Cochrane review: CMV Ig did not reduce risk in SOT when used for CMV ppx. Wide variability in results for various studies though - may be 2/2 to heterogenicity of the precipitants across studies (tx type, immunosuppression) PMID: 17443573
CDC recommends for those that are vaccinated and then develop COVID-19 that it should not affect treatment decisions such as monoclonal antibodies https://t.co/Q2fJQ1a94W
Continuing 2020 IDSA NTM guidelines: for M. abscessus pulm disease, if macrolide sensitive rec 3 drug regimen, for macrolide resistance recommend 4 drug regimen
For pulm M. Kansaii tx- fixed 12 months of tx may be enough instead of 12 mo beyond culture conversion. Pooled data from 3 studies only found recurrence rate of ~ 5%.
https://t.co/AuZHL4t5T5
Younger tx recipient age associated with increased rates of rejection: thought to be 2/2 to decreased med adherence, T cell changes that come with aging
https://t.co/pLevAjTTQx
IDSA currently rec daily tx rather than TIW tx for cavitary MAC as TIW tx has been associated with lower than expected sputum conversion rates
https://t.co/cvu5xpTUsi