Tofaris Lab

Molecular Neurodegeneration Research Group at @NDCNOxford based at @KavliOxford.

Researching Parkinson’s pathogenesis aiming to identify targets for therapies.

[George Tofaris @GeorgeTofaris]

Many congratulations to our talented #DPhil student
@Gordon_Lam97 @TofarisLab @KavliOxford @NDCNOxford who received an award from the Henry Lester Trust for his studies using iPSC-based models of #Parkinson's disease. Well done! Keep an eye out for his paper!

[Tofaris Lab @TofarisLab]

Thanks so much to @OxNeurosci for organising such a fantastic day for the neuroscience community last week at @UniofOxford!

Our Master’s student, Emilia Hogg, had the opportunity to present her project and engage with the community, a great experience all around 🧠✨
@NDCNOxford

[Tofaris Lab @TofarisLab]

"During my undergraduate degree, I developed an interest in the mechanisms underlying pathological brain ageing and was particularly drawn to understanding Parkinson’s disease.

🚣Outside of my studies, I enjoy rowing and ski instructing."

[Tofaris Lab @TofarisLab]

🎉We are happy to welcome Emilia Hogg for her Master's project.

@NDCNOxford @KavliOxford

"As part of my Master’s in Clinical and Therapeutic Neuroscience, I am joining the lab to study ⍺-synuclein aggregation and degradation.

[George Tofaris @GeorgeTofaris]

Many congratulations to @ShijunVictorYan who has transitioned from a very successful DPhil @TofarisLab @NDCNOxford @KavliOxford directly to Distinguished Investigator at Zhejiang University. An outstanding achievement. He is the 4th @TofarisLab alumnus to become Assistant Prof!

[Ana Aragón-González @AnaAragonG]

🇬🇧Great meeting organized by @SomosRAICEX, the network of associations of Spanish researchers abroad. We shared challenges, collaboration opportunities, and I had the opportunity to present my research titled “From Skin to Brain: Science to Understand Parkinson’s”
@ComunidadCeru

[Tofaris Lab @TofarisLab]

Wonderful talk by @sahooanis who presented our recently published Cell Reports Medicine paper on surface #EV alpha-synuclein as an early #Parkinson’s biomarker at @UKEVSocc Forum 2025🔬
🔗https://t.co/cOo2sz223l
@NDCNOxford @KavliOxford

[Francesca Magrinelli @FraMagrinelli]

Stunning talks by Prof. Maria Grazia Spillantini @SpillantiniLab @Cambridge_Uni and Prof. @GeorgeTofaris @TofarisLab @UniofOxford at the last Basal Ganglia Club meeting of the year. See you in 2026! @kailashbhatia @UCLIoN_DCMN @MDC_IoN_UCL @UCLBrainScience

[George Tofaris @GeorgeTofaris]

Delighted to share our latest @TofarisLab publication: Serum p-tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behaviour Disorder
https://t.co/tviSk7ojh1
#AnnalsofNeuro @ANA_journals @ShijunVictorYan @SahooAnis @NDCNOxford @KavliOxford

[Tofaris Lab @TofarisLab]

Thank you very much to @AgeUKOxon for helping to promote our call for participants for this exciting project led by Dr Rebecca Frake!

https://t.co/1nka5o6AzK

📩 Get in touch if you’d like to take part.
@NDCNOxford @KavliOxford

[Age UK Oxfordshire @AgeUKOxon]

🧠✨ Are you 80+ or know someone who is? The Nuffield Dept of Clinical Neurosciences, @TofarisLab @NDCNOxford, is running a ‘SuperAgers’ research study and looking for volunteers for a small focus group to help shape the research.

📧 Info: [email protected]

[Francesca Magrinelli @FraMagrinelli]

📢FLYER OUT
The next Queen Square Basal Ganglia Club Meeting will host Prof. Maria Grazia Spillantini from @Cambridge_Uni and Prof. @GeorgeTofaris from @UniofOxford.
🌍@UCLIoN, London
📅03/12/2025, 4PM
All welcome
Please🔁
@kailashbhatia @UCLIoN_DCMN @MDC_IoN_UCL @UCLBrainScience

[Theresita Joseph @tdjoseph21]

Fantastic presentation and discussion today by @GeorgeTofaris in Boston - excited to learn more about the latest developments in EV a-Synuclein research 🧠🔬

[George Tofaris @GeorgeTofaris]

Many congratulations to our talented #DPhil student @Gordon_Lam97 @TofarisLab @KavliOxford
@NDCNOxford who was awarded a Great Britain-China Education Trust scholarship for his mechanistic studies using iPSC-based models of #Parkinson's disease. Well done and very well deserved!

[Tofaris Lab @TofarisLab]

I am motivated to understand how glial cells coordinate to maintain neuronal health and how their dysfunction contributes to neurodegeneration.
Outside of the lab, I enjoy ballet, working out, going to art museums and musicals."
@NDCNOxford @KavliOxford

[Tofaris Lab @TofarisLab]

We welcome @MJKimSerena, to our group!
"For my DPhil project, I will study interactions between neurons, microglia and astrocytes in Parkinson’s using human stem cells.
At @UKDRI in UCL, I worked on how brain hyperactivity contributes to immune-driven synapse loss in AD.

[Tofaris Lab @TofarisLab]

🎉Huge congratulations to the @AlzResearchUK ‘Running Researchers’ team for raising nearly £6,000 for life-changing dementia research.

✨Special congratulations to our #DPhil @Gordon_Lam97 for his fantastic run in the @OxfordHalf! 🏃🏻‍♂️💪

@NDCNOxford
@KavliOxford

[Tofaris Lab @TofarisLab]

"I aim to work on a project on biomarkers, which might help us to improve the detection and understanding of diseases like Lewy Body dementia.
When I’m not working in the lab or the hospital, I enjoy classical singing, baking and spending time with my cat."
@KavliOxford

[Tofaris Lab @TofarisLab]

🥳We are very excited to welcome Dr Kilda Carpenter to our lab!
@NDCNOxford
"I’m Kilda, an Academic Clinical Fellow in Old Age Psychiatry. My research interests include neurodegenerative conditions, especially Lewy Body dementia, and visual hallucinations in older adults."

[George Tofaris @GeorgeTofaris]

This week we celebrated @_Suman_Dutta, who soon transitions to independence as Assistant Professor. He is the third member of @TofarisLab to achieve this milestone! A fantastic colleague and an outstanding scientist all around. Many congratulations Suman and all the best.

[George Tofaris @GeorgeTofaris]

We were awarded GOLD Laboratory Efficiency Assessment Framework (#LEAF) standard aiming to reduce carbon impact & promote sustainable lab practices. Well done to everyone @TofarisLab.
Special thanks to Andrew Castle who spearheaded this effort!