Trebak Lab

Professor of Pharmacology at Pitt. Investigator at the Vascular Medicine Institute. Interested in calcium signaling in physiology and disease.

[Trebak Lab @TrebakM]

Small Correction. Had to delete &retweet. In final form. Response to 3 attack papers by (now former) EiC+EBMs on the same issue of their own journal. If we were wrong, 1 peer-reviewed data-driven paper in an independent journal would have been enough.
https://t.co/wM2lVD9YFz

[David Yule @DavidYule64]

Check out our new paper. A great collaboration between the Yule, Orlandi and Groblewski labs:https://t.co/msE4Gf3AKK

[Science Signaling @scisignal]

Don’t miss this week’s new issue of #ScienceSignaling! New research shows how the loss of a calcium-sensing protein can exacerbate colorectal cancer growth, a preclinical study identifies dendritic scaffolds that shape the plasticity of synapses, and more. https://t.co/URFPoHJZ3b

[Science Signaling @scisignal]

Loss of the calcium sensor #STIM2, but not of STIM1, worsens #ColorectalCancer growth and metastasis by boosting calcium ion content in the endoplasmic reticulum, remodeling mitochondria, and rewiring transcriptional activity. @TrebakM @Trayambak_P https://t.co/DF0DZu5Jza

[Trebak Lab @TrebakM]

Great piece Manuel! Thank you!

[Manuel F. Navedo @mf_navedo]

🚨Editorial Alert🚨 Excited to share this editorial highlighting work from Magda Chrzanowska group in collab with @TrebakM Lab on the role of Rap1A in lung endothelium: https://t.co/XtHEQrDaaW

Collab with @Miguel_MartinAB & @MNCline @UCDavisHealth

https://t.co/t1o8shN254

[UC Davis Health @UCDavisHealth]

We're excited to share that @APSPhysiology named @mf_navedo the 2025 recipient of the Robert M. Berne Distinguished Lectureship! This award is presented annually by the society’s Cardiovascular Section to an established leader in cardiovascular research. https://t.co/7ZYO9ZgnUV

[Manuel F. Navedo @mf_navedo]

Paper alert!!! I am excited to share our recent work showing that phosphorylation of a single amino acid on the vascular Cav1.2 channel controls vascular reactivity & blood pressure in #hypertension. @ucdavis, @UCDavisHealth, @MCIPUCD, @UCDAVISPharmac1

https://t.co/wy1xTY9Uf6

[Trebak Lab @TrebakM]

Check out our new study in collaboration with the Chrzanowska lab showing that Rap1A regulates CRAC channels in endothelial cells as a mean to control NFAT activation and vascular inflammation!

https://t.co/OPkVyfBa1K

[Trebak Lab @TrebakM]

Congratulations on a fantastic lecture Martha!

[Martha Cyert @CyertMartha]

Thank you to #ECS2024 for establishing the Claude Klee memorial lecture and inviting me to deliver this keynote. Great way to celebrate Claude Klee’s legacy and talk about calcineurin!

[David Yule @DavidYule64]

Check out our new offering. Great collaboration with Serysheva lab. @Irina52948708

https://t.co/yEtMetTiKy

[Osama Harraz @OsamaHarraz]

I hope labs in Africa will take advantage of this fantastic opportunity! 🔬🌍

[Manuel F. Navedo @mf_navedo]

This is going to be a great meeting for vascular folks. Don’t suffer FOMO and register today!

[L. Fernando Santana 🇵🇷 @lfsantana68]

Check out our new collaboration with @RoseEDixon1 from @ucd_physiology in @PNAS (https://t.co/Z5QrzOA668). We observed two modalities of beat-to-beat ATP fluctuations in ventricular myocytes based on SR-mitochondrial coupling strength. (1/2)

[jECS @EuroCalcium]

Excited to announce the next #ECSwebinar on June 5th - 5 PM CET!🌟

We are looking forward to the talk of David Yule on modulation of IP3R regulation by Ca2+.

Find meeting link and updates on upcoming webinars here: https://t.co/pl0gAZxEaw

@DavidYule64

[Khaled Machaca @kmachaca]

Great opportunity for a young assistant professor in a vibrant research environment at WCMQ and in Qatar to perform cutting edge cell biology research with translational potential. https://t.co/b2Em9bQna9

[Khaled Machaca @kmachaca]

Check out this large collaborative effort re computational approach to drug design https://t.co/EoEB65hot3

[Trebak Lab @TrebakM]

https://t.co/UMRRSrVhgX

[Trebak Lab @TrebakM]

Congrats to @lfsantana68 for being named Distinguished Professor at UC-Davis, apparently the first Latino to receive this honor. Well deserved Fernando!

[Northwestern Feinberg School of Medicine @NUFeinbergMed]

Inflammation is a common feature of many diseases.

Murali Prakriya, PhD, discusses the evolution of this groundbreaking research in ion channels and his latest findings, which were published in @NatureComms, in this episode of our #BreakthroughsPodcast.

https://t.co/7ErDSv1tVE

[Khaled Machaca @kmachaca]

Contact sites between organelles are critical for cell physiology. Interestingly during cell division the contacts between the ER and mitochondria expand with implications on cellular energetics. https://t.co/2It7o7DYXY