CLEAR Trial

To investigate if hypertonic saline and carbocisteine improves outcomes for patients with bronchiectasis. Funded by NIHR HTA. All views are the
author(s) own.

[CLEAR Trial @TrialCLEAR]

Congratulations to @bronwenconnolly and all our friends at @MARCH_trial on completing recruitment of this important trial! 👏🍾

[MARCH @MARCH_trial]

WE'VE DONE IT! @MARCH_trial recruitment complete!

Thank you all!!

See below for live scenes from @bronwenconnolly's office...

[CLEAR Trial @TrialCLEAR]

Almost there @MARCH_trial ....16 to go now!⌛️
What an achievement this will be!👏

[CLEAR Trial @TrialCLEAR]

Congrats @OneillBon & team! 🥂

[iRehabTrial @iRehabTrial]

BREAKING NEWS 🚨🚨🚨

iRehab has hit recruitment target!!

Huge thank you to all sites for their hard work over the last 2 years of recruitment, we could not have done this without you💜

[Queen's University Belfast 🎓 @QUBelfast]

We are delighted to share the news that Professor Stuart Elborn CBE, Honorary Professor of Medicine at Queen's, has been awarded the 2024 British Thoracic Society Medal.

The BTS Medal is awarded annually to acknowledge the leadership of someone who has greatly contributed to respiratory medicine or science.

"I am delighted and humbled to receive the BTS medal. It is a testament to the amazing work of great teams of patients, clinicians, scientists and support colleagues who I have had the honor to work alongside in cystic fibrosis and bronchiectasis care and research.”

Congratulations, Professor Elborn!

Find out more: https://t.co/GA3gm1w0sw

#LoveQUB #LoveQUBResearch @MHLSQUB @BTSrespiratory

[CLEAR Trial @TrialCLEAR]

📢@TrialCLEAR Database Lock Completed ✅

Thanks in particular to site PIs for completing data review & sign-off in the past few months!

Have a great Christmas & happy new year to all!🥂

See you in 2025 for the exciting part ⌛️

[Frances Butler @DrFranButler]

What a lovely suprise in the post this morning! Thank you @TrialCLEAR It's been a privalge to be an adjudication panel member for the past 5 years. Some impressive stats there - 394 exacerbations adjudicated! #respisbest @TheACPRC @YorkResearch @YS_AHPs

[BE Clear with bronchiectasis @becleartoday]

Thank you!!! As someone living with bronchiectasis & a history of MAC infections, I anxiously await your findings. Our community wants to be proactive in ⬇️inflammation & infection & ⬇️ antibiotic use. Your trial will help better understand what preventive practices work.👏👏

[MARCH @MARCH_trial]

You've done it - fewer than 300 to go!!!! 🥳🥳🥳

Huge thanks from whole @MARCH_trial team, not least our glorious leaders @bronwenconnolly & @dfmcauley

[Fiona Copeland BEM @pcdmum]

Delighted to have been asked to attend the first Global PCD Advocacy Summit - lots of great ideas on how to collaborate and how to encourage people to take part in research. Even managed a swift pint in an English pub! @PCD_UK @PCDAustralia @PCDAustralia

[CLEAR Trial @TrialCLEAR]

🚨 Trial Follow-up Complete🚨

Thanks to all @TrialCLEAR teams involved, we today completed the last EVER study visit !🥂🍾

You have all contributed to provide much needed evidence for future treatments in the #Bronchiectasis community! 🫁😃

Publication incoming....⏳

[CLEAR Trial @TrialCLEAR]

Congratulations to the teams at @RBandH @BucksHealthcare who recently completed their final ever @TrialCLEAR study visit!😎

Every visit completed gets us closer to publishing this important research for the #Bronchiectasis community 🫁👏 @DonnaChabanne @mloebinger

[MARCH @MARCH_trial]

THANK YOU @crhcriticalcare @royalhospital @sarahbeavis10 for #1400!

Only 556 to go guys!

[CLEAR Trial @TrialCLEAR]

Roses are in season
Exacerbations are too
Don't forget to complete...
Your RSSQ 💘🌹🤓
@TrialCLEAR

[MARCH @MARCH_trial]

@bronwenconnolly has been shopping! 🍬

Send us a @MARCH_trial themed Halloween snap for your chance to win! 🎃📸

[CLEAR Trial @TrialCLEAR]

Always ahead of the carve 🎃 @MARCH_trial

[MARCH @MARCH_trial]

Calling all @MARCH_trial sites, it's competition time!

Post your spookiest MARCH themed photo for the chance to win some Halloween goodies for your team 📸 🎃

Winners will be announced 1st Nov

[CLEAR Trial @TrialCLEAR]

Thanks to our top recruiters to @TrialCLEAR . Enjoy! 😃

[Michelle Spence @michellespence_]

Thank you @TrialCLEAR for the amazing cookies! Enjoying a lovely treat to celebrate the end of recruitment 🍪

[CLEAR Trial @TrialCLEAR]

Thank you @PRCBlackpool
Enjoy the @OohAahCookies 🤗

[NIHR Blackpool CRDC @CRDCBlackpool]

Thank you for the lovely surprise! We have really enjoyed being a part of this study. Thank you @TrialCLEAR for allowing us to work on it 🍪

[CLEAR Trial @TrialCLEAR]

You are very welcome! Thanks again for the support @LungLab We love the photo!😀🍪

[Breathing Matters @Breathingmatter]

So happy to help identify patients for the important NIHR CLEAR study in #bronchiectasis - and very surprised and happy to receive cookies from the trial team for all our efforts #SoNiceToBeAppreciated 😊
@trialclear @LungLab

[bronwen connolly @bronwenconnolly]

Huge congratulations to @JudyBradley2910 and all in the @TrialCLEAR team for this fantastic achievement👏🥳

and to all of the patients who are part of this important @NIHRresearch trial to improve care and outcomes - you have done something amazing!

#bepartofresearch

[John Hurst @ProfHurst]

This is a huge achievement for the 🇬🇧 respiratory community, and people living with #bronchiectasis wherever they live.

The leadership from @TrialCLEAR has been incredible, and we are proud to have been a small part of CLEAR here @RoyalFreeNHS with @NIHRCRN_nthames.👏🏻