Wu Lab

We are the Ting Wu Lab, located in Boston at Harvard Medical School in the Department of Genetics.
Managed by WuLab members

[Eric Joyce @ericjoycelab]

🚨New preprint from the lab🚨
🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK.
https://t.co/KGTUAZqHyS

[Wu Lab @TingWu_Lab]

The lab had fun at the @HMSGenetics end of summer carnival! 🐰🐔🐤🦆🐑🐐

[Irene Farabella @iosonoirene]

Our lab is on the lookout for curious and creative PhD candidates as part of the @RNA_iit. Don't miss out - there's still time to apply! @semm_it @IITalk #compbio

[Single Molecule Localization Microscopy Symposium @SMLM_Symposium]

Last week, #SMLMS2024 started! Considering we had an earthquake hitting Portugal just days before, we can say it was definitely groundbreaking. Hope you all had an amazing meeting!
Looking forward to seeing you again at Bonn's #SMLMS2025 hosted by @UEndesfelder and @HeilemannLab

[Mario Del Rosario @_mariod]

our next talk features @JumanaAHA and her impressive work on chromosomal homolog interactions 🧬🔬 Jumana is also a new PI hiring, start applying now 😊 #SMLMS2024 @SMLM_Symposium

[Single Molecule Localization Microscopy Symposium @SMLM_Symposium]

WELCOME TO SMLMS2024🇵🇹 Happy to see so many shares and posts using the hashtag #SMLMS2024 Keep them coming!

[Laura Breimann @Laura_Breimann]

Our newest addition to lab (a fantastic technician) is super artsy, I love it! #FISH

[Laura Breimann @Laura_Breimann]

Fantastic work from @mpsmela1 showing fast induction of #meiosis from human iPSCs! Happy I could contribute a bit to the work!

[Personal Genetics Education & Dialogue (PGED) @pgEDorg]

✨We're launching a Community Spotlights series to highlight some of the amazing people we've connected with through our work. We're thrilled to feature @prof_dasgupta for the first spotlight! Learn about Shoumita's work & her upcoming book: https://t.co/iqHBqpx9LQ.✨

[Personal Genetics Education & Dialogue (PGED) @pgEDorg]

Join us to explore Genetics & Spirituality on May 22! Hosted by UNMC in Omaha + online. It’s been an honor working with Pastor Richard Randolph and co-organizers on this launch event for the Science and Spirituality Institute. Register to attend: https://t.co/A485IKgnyL.

[MSBDartmouth @MsbDartmouth]

Please join us in Kellogg 200 to hear the latest research from Dr. Ting Wu on Monday, May 20, 2024, at Noon. @GeiselMed @dartmouth @DartGRAD @MCBDartmouth @DartmouthNeuro @QBSdartmouth @DartmouthBCB @TingWu_Lab

[CNAG @cnag_eu]

🧬The Genome Organization & Nuclear Function Meeting (@cshlmeetings) kicks off today!

🧑‍🔬Our Structural Genomics Group Leader, @mamartirenom, is 1⃣ of the discussion leaders, presenting:

🗣️"Sex-determining 3D regulatory hubs revealed by genome spatial auto-correlation analysis"

[Wu Lab @TingWu_Lab]

Finally, we took a new lab picture with our newest members!

[Sandipan Brahma @BrahmaComplex]

It was such as treat to have @TingWu_Lab present at @UNMC_GCBA, hear fascinating stories about the evolution of discoveries about homolog-pairing, and exchange deeply thought-provoking ideas. Thanks for your time. We had so much fun!!

[Johannes Stein @jomo_stein]

Multiplexing with Exchange-PAINT can be also directly leveraged for tokPAINT as well as multi-omic cryosection protocols targeting proteins, DNA and RNA. [6/11]

[Personal Genetics Education & Dialogue (PGED) @pgEDorg]

Don't miss out on this important conversation! We hope you join us! Go to https://t.co/W1IqNkYhXB to register for free.

[Johannes Stein @jomo_stein]

Great news, this does not only work in fixed cells but also in ultrathin cryosections of tissues, as we show for tokPAINT imaging of Pol II within mouse tissues. [5/11]

[Jumana AlHaj Abed @JumanaAHA]

Looking forward to my first time giving a talk in front of a biophysics audience @BiophysicalSoc today.
Come to ballroom B at 9:00 to see how I use chromosome walking in super-res to understand homologous chromosome communication. #BPS2024

[Johannes Stein @jomo_stein]

Achieving sub-3 nm localization precisions, tokPAINT enables detection of Pol II down to level of single antibodies. Bonus: cryosections are openly accessible to probe diffusion, enhancing imager binding kinetics, e.g. for molecular counting via qPAINT. [4/11]

[Johannes Stein @jomo_stein]

Inspired by previous work (e.g., by @apombo1, @Eric_Betzig, @HeilemannLab) we adopted Tokuyasu cryosectioning, widely known from Immunogold EM, to enable nuclear tokPAINT imaging of Pol II using TIRF. [3/11]