Hot on the heels of our Circulator comes...
The Resonator!!! PSF-based excitation multiplexing and more! All in a compact and simple optical add-on. Very excited! https://t.co/ZsFCUoXI6l
It's finally out!
TL:DR We identified 3-mercaptopyruvate sulfurtransferase (MPST) as one of the key enzymes in generating and maintaining protein persulfides in cells! A short thread on the paper (1/n)
https://t.co/OWfTnT8ABQ
Fluorescentiemicroscopie levert niet alleen wetenschappelijke inzichten op, maar ook oogstrelende beelden 🤩🔬 de expo 'Shine On!' is nog tot het einde van de maand gratis te bezoeken in de Bib Tweebronnen @stadleuven https://t.co/WIeq1vx2Ul
Amazing talk by @LazarLab at the Shine On! symposium explaining the directionality of fluorescent protein absorption and emission! Real out of the box research on fluorescent proteins!
Slow folding and negative design are not specific to beta-barrels. Local structure frustration and slow folding also define protein secretability. Thanks to (twitter-less) Tassos and Lily for including us into this super interesting work! Also with @wim_vranken @structbiolbxl
Doing multicolor (single-molecule) imaging? Tired of waiting for each color?
Want simultaneous imaging with full field of view but without the multicamera hassle?
Take a look at our 'Circulator'! 🔥💪
https://t.co/MjflFNdSGl. Very excited so please RT! (1 of 5)
#microscopy
Just out of our lab! 📢😇
Marco Dalla Vecchia (@Marcodv93) and co-authors developed genetically encoded FRET biosensors based on the chemigenetic SNAP and HaloTag domains:
https://t.co/TmfJahjKQy
#FRET#biosensors#halo#snap
I'm happy to share our latest contribution and my first co-corresponding paper.
TLDR; We developed a method to parameterize fast events detected by nanopores.
https://t.co/HrkOjqleEl
@MagliaGiovanni@BiophysK@ResearchGbb
https://t.co/ObSP3rBgJV
Here Huang shows that it is possible to measure a single point mutation in a 65 kDa folded protein using a nanopore! And hemoglobin can be counted and identified directly from blood
https://t.co/neQaiXZ1WX
Here Roderick shows that nanopores can be used to quantify PTMs in proteins (in the form of a rhamnosylation reaction) using the nanopore peptide profiling method we recently developped
Looking for absolute quantification of cellular activities based on photochromic biosensors?
Check out our latest paper!
https://t.co/MniyCSYDkH
Big thanks to all collaborators including
@HofkensLab and @Campbell_FPs!
Really happy to have been part of this Perspective piece by Jose Losa and @HeinemannLab, with @CG_Martini. We'll be interested to hear what you all think, scientific twitter!