UCLA Broad Stem Cell

Supporting innovation, excellence and the highest ethical standards focused on taking stem cell discoveries from the lab to the patient. (RT≠endorsement)

[G.O. Discovery Lab @golabnow]

Our director, Dr. Sanaz Memarzadeh, will be giving a UCLA Health Jonsson Comprehensive Cancer Center Research Seminar discussing the current prospects in Gynecologic Oncology research as the field advances and expands to meet the clinical need.
Please see the flyer for details.

[UCLA @UCLA]

At UCLA, Dr. David Nathanson is designing new therapies that tackle glioblastoma’s unique tumor biology, aiming to overcome long-standing treatment challenges. https://t.co/VgAplSpWY8

[UCLA Broad Stem Cell @UCLAstemcell]

By day, Dr. Anthony Aldave advances gene therapy for inherited corneal disorders. After hours, he’s spinning EDM.

Learn about the @UCLASteinEye surgeon-scientist’s path to ophthalmology, global training work and mission to restore sight: https://t.co/jLYutPQaX3

[UCLA Broad Stem Cell @UCLAstemcell]

Congratulations to Dr. Aparna Bhaduri @BhaduriLab for receiving the 2026 Pershing Square Sohn Cancer Prize, a national award recognizing innovative early-career scientists pursuing bold approaches to cancer research! 🎉

🔗 https://t.co/G2kFdCyPR7

#ResearchPowersProgress

[UCLA Broad Stem Cell @UCLAstemcell]

Meet Dr. Anthony Aldave, a corneal surgeon @UCLASteinEye & #GeneTherapy pioneer working to restore sight for people with inherited corneal disorders.

Learn about his path to ophthalmology, global surgical training work and after-hours life as a DJ: https://t.co/jLYutPQaX3

[UCLA Broad Stem Cell @UCLAstemcell]

Don't miss Xiaowei Zhuang, Ph.D. of @Harvard University present, "Spatially Resolved Single-Cell Genomics & Functional Genomics," on Friday, May 8 at 12PM PT via Zoom: https://t.co/rIcpgGMD3V

@UCLAHealth

[UCLA Neuroscience Theme @UCLANeuroTheme]

Aging biology is moving fast. New work from @dgsomucla from @ACovarrubiasPhD highlights how “zombie” immune cells (senescent macrophages) in the liver build up with age and drive chronic inflammation. A powerful example of how training, discovery & collaboration are advancing our understanding of aging—and pointing toward new therapies.
https://t.co/uI4ItGeRZC

[Pelage Pharmaceuticals @PelagePharma]

Hair loss treatments haven’t meaningfully changed in decades. Pelage was built to change that.

We're advancing PP405, a topical therapy designed to reactivate dormant hair follicle stem cells to restore hair growth, with plans to initiate late-stage trials later this year. Read our full story below. https://t.co/LhTmPAl1t0

[UCLA Broad Stem Cell @UCLAstemcell]

For the first time, UCLA scientists @LTULab have mapped how Down syndrome reshapes the human brain before birth — uncovering surprising shifts in neuron development that may explain differences in brain size and cognition.
Read more ➡️https://t.co/wTZCXfavhk #BrainDevelopment

[UCLA Broad Stem Cell @UCLAstemcell]

A clinical trial for sickle cell disease that UCLA's @Kohn_Lab led over nearly a decade yields hard-won insights — and a roadmap for better clinical trial design for blood diseases.

Read more ➡️ https://t.co/gfsP5dbSb6

#ResearchPowersProgress #SickleCellDisease #GeneTherapy

[G.O. Discovery Lab @golabnow]

In collaboration with Dr. Jasmine Zhou and an incredible team of UCLA scientists, our director has published in the Proceedings of the National Academy of Sciences a new low-cost blood test to detect and monitor many diseases including ovarian cancer.
https://t.co/90o5EP5p3k

[UCLA Broad Stem Cell @UCLAstemcell]

About 1 in 3 Angelenos has fatty liver disease. @UCLA scientists may have just found a new way to treat it by targeting dysfunctional immune cells dubbed "zombie cells." 🧟🧫

#ResearchPowersProgress
@ACovarrubiasPhD

https://t.co/gkbFAJQ3zX

[Nature Aging @NatureAging]

Online now!✨RESEARCH: Salladay-Perez and colleagues interrogate whether macrophages can really undergo senescence, and characterize a p21+Trem2+ senescent macrophage population functionally implicated in inflammaging and liver disease @ACovarrubiasPhD https://t.co/19DfqeYY3g

[UCLA @UCLA]

ICYMI: FDA approval of a new gene therapy marks a major advance in treating a rare and life-threatening immune disorder in children. https://t.co/GNVkoQ2L6n

[UCLA @UCLA]

The FDA has approved a gene therapy developed at UCLA for a rare immune disorder, with clinical trial patients showing restored immune function. https://t.co/GJVvd261lA

[UCLA Broad Stem Cell @UCLAstemcell]

Read more: https://t.co/ZB3snPiiwG
#StemCells #RareDisease

[UCLA Broad Stem Cell @UCLAstemcell]

All 3 Langenhop kids were born with a rare, often-fatal immune disorder called LAD-I. After joining a UCLA #GeneTherapy trial, they're now "normal, happy kids" with functional immune systems.
Their trial participation helped make last week’s FDA accelerated approval possible.
💙

[The Kohn Lab UCLA @Kohn_Lab]

In collaboration with @RocketPharma , we celebrate the first FDA-approved gene therapy supported by @CIRMnews and CA taxpayer funding. #raredisease matters.

[STAT @statnews]

The FDA approved a gene therapy for severe leukocyte adhesion deficiency type 1 (LAD-1), an ultra-rare disease that leaves children vulnerable to life-threatening infections. https://t.co/iEWI6fFpKb

[UCLA Broad Stem Cell @UCLAstemcell]

How does the FDA-approved LAD-I gene therapy work?

Doctors take the patient's OWN stem cells, add a healthy copy of the mutated gene, and return them.

No donor needed. No transplant rejection risk. All 9 trial patients: restored immune systems.

🔗 https://t.co/gDPLIrKPwX