Preventing Suicide by Professor Rob Poole, Professor Murad M. Khan and Professor Catherine A. Robinson
A succinct, evidence-based, and practical guide to suicide prevention from a multicultural and international standpoint.
📚 https://t.co/fSqMjUwp71
Predicting early clinical recovery in first-episode psychosis: development and external validation of a clinically interpretable multivariable model
#mentalhealth https://t.co/P2VF3sLjx9
🚨 Medical history rewritten: 19-year-old becomes the youngest person diagnosed with Alzheimer's.
In a medical first that has stunned the scientific community, doctors have diagnosed a 19-year-old with Alzheimer’s disease, marking the youngest confirmed case in history.
His symptoms began at just 17 with concentration issues and reading difficulties, eventually progressing to severe memory loss where his recall scores were over 80% lower than his peers.
Most strikingly, the teenager possessed no known genetic mutations or family history of the disease, defying the usual patterns found in early-onset cases which typically involve inherited triggers.
The diagnosis was confirmed through brain scans showing damage to the hippocampus and spinal fluid tests revealing classic Alzheimer’s biomarkers.
This case disrupts the traditional understanding of the disease as one reserved for the elderly or those with rare genetic predispositions. Researchers now believe that unknown biological pathways may trigger the condition, suggesting that Alzheimer’s can manifest much earlier than previously imagined. This discovery opens a challenging new frontier in neurology, demanding a re-evaluation of how the disease develops across different age groups.
Source: Jia, J., Zhang, Y., Shi, Z., Yin, R., Wang, S., & Ji, Y. A 19-Year-Old Patient with Probable Alzheimer's Disease. Journal of Alzheimer's Disease.
In this meta-analysis, patients with Bipolar Disorder who were treated with lithium had a 49% lower risk of developing dementia compared with patients with Bipolar Disorder who were not treated with lithium
@chrisaikenmd@CarlatPsych
https://t.co/1fvxVOMZD4
Efficacy and Acceptability of Licensed and Off‐Label Pharmacological Interventions for Insomnia in Patients With Severe Mental Illness: A Systematic Review and Meta‐Analysis of Randomised Trials
#mentalhealth https://t.co/ldDpJRdlXE
Camouflaging is when people on #autism spectrum mask symptoms or imitate normal interactions to avoid standing out.
It can work, but it's also a cause of distress, as new study finds:
https://t.co/yJR9OV7YR7
How do you manage this side effect of social skills training?
1/ Highlights from this crucially important paper:
About 7 out of 10 patients who get “evidence-based therapy” for depression are still depressed after treatment
Of the 3 that get well, about half would have gotten well without treatment
No significant differences between types of therapy (the “dodo bird verdict”)
“Third wave” therapies (eg, ACT) no better than plain old CBT, or any other form of treatment
From the paper: “Most patients do not respond or remit after therapy, and more effective treatments are clearly needed”
So… can someone please explain to me again why these treatments are routinely called “evidence-based therapy?”
Yet more evidence that haloperidol is not a sedative.
RCT to ⬇️ agitation in palliative care #delirium
1⃣haloperidol
2⃣lorazepam
3⃣halop + loraz
4⃣placebo
Haloperidol monotherapy was not more efficacious than placebo in reducing RASS.
https://t.co/ceA2P4Oj6y
Perception of depressive and suicide memes with different types of punchlines by persons with low or high suicide risk
#mentalhealth https://t.co/nkfZFTj436
Impact of maternal stress and COVID-19 exposure during pregnancy on offspring neurodevelopment: signature cohort 12 month follow-up
#mentalhealth https://t.co/IDlphdyGDV