The Ott Lab

Melanie Ott's lab @GladstoneInst studying host-viral pathogen interactions. Tweets from lab members. Retweets are not endorsements.

[The Ott Lab @TheOttLab]

Interested in learning more about our lab? We have a shiny, new, up-to-date website where you can see everything that we're currently working on. Check it out! https://t.co/SzrOObRlt3

[Gladstone Institutes @GladstoneInst]

A team of Gladstone scientists—including Katie Pollard, Melanie Ott, Seth Shipman, and Sukrit Silas—will lead one of three new national centers dedicated to accelerating the development of phage therapy.

@TheOttLab
@seth_shipman

https://t.co/XqgRbhtsl7

[Gladstone Institutes @GladstoneInst]

🚨 NEW PUBLICATION 🚨 "Programmable kinetic barcoding for multiplexed RNA detection with Cas13a" in @natBME, with work from @TheOttLab.

https://t.co/7hXWF7tmGc

[Gladstone Institutes @GladstoneInst]

Melanie Ott and Nadia Roan are central to a groundbreaking effort to create the world’s first map of how HIV affects the immune system at a single-cell level.

@TheOttLab
@amfAR

https://t.co/Rag5XVZTqm

[Fletcher Lab @FletcherLab_UCB]

In our new work published in @natBME in collaboration with @TheOttLab and @Doudna_lab, we introduce "interfering" guide RNAs (igRNAs) for CRISPR-Cas13a that regulate enzyme activity after activation. Congratulations to all the authors!

https://t.co/d8k3x4hTt5

[The Ott Lab @TheOttLab]

We honor the life of J. Michael Bishop, whose groundbreaking discoveries helped transform our understanding of cancer and opened new paths for treatment. His legacy will continue to inspire generations of scientists and clinicians. Rest in peace.

[Gladstone Institutes @GladstoneInst]

From chronic treatment to true cure: Melanie Ott (@TheOttLab)
makes the case that controlling HIV isn’t the finish line—it’s just the beginning.

Read more: https://t.co/CXLMeFkfmn

[Gladstone Institutes @GladstoneInst]

Once a godsend, antiretroviral therapy is not what we should settle on. The time has come to finally cure HIV/AIDS.

Read more in this commentary from Melanie Ott (@TheOttLab)

https://t.co/CXLMeFkfmn

[Gladstone Institutes @GladstoneInst]

Excited about a future in STEM? Applications are open for Gladstone’s 2026 PUMAS Summer Internship Program!

PUMAS is a unique opportunity for community college students to gain real-world experience in biomedical research.

Learn more on our website ➡️ https://t.co/nkGGrcjPf2

[The Ott Lab @TheOttLab]

Tune in for our event on TikTok LIVE: “HIV Cure Lab Tour + Q&A"!
📆 Monday, December 1, 2025 at 10am PT

📍 Live on TikTok via @RaifDerrazi
🔗 Register: https://t.co/J4oLDoGT13

[Gladstone Institutes @GladstoneInst]

🚨 PUBLICATION🚨 "HIV-Induced T Cell Quiescence and the Origins of Viral Latency" in @NatImmunol

From the @TheOttLab

https://t.co/JsfApOwLhz

[Alex Sigal @sigallab]

Virologists need to reclaim the gain of function debate from politicians and set up streamlined international guidelines to work on viruses with pandemic potential. Read more in this @Nature opinion piece by @TheOttLab, @Virus_Immunity, and myself:

https://t.co/D1e6VCGbF0

[The Ott Lab @TheOttLab]

The Gladstone Institute of Virology has taken on a new name: the Gladstone Infectious Disease Institute. Check it out here: https://t.co/I1I3r5Y6FC

[The Ott Lab @TheOttLab]

Check out Dr. Melanie Ott's recent opinion piece on the SF Standard: https://t.co/Yxjceos7jH

[The Ott Lab @TheOttLab]

Congrats Fran!

[amfAR @amfAR]

Meet amfAR’s 2025 Mathilde Krim Fellows: Drs. Hastie, King, Ou & Zapatero Belinchon. As HIV research faces steep NIH cuts, amfAR is proud to back these bold young scientists and their innovative ideas. Learn more: https://t.co/7Rmjhn4A82

[amfAR @amfAR]

Thank you for supporting the next wave of HIV researchers.
Because of you, amfAR’s 2025 Mathilde Krim Fellows are advancing bold ideas that bring us closer to a cure. Hear why your support matters.

[The Ott Lab @TheOttLab]

Congratulations to Julia Prigann for being awarded the 2025 CFAR Excellence in Basic/Translational Science Award!
https://t.co/Uew4auq1PM

[The Ott Lab @TheOttLab]

We are delighted that we could help with this work. Check it out here: https://t.co/nl2aPBBgkt

[Gladstone Institutes @GladstoneInst]

Scientists from Gladstone and @UCSF have developed drug candidates that could prevent future coronavirus pandemics.

Read more about this recent study: https://t.co/igVEOyv0VE

@ucsfpharmacy
@UCSFMedicine
@ScienceAdvances
@TheOttLab
@KroganLab
@QBI_UCSF

[Gladstone Institutes @GladstoneInst]

Scientists from Gladstone and @UCSF has developed new antiviral drug candidates that show great promise against SARS-CoV-2, the virus that causes COVID-19, and may also be effective against other coronaviruses.

Read more: https://t.co/igVEOyv0VE

[Gladstone Institutes @GladstoneInst]

🚨 NEW PUBLICATION 🚨 "Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy"
@UCSF
@ucsfpharmacy
@UCSFMedicine
@ScienceAdvances
@TheOttLab
@KroganLab
@QBI_UCSF
https://t.co/CQdLqepSWQ