SykesLabMGH

Understanding and developing therapy for the treatment of patients with hematologic disorders.

[Mass General Brigham Research @MGBResearchNews]

We're thrilled to introduce our next challenger of #BreakItDownForMe, David Sykes, MD, PhD!

Watch a sneak peek below to learn what he does when he isn't breaking down his [very complex] paper for us!

Watch the complete video: https://t.co/qzsGDprU8x

@SykesLabMGH

[SykesLabMGH @SykesLabMGH]

A huge team effort done in collaboration with friends at Karolinska Institute where we explored the underpinnings of metastatic renal cell carcinoma. https://t.co/9ixle5zR4z.

[SykesLabMGH @SykesLabMGH]

Please join me, along with my colleagues at the Mass General Cancer, at the upcoming Mass General Cancer Center Classical Hematology Review & ASH Highlights virtual CME on February 14-15. To view the agenda and enroll, click here: https://t.co/tRiNGXb4vG.

[Nick Mullen @NickMullen402]

Check out our new paper on combined targeting of de novo and salvage pyrimidine nucleotide synthesis for cancer treatment. This strategy dramatically improved survival in a highly aggressive, immunocompetent mouse model of PDAC.
https://t.co/mg72MGJPTa

[Nick Mullen @NickMullen402]

There needs to be a Red Zone equivalent for college football. They can just call it “Degeneracy”

[John H. Shin MD, MBA @JohnHShinMD]

Our latest is now @NatureComms! From OR➡️lab, we studied potential therapeutic targets at the molecular level using single-cell analysis of tumor cells from the kidney & spine. Go team! @baryawno @SykesLabMGH @ScaddenLab @KharchenkoLab @MGHNeurosurg

https://t.co/KeFExz4fg3

[SykesLabMGH @SykesLabMGH]

Hiring! Looking for a postdoctoral researcher. Project involving solid tumor bone marrow metastases. https://t.co/pC0876SPMV

[The Mansour Lab @Mansour_Lab]

Exciting new paper from the lab showing the impact of neutrophil precursors as a cellular therapy for invasive fungal infection in neutropenia.

https://t.co/XhTc7v8g7U

Our cover image for this JLB issue:

[SykesLabMGH @SykesLabMGH]

A very nice paper that marries cool chemistry and real biology from friend and colleague (last author) Jonathan Carlson. https://t.co/S1VZsZ52ur

[Udalova Lab - Genomics of Inflammation @UdalovaLab]

Today we're working with the Hoxb8 cells (immortalized myeloid progenitors that can be differentiated into neutrophils). Our PhD student @juls_sala is applying lentivirus CRISPR/Cas9 to Hoxb8 cells to study the functional regulators of neutrophil maturation and effector functions

[SykesLabMGH @SykesLabMGH]

#Hiring #research #Laboratory

Looking for research technicians to join our lab at the Massachusetts General Hospital!

https://t.co/pC0876AGyN

[SykesLabMGH @SykesLabMGH]

#Hiring | Looking for curious scientists who can spend 2+ years with us as research technicians working on rare disorders of the bone marrow! | https://t.co/c6WXBMxWw7

[Jake Rosenberg @JRosenbergMDPhD]

Excited to share our study of a patient with aplastic anemia, where a genetic diagnosis led to a successful targeted intervention, and new avenues of promising biology https://t.co/90V8QK5seb @MedCellPress.
🧵1/

[SykesLabMGH @SykesLabMGH]

The Sykes Lab is hoping to hire a research technician and post-doctoral fellow. Please check us out https://t.co/c6WXBMxWw7 if you are interested!

[APSA @A_P_S_A]

David Sykes MD PhD @SykesLabMGH @MassGeneralNews studies TEMPI characterized by Telangiectasias, ⬆️ Erythrocytosis, Monoclonal gammopathy, Perinephric fluid, Intrapulmonary shunting -> finds effective therapy. @ASH_hematology @katrinarmstrong https://t.co/qEfQnBsb40

[Prof Peter Hotez MD PhD DSc(hon) @PeterHotez]

To prepare for future pandemics we must support physician-scientists | ⁦@thehill⁩ many thanks ⁦@jennkwanMDPhD⁩ ⁦@DrEJBMD⁩ for the nice mention https://t.co/9fPGnfebpG

[SykesLabMGH @SykesLabMGH]

The Sykes Lab is hoping to hire a research technician and post-doctoral fellow. Please check us out https://t.co/c6WXBMxWw7 if you are interested!

[SykesLabMGH @SykesLabMGH]

@RHRLeBlanc @AaronGoodman33 Please let me know if you have seen a patient with TEMPI syndrome! @DavidBSykes

[SykesLabMGH @SykesLabMGH]

@AaronGoodman33 Thank you for your mention of the TEMPI syndrome! @DavidBSykes

[SykesLabMGH @SykesLabMGH]

@fabiopss @AaronGoodman33 Please have your colleague reach out to me if they have not already! We are trying to collect a database of all of the TEMPI syndrome patients in the world (up to 26 so far). Thank you. @DavidBSykes