.co/kTRg43GNyw

I recognise a lot...

[Gene Regulation @generegulation]

It's interesting to hear about chromatin biology from analysts of Goldman Sachs https://t.co/o7EuZk6hX0 According to them, investments in "chromatin drugs" would be ~$40 billion over the next two decades. BTW, they wisely don't use the word "epigenetic" :) CC @EpgntxEinstein

[biohub @biohub]

Open source software is 🔑 to science. Many of the packages, libraries + applications crucial to biomedicine are built by researchers who volunteer their time + effort to make these tools available. We’re excited to announce support for #opensource tools https://t.co/VtAS7DIWMZ

[Biophysical Journal @BiophysJ]

Submit to our new special issue "Multiscale Modeling of Chromatin: Bridging Experiment with Theory" edited by Tamar Schlick with guest editors Thomas Bishop, Lars Nordenskiöld, and Andrzej Stasiak. For more information on how to submit, see here: https://t.co/SUFhNFVicv

[Stephanie Johnson @StephL_Johnson]

A fun and thought-provoking review, considering the #evolution of #chromatin to understand chromatin mechanisms and functions.

[Gene Regulation @generegulation]

Old cogs, new tricks: the evolution of gene expression in a chromatin context [review by Paul Talbert, Michael Meers & Steven Henikoff; 200 references] https://t.co/ymql44BSPb Evolutionarily ancient role of chromatin and how it has diversified for evolutionarily recent functions

[Stephanie Johnson @StephL_Johnson]

Great review by @FreddyMValencia and @CKadoch on #chromatin and chromatin modifiers (including chromatin remodeling enzymes!) as therapeutic targets in #Cancer

[𝗔𝗹𝗳𝗿𝗲𝗱𝗼 𝗠 𝗩𝗮𝗹𝗲𝗻𝗰𝗶𝗮, 𝗣𝗵𝗗 🔬 @FreddyMValencia]

Thanks for the shout out @alexia_zz!

Excited to start off the year with our review in @NatureCellBio on chromatin regulation and cancer. With a broad scope, we hope this is useful to the community and those interested in learning more about the topic!

Huge thanks to @CKadoch!

[Stephanie Johnson @StephL_Johnson]

Our paper on nucleosome-bound chromatin remodeler structures by cryo-EM is out on bioRxiv!

[Nathan @ngamarra91]

https://t.co/wZbobUyZrZ

[Stephanie Johnson @StephL_Johnson]

It was great fun to be part of this work by @MagdaGebala and Dan Herschlag - changed the way I think about #chromatin structure and compaction!

[bioRxiv Biophysics @biorxiv_biophys]

Ion counting demonstrates a high electrostatic potential of the nucleosome https://t.co/S9foMAOC1X #biorxiv_biophys