Thomas Schmidt

LOA-Chief Consultant. Professor for Surgical Oncology. Cologne University. HPB, UGI Surgery, Metastasic Microenvironment Research. Passionate Surgeon-Scientist

[Thomas Schmidt @SurgeonSchmidt]

Very happy to share that our manuscript is now online. Here we show the role of fibroblasts in colorectal cancer liver metastasis.
Thank you to the whole team, especially to Ying @ShenYin17010393 and Xiaohong. Great collaboration with Alba @diz_lab

https://t.co/H0LkYTWaCV

[Giovanni Marchegiani @Gio_Marchegiani]

📣 It's out! The PACT-21 CASSANDRA is on @TheLancet

🔵 Preoperative mFOLFIRINOX vs. PAXG for stage I–III PDAC

👑 PAXG prolonged median EFS (16 vs. 10 months) with similar adverse events

🧐 New standard of care !?

https://t.co/95MN9q3Y4l

[Thomas Schmidt @SurgeonSchmidt]

@MarkarSheraz @NDSurgicalSci @ISDE_net @Augishealth @EAES_eu @young_esde Congrats Sheraz. Very well deserved.

[Steven D Wexner MD, PhD @SWexner]

The role of length of oral resection margin and survival in esophageal cancer surgery after neoadjuvant therapy: A retrospective propensity score-matched study https://t.co/vBAeuj90Lm Thank you @SurgeonSchmidt for your excellent OPEN ACCESS contribution to @SurgJournal

[Ville Sallinen @villesallinen]

New impact factors are out!
Selected surgical journals 👇
JAMA Surg 15.7
BJS 8.6
Ann Surg 7.5
JACS 3.8
BJS Open 3.5
EJSO 3.5
ASO 3.5
Surgery 3.2
DCR 3.2
Colorec Dis 2.9
HPB 2.7
Tech Coloproct 2.7
Hernia 2.6
Scand J Surg 2.5
Surg Endosc 2.4
WJS 2.3
J GI Surg 2.2
Langenbeck’s 2.1

[BJS Open @BjsOpen]

Surgical and multimodal treatment of metastatic oesophageal cancer: retrospective cohort study
➡️https://t.co/5KBdva8sJk

This retrospective single-centre cohort study included 235 patients with metastasized oesophageal cancer. A comparison was conducted of patient outcomes after resection alone, multimodal therapy including surgery, chemotherapy alone, any other therapy without surgery, or best supportive care as a treatment for metastasized oesophageal cancer. Resection or multimodal therapy including surgery resulted in the best overall survival in the total cohort and in subcohorts of patients with metachronous solid-organ metastases, with metastases in the liver, lung, or adrenal gland, or with a single metastasis.

👏👏👏Karl Knipper, Julian Lemties, Thaddaeus Krey, Su Ir Lyu, Naita M Wirsik, Lars M Schiffmann, Hans F Fuchs, Florian Gebauer, Wolfgang Schröder, Felix C Popp, Alexander Quaas, Hans A Schlößer, Christiane J Bruns, @SurgeonSchmidt

#SoMe4Surgery #MedTwitter #SurgEd #Surgery @me4_so @for_surgery @for_surgeons @modern_surgeon @surggpt @BJSAcademy @BJSurgery @young_bjs @juliomayol @JJEarnshaw @OUPMedicine #some4UGI #uppergi #esophagealcancer @ISDE_net @Augishealth @roux_group @T4UGIS #ESDE @young_esde @lucasgoense @SMantziari @JessieAElliott @MarkarSheraz

[BJS Open @BjsOpen]

Hyperthermic intraperitoneal chemotherapy in colorectal cancer
➡️https://t.co/MLFKFNFTdb

This is a large multicentric global study combining a number of large national peritoneal surface oncology databases from three continents (39 centres) for evaluating the use and choice of hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with peritoneal metastasized colorectal cancer undergoing cytoreductive surgery. It is the largest study in the field of peritoneal surface oncology for colorectal cancer with crude survival analysis in over 2000 patients and propensity score matched survival analysis in over 1300 patients. This study found that oxaliplatin-based HIPEC resulted in superior overall and recurrence-free survival compared to mitomycin C-based HIPEC—a finding which persisted after propensity score matching. However, high-dose mitomycin C protocols resulted in improved survival, and a dose–response relationship between low-dose and high-dose HIPEC treatment regardless of protocol drug used was further discovered.

👏👏👏@OMaxFisher, Chris Brown, Jesus Esquivel, Stein G Larsen, Winston Liauw, Nayef A Alzahrani, David L Morris, Vahan Kepenekian, Isabelle Sourrouille, Frédéric Dumont, Jean-Jacques Tuech, Cécilia Ceribelli, Béranger Doussot, Olivia Sgarbura, Mohammed Alhosni, Francois Quenet, Olivier Glehen, @CashinPtr, Peritoneal Surface Oncology Group International (PSOGI), Nordic Peritoneal Oncology Group (NPOG), American Society for Peritoneal Surface Malignancy (ASPSM) and BIG-RENAPE Groups

#SoMe4Surgery #MedTwitter #SurgEd #Surgery
@me4_so @for_surgery @for_surgeons @modern_surgeon @surggpt @BJSAcademy
@BJSurgery @young_bjs @juliomayol
@JJEarnshaw @OUPMedicine #colorectalsurgery #colorectalcancer @FightCRC #StepUp4CRC #HIPEC

[Marc Besselink @MarcBesselink]

Can video assessment of surgical skills using OSATS (score 12-60) during #Robot #Pancreatoduodenectomy predict the risk of POPF?

153 PJ videos @DPCG_official
OSATS <49 ➡️ 43.6% POPF
OSATS ≥49 ➡️ 15.8% POPF

https://t.co/n6uvxWoezw

[Daniel Hartmann @HartmannDaniel5]

I strongly recommend applying here. The chances are very good. We on the EDS board particularly welcome applications from surgeons in training.

[Thomas Schmidt @SurgeonSchmidt]

Our Computational Surgical oncology team is on track ✅

Jin-On Jung published that random survival forest is the optimal machine learning algorithm to predict survival in resectable gastroesophageal cancer ❗

https://t.co/uWQkh4dK7x

More to come 🔥…https://t.co/jx8YhWxbiE

[Thomas Schmidt @SurgeonSchmidt]

Our Computational Surgical oncology team is on track ✅

Jin-On Jung published that random survival forest is the optimal machine learning algorithm to predict survival in resectable gastroesophageal cancer ⏫

More to come 💡

@uniklinik_hd @UKKoeln

https://t.co/uWQkh4dK7x

[Thomas Schmidt @SurgeonSchmidt]

Prediction of postoperative complications after esophagectomy 🟰 neuronal network ✅
Other prediction models did not perform equally for Clavian Dindo ≥ IIIa 🚫
Jin-On Jung in my team of Cologne Computational Surgical Oncology
@UKKoeln @BJSurgery
https://t.co/AU1mAsJXxq

[Thomas Schmidt @SurgeonSchmidt]

https://t.co/tVWIjwAQtd

[Langenbeck's Archives of Surgery @LAOS1860]

#bernierecommends 👀
Perioperative CTx with 5-FU, leucovorin, oxaliplatin, and docetaxel (FLOT) for esophagogastric adenocarcinoma:
10 years real-life experience from a surgical perspective
https://t.co/YteVI0PqkH

Leila Sisic et al.
@HenrikNien
@beatpetemueller
@SurgeonSchmidt

[Thomas Schmidt @SurgeonSchmidt]

@plitsah @Fischblog @BMauschen @Sander_Lab @RicardoLange4 @dgfn_ev @gunnar_heine @BuckerGunnar @oegnephro You should have this checked and most likely make an appointment with a nephrologist

[Mohamed Abu Hilal @Abuhilal9Abu]

Last touches on https://t.co/lwZthaWWoQ 110 agreed statements (57 for lap and 53for robotic MIPS) .17 best video candidates . 8 endorsing societies &a great faculty. Looking forward to seeing you in Brescia @poliambulanza @EAHPBA @IHPBA @SAGES_Updates @e_mips @MarcBesselink 🎉👍

[Marie-Louise Timcke @datentaeterin]

How gendered is the clothing offer for children? For our @SZ data analysis, we examined 20,000 shirts and shorts from @hmdeutschland, @Zalando and @aboutyou_com that they offer online for children under 10. The results show: Current children's fashion cements gender images. 🧵

[Shailesh V. Shrikhande @Shrikhande_SV]

@NawazUsmanDr @Manishbhandare4 @DrVAChaudhari @IHPBA @AHPBA My pleasure and honour 😎I know the feeling. I myself owe a lot to Markus Buchler and Helmut Friess @surgery_hps @JorgKleeff @doctor_felix @ProbstPascal @SurgeonSchmidt

[Marc Besselink @MarcBesselink]

Outcome #Pancreatic #Surgery during 1st 6 yrs of a nationwide 🇳🇱 audit?
In-hospital mortality after #pancreatoduodenectomy improved ✅ 4.1%➡️2.4% related to FTR 13.4%➡️ 7.4% although ⬆️ high-risk pts.
Impact biggest in high vol centers. Collaboration! https://t.co/TpYZtKn4Vy

[Giovanni Marchegiani @Gio_Marchegiani]

🧪 Postoperative Hyperamylasemia (POH) adds value to FRS in predicting POPF 🐳

😱 50% of POH eventually develop POPF

😵‍💫 POH limits FRS predictive accuracy!!!

👉 POPF risk assessment is a dynamic process including FRS, POH and drain amylase 👈

https://t.co/SLlIMESeEJ

[Heidelberg Pancreatic Surgery (HPS) @surgery_hps]

#openaccess in @BJSurgery‘s August issue: Pancreatic surgery with or without drainage: propensity score-matched study https://t.co/oAHiQhJNkj @doctor_felix @KFKowalewski @HaneyCaelan @ProbstPascal @SurgeonSchmidt @markus_diener @beatpetemueller