Oxygen & Muscle Metabolism Lab

PI: Gwenael Layec

Specialize in 31P-MRS, Respirometry, Doppler Ultrasound to investigate aging and chronic disease

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

We're hitting the ground running! Special thanks to the @UmassKin Muscle Biology Lab for letting us collaborate with them on their CHAMP study! @UMassSPHHS @UMassIALS #mitochondria #SlowMoMonday

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

🚨 New Publication! 🚨

We show that cigarette smoke directly inhibits mitochondrial electron convergence and adenine transfer via ANT. Great work by @decker_st!

https://t.co/1NLdTCFVXz

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

🚨 New lab publication! 🚨

[Stephen Decker @decker_st]

New publication! Effects of cigarette smoke on in situ mitochondrial substrate oxidation of slow- and fast-twitch skeletal muscles.

The first (1/3) publication of my dissertation!

PubMed: https://t.co/0Zfspg0TIr
Life Sciences: https://t.co/ITfoiGpHHA

1/n

[Stephen Decker @decker_st]

New publication! Effects of cigarette smoke on in situ mitochondrial substrate oxidation of slow- and fast-twitch skeletal muscles.

The first (1/3) publication of my dissertation!

PubMed: https://t.co/0Zfspg0TIr
Life Sciences: https://t.co/ITfoiGpHHA

1/n

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

Free article text!

🔗 https://t.co/ph73TJ8mNf

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

New publication! Exciting news to close out 2022 and welcome 2023!

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

New publication! Exciting news to close out 2022 and welcome 2023!

[Stephen Decker @decker_st]

We finished the year on a great note! New publication in Free Rad Biol & Med on how the receptor for AGEs mediates muscle dysfunction caused by cigarette smoke

Manuscript 👉https://t.co/KWUr85upOd

1/n

[Stephen Decker @decker_st]

Article accepted in Free Rad Biol & Med. More details to come soon. Merry Christmas to us!

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

New year, new experiments, same wonderful undergraduate assistants! We're very happy to have these helping hands back and eager to start our new and ongoing projects!

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

https://t.co/p7tQGsU1lC

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

Check out our latest publication in @japplphysiol, a collaboration with the University of Nebraska!

"Effects of passive and active leg movements to interrupt sitting in mild hypercapnia on cardiovascular function in healthy adults" | Journal of Applied Physiology

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

Check out our latest publication in @japplphysiol!

"From heart to muscle: Pathophysiological mechanisms underlying long-term physical sequelae from SARS-CoV-2 infection" | Journal of Applied Physiology https://t.co/RuomaMJ5E5

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

Running some microdialysis experiments this morning! @UMassIALS @UmassKin

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

Back in the lab again! Pilot testing our new heat therapy project! Get in contact with us for more details

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

Our visiting student from Italy, Gaia, is running great simultaneous H2O2 & respirometry pilot experiments in permeabilized cardiac muscle from mice! #BravaBravaBrava
@UmassKin @UMassIALS

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

We're recruiting! We're looking for adults for several research studies involving how muscle and blood delivery changes with age. For more information: https://t.co/gDdeJsFX2D

@UmassKin @UMassIALS @UMassSPHHS

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

We're in the final stages of getting our plantar flexion ergometer fully running. We will blood flow using Doppler Ultrasound during small muscle mass exercise! Also showing some spirit by wearing a nature-related shirt on #WildWednesday
@UMassIALS @UmassKin @UMassSPHHS

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

@UMassIALS @UMassAmherst @UmassKin @UMassSPHHS Running protocols on the Oroboros O2K Oxygraph #mitochondria

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

Doppler Ultrasound practice for our assessment of vascular function! We're getting ready for our upcoming studies! @UmassKin @UMassSPHHS @UMassAmherst @UMassIALS

[Oxygen & Muscle Metabolism Lab @UmassO2MLab]

We're so excited to be up and running! Check back soon for updates on upcoming studies and events!