Didier Soulat

Lover of illustration/BD, Microbiologist or/and Immunologist depending on the bug. Opinions are my own and not the views of my Institute or UKER

[Mike Sowden @Mikeachim]

OK, this is nuts.

In Sept 2023, geophysicists over the world started monitoring an odd signal coming from the ground under them.

It was recorded in the Arctic, then Antarctica - then everywhere, every 90 seconds, regular as a metronome - for NINE DAYS.

What the HELL?

1/

[Eric Topol @EricTopol]

Physical activity and the reduction of all-cause mortality, from 2 very large prospective cohorts
1. The relationship is non-linear, suggesting a threshold effect for many types of exercise as seen below

[Didier Soulat @Tazoul]

This is a collaborative work between many immunology labs of the @UniFAU. I hope that we can convince the community that our discovery is worth being published.

[bioRxiv Immunology @biorxiv_immuno]

Coxiella burnetii infects osteoclasts and alters their differentiation and function in a type IV secretion system-dependent manner https://t.co/lJk2z5Krpe #biorxiv_immuno

[David Sancho @SanchoLab]

💥 A gut microbe metabolite that drives #atherosclerosis?
Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol.
🧪 We show the pathway—and how to block it.
https://t.co/ZazBw50FFC #OpenAccess at
@Nature
@CNIC_CARDIO
#microbiome #CVD

[Didier Soulat @Tazoul]

The more I try to understand this (I don't...), the more I'm fascinated.
Supernovae evidence for foundational change to cosmological models https://t.co/49i28fhFSu

[News from Science @NewsfromScience]

Chimeric antigen receptor T-cell (CAR-T) therapy, already approved for certain blood cancers, is generating excitement in early tests against autoimmune diseases. #LongReads https://t.co/tlBuKAjEvV

[Didier Soulat @Tazoul]

@DamDeville Très intéressante. Cela donne quoi si vous passez les émissions en échelle linéaire au lieu de logarithmique. Cela casse le visuel? Mais cela serait peut-etre plus parlant?

[Didier Soulat @Tazoul]

@claudiasjv7 @UniFAU Welcome @UniFAU !

[Max Planck Institute for the Science of Light @MPI_Light]

It was a fabulous opening ceremony for the Max-Planck-Zentrum für Physik und Medizin!

Many thanks to all participants who made this day so special! 🙏

We are looking forward to the research at the MPZPM taking off! 💨

#Research #Physics #Medicine #Inspire #MPZPM @UniFAU

[Michael Okun @MichaelOkun]

Does the brain change during pregnancy? You bet it does. How about doing 26 MRI scans on a single person pre-conception to 2 years post-partum. WOW! Laura Pritschet and colleagues nailed it with their new paper in @NatureNeuro.
Key Points:
- The authors point out that pregnancy is a period of profound hormonal and physiological changes.
- The authors did something incredible by mapping neuroanatomical changes in an individual from preconception through two years postpartum.
- Boom! There were pronounced decreases in gray matter volume and cortical thickness.
- There were increases in white matter microstructural integrity, ventricle volume and cerebrospinal fluid.
- There were few regions untouched by the 'transition to motherhood.'
My take: This study shows us how a single brain in a single person can be a powerful resource when scanned serially over time. This method is hard to pull off, however what it has the potential to teach us about neuroscience is mind-blowing. Though this paper is only a single subject, the data provides a comprehensive map of the human brain across gestation. It will be interesting to add to the dataset, so we can understand changes across multiple persons and multiple conditions. The convergence of evidence is revealing that pregnancy as associated with dramatic neuroplasticity. How about a shout out to this 38-year-old woman who underwent 26 MRI scans along with blood draws from 3 weeks preconception through 2 years postpartum!
https://t.co/LEnPHzKCcl #pregnancy #brain @ndosenbach @andreashorn_ @EMiddlebrooksMD

[Max Planck Institute for the Science of Light @MPI_Light]

At the new Max-Planck-Zentrum für Physik und Medizin (MPZPM) in Erlangen, five Core Groups will conduct research to meet the most urgent medical challenges facing our society.

Get to know the group ›Tissue biomechanics‹ led by Prof Benoît Ladoux 👉 https://t.co/4jKD1yo1if

[Didier Soulat @Tazoul]

I'm sharing this because I was surprised by the intensity of the changes forecasted here. Living in Germany, I heard about the issue before... but the range!?

[François Valentin @Valen10Francois]

One good map = 100 articles

Here's the projected population growth in Germany, take a look at Saxony at Thuringia who just massively backed the far-right AFD

[Trends in Parasitology @TrendsParasitol]

Drs Christian Bogdan, Noor-A-Kasida Islam, David Barinberg @Tazoul Ulrike Schleicher & @BapluRai review the #immunomicrotope of #Leishmania control & #persistence. #Leishmaniasis #Immunity #Evasion #NOS2

https://t.co/jkShKMvT1o

[Didier Soulat @Tazoul]

I'm very grateful to Christian Bogdan and all other authors (esp. @BapluRai) for the opportunity to participate in this insightful review introducing the concept of "Immunomicrotope".
https://t.co/1X4On6aLcY

[SandoghdarLab @SandoghdarLab]

One more important step toward quantitative analysis of nanoparticle samples…

[Ricardo Grieshaber-Bouyer @grieshaber]

We are looking forward to hosting @DrOlivierBoyer from @FCEPAnTHER @univrouen @Inserm for an invited lecture @UniFAU tomorrow! @Focis_FCE @FOCISimmunology

[Didier Soulat @Tazoul]

Perplexity’s grand theft AI https://t.co/bGI0u78PkA via @Verge

[Didier Soulat @Tazoul]

@FR_Consulaire Comme pour les dernières législatives, impossible de voter en ligne.

[Le Gorafi @le_gorafi]

Le pays qui célébrait le Débarquement contre le fascisme il y a trois jours vote massivement pour le fascisme https://t.co/hHqdLcX13d

[Eric Topol @EricTopol]

A systematic review of airplane flights and Covid infections: duration of flight correlated with infection risk, long flights> 6 hours markedly increased risk (25X) and mask use blocked them
https://t.co/KIdLgKB1zV
h/t @linseymarr