Tom Elliot

[email protected]

[Sky News @SkyNews]

Salmonella could be engineered to help fight bowel cancer after research found the bacteria stops the body's own immune cells attacking the disease.

🔗 Read more
https://t.co/0blIlBxn8G

[Rebecca Drummond @theRAD_lab]

We're hiring! 3year post-doc available in the lab on fungal adaptation to the host. Funded by @wellcometrust and working closely with @BECKS_182 team. Further details in link below, informal enquiries welcome!
https://t.co/OBGMDi74SM

[Evangelos Giampazolias @giampazolias]

Very excited to share our latest work, out today in @ScienceMagazine, on the serendipitous finding that vitamin D ☀️ regulates the gut microbiome to promote cancer immunity🦠 https://t.co/4XVuCoDUNa 🧵👇 @ReiseSousaLab @TheCrick

[Harriet @harriet_jg]

✨New preprint ✨

So pleased to share my first ever paper from @DrMicroMandroid’s lab at @IMIBirmingham. Here, we used multiplex imaging to show a correlation between H. pylori and invasion of gastric microbiota during gastric cancer development 🧫 https://t.co/xW3jrEVz8t

[Tom Elliot @TomAshEmElliot]

@harriet_jg @DrMicroMandroid @IMIBirmingham Congrats Harriet your RNAscope looks amazing!

[Rebecca Drummond @theRAD_lab]

Paper publication day! Our latest work online now in @NatureComms on the role of microglia in cryptococcal meningitis. Turns out these cells help the fungus more than us. Short thread of the main findings.
https://t.co/T93JYE5785

[Tom Elliot @TomAshEmElliot]

Here we discuss fundamental mechanisms of negative feedback control of TCR signalling, signatures of repsonse to checkpoint blockade, and how combination therapy strategies may overcome acquired resistance. (2/2)

[Tom Elliot @TomAshEmElliot]

Our review is out now in Essays in Biochemistry. T-cell response to checkpoint blockade immunotherapies: from fundamental mechanisms to treatment signatures. https://t.co/kCI4g7gmfz (1/2)
@BendingLab @DavidLeckyBio

[Kendle Maslowski Lab @MaslowskiLab]

NEW PREPRINT from the MasLab 😄. Great collaboration with @BendingLab and @SarahDimeloeLab for #Tcell dynamics and #immunometabolism. A beautiful example of #hostmicrobe dualism. Take a 👀 🧵👇🏻
https://t.co/PoDQJHTOus

[Tom Elliot @TomAshEmElliot]

@ScottPLand @FSampaziotis @britsocimm Congratulations!!!

[Sophie Rouvray @SophieRouvray]

Super excited to have my first poster at #bsi2022! I’m presenting my work on the role of Nr4a1 (Nur77) during T cell development and the control of thymic Treg niche size. Come say hi at poster #434😊

[Dr Lozan Sheriff @LozanSheriff]

Looking forward to present at #BSI22 my poster 466 this afternoon and discuss how combination therapy of anti-Lag3 and anti-PD-L1 can increase TCR signalling duration.

[Tom Elliot @TomAshEmElliot]

Come check out my poster 432 at #BSI22 today. Talking about regulation of TCR signalling. Also interested in discussing post doc work (graduating in about a year)

[Poppy Nathan @poppynathan]

Happy birthday to meeeeeeeeeee #BSI22

[Discovery Immunology Journal @discovimmunol]

💥 A new tool to assess rapid changes in TCR & BCR signalling dynamics #InVivo

@TomAshEmElliot & colleagues relay a new transgenic reporter of antigen receptor signalling that expresses Fluorescent Timer protein under the regulation of Nur77 👉https://t.co/mqtHiAXNjH 1/

[Tom Elliot @TomAshEmElliot]

CC @MaslowskiLab @LozanSheriff @DavidLeckyBio @GillianMackie_ @LisaScarfe2 @SophieRouvray Thanks for work on this project!

[Tom Elliot @TomAshEmElliot]

Glad to see this out! Thanks for support of @BendingLab and co-authors. In lymphocytes, expression of Nr4a family genes is controlled by antigen receptor signalling - making them great biomarkers of antigen detection. 1/

[Tom Elliot @TomAshEmElliot]

Differences in sensitivity between the two systems could well be due to much higher number of Nr4a1 transcripts over Nr4a3 in activated T cells. Please reach out to @BendingLab if you are interested in using Tempo mice! 12/