New preprint out!
Timsim: a framework to simulate native #timsTOF dda-PASEF and dia-PASEF datasets with full ground-truth annotation, enabling precise benchmarking of #FDR and phosphosite localization errors in #proteomics and #immunopeptidomics workflows. (1/2)
Our benchmarks reveal inflated true FDR (3–5%) when modified peptidoforms are considered and highlight peak-matching errors in match-between-runs analyses.
Great collaboration with the labs of Andreas Hildebrandt and Mathias Wilhelm. (2/2)
Preprint: https://t.co/d2rUcyFxgc
The event was an incredible learning experience in #proteomics while reconnecting with old friends and making new ones in the community. Special thanks to #DGPF and @HUPO_org for supporting my journey with a travel grant. (2/3)
Thrilled to have shared our latest research on "MAETi: Mild Acid Elution in a Tip enables MS-based immunopeptidomics profiling from as low as 50,000 cells" at #HUPO2024 in Dresden! (1/3)
A new version 24 of the Human Protein Atlas resource has been released at the HUPO meeting in Dresden, Germany. The data is summarized in eight resources covering different aspects of human protein-coding genes in tissues, cells, cell lines and blood.
https://t.co/U18BHVMXYF
☹️Google Scholar is a great tool. But it doesn't show how papers are connected with each other.
😀Here's how to fast-track your literature review with a "visual search."
And export your papers to Zotero, Mendeley, or EndNote.
You can learn this workflow in 15 min:
Follow this excellent tutorial if you want to improve your DDA-PASEF acquisitions with Thunder-DDA-PASEF and ensure high-coverage immunopeptidomics analyses ⬇️
Huge congrats to @TenzerLab@DavidGomezZep and co-authors for this fantastic work recently published in @NatureComms! 👏
Job Alert 🌟 We are recruiting a postdoc in #lcms based #immunopeptidomics in our group @HITRONMainz - position is fully funded for two years. Check the job description and apply here:
https://t.co/bPBY11OfMT
Please RT!
Save the date! The 3rd HUPO-HIPP summer school. Université de Montréal, Canada August 14th to 16th 2024. @hupo_org#immunopeptidomics#HLA https://t.co/EJDHN13JHx
@Karl_Mechtler This is a critical and most likely not only theoretical issue. "Sample preparation blank/no cell" SCP samples can reveal unexpected effects.
‼️To all junior professors and senior postdocs #teammassspec: if you are doing cool stuff in MS, please apply for the prestigious Mattauch-Herzog award of the German Society for MS 🔽.
Please check here:
https://t.co/Zrd2ZCsZpM