This article provides a contemporary review of carbohydrate metabolism during exercise, factors affecting its exogenous oxidation rates and sport-specific research, before presenting an updated and more nuanced model to guide carbohydrate personalisation strategies for endurance athletes.
1/ Why do muscles atrophy with aging and disuse?
Is it because each tiny little myofibril gets smaller… or is it because we lose myofibrils?
In our new study, we addressed this in humans and mice. https://t.co/J7nEk1r6P2
Full breakdown of the findings in this thread 👇
Thrilled to share our new @ScienceAdvances paper where we provide evidence that mechanical stimuli drive skeletal muscle growth through TWO distinct mechanisms—and use BONCAT to visualize where the growth occurs. Take a look: https://t.co/Hk6SpXK5aJ
Mitochondrial Permeability Transition in Skeletal Muscle Phenocopies Muscle Alterations seen in Cancer Cachexia and other Wasting Conditions | bioRxiv https://t.co/0okLS7ZrWb
Honored to share our lab’s preclinical work on NMJ structure and function after ACL injury with leaders in football medicine at the 2025 Isokinetic Conference. Grateful to @LindseyLepley, @UMKines, and @footballmed for the opportunity and support!
Effects of Exercise Training on Mitochondrial & Capillary Growth in Skeletal Muscle
Larger Training Volumes (⬆️training frequency/week +⬆️training weeks) & Higher Training Intensities👉greater increases in mitochondrial content & VO2max
#muscle#exercise
https://t.co/Emj9VwjupF
Testosterone/androgen receptor antagonizes immobility-induced muscle atrophy through Inhibition of myostatin transcription and inflammation in mice
https://t.co/09PWsLYF8N
PoWeR elicits intracellular signaling, mitochondrial adaptations, and hypertrophy in multiple muscles consistent with endurance and resistance exercise training | Journal of Applied Physiology | American Physiological Society https://t.co/XIlVbM2IoV
The Mitochondria‐Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age - Mitchell - Aging Cell - Wiley Online Library https://t.co/7wsu9nyGJF
Exercise as Mitochondrial Medicine: How Does the Exercise Prescription Affect Mitochondrial Adaptations to Training? | Annual Reviews - https://t.co/3CExCMQRIe
Nice work by colleagues here!
Adaptive time course of the skeletal muscle proteome during programmed resistance training in rats
https://t.co/0nZOR4OMZg
Excited that our review: "Exercise as Mitochondrial Medicine: How Does the Exercise Prescription Affect Mitochondrial Adaptations to Training?" in ANNUAL REVIEW OF PHYSIOLOGY with @MitoPsychoBio & @matt_lee1 is now Online: https://t.co/pTwnCAW3nc