Our paper just got published in royal society open biology🥳 In this article we show that cell wall-deficiency provides a reversible defense mechanism against phage attack! So proud that our tomogram is featured on the cover as well 😊https://t.co/1vmtcVblxG
Shared evolutionary roots for viral defense. @DaanFvdBerg@AnaRitaMCosta & Esser @StanBrouns discover bacterial homologs of eukaryotic antiviral defenses and demonstrate the anti-phage activity for six previously uncharacterized systems https://t.co/Aru2APiDsj
Excited to share our latest paper on new Eukaryotic-like bacteriophage defense systems. What great joint project by @DaanFvdBerg, @AnaRitaMCosta and Jelger Esser combining the power of bioinformatics and experiments.
https://t.co/xHEGbGQr87
🚨Super excited to share our pre-print describing how we used genomics to discover a family of anti-phage lanthipeptides from Actinobacteria 🦠
This marks a significant expansion in the number of bacterial natural products involved in chemical defense.
A thread 👇: @MDMlab_Paris
Clinical strains of Pseudomonas aeruginosa have accumulated phage defense systems in their genome matching their broad resistance to diverse phage families.
Great work by Rita, Daan and Jelger. @AnaRitaMCosta, @DaanFvdBerg
https://t.co/0b4w4mC8a4
As result of a public outreach with @SPP2330, engaging with local schools, we here present five novel Streptomyces phages infecting S. griseus, S. olivaceus and S. venezuelae.
May the phage be with you.
@dfg_public, @fz_juelich, @HHU_de
https://t.co/lXYNuD9wS4
So proud of my bachelor students @VeravanNeer and @AnnabelKempff, who described two new phage species in our paper that got published today!! 🎊👏
https://t.co/VeHZhx1otk
I am excited to share this work with you! We show that conidia (asexual spores) accumulate trehalose and mannitol during the spore maturation process. Conidia lacking these compatible solutes are extremely heat sensitive (16 orders of magnitude!!). (1/6)
https://t.co/8zP5N9r7Sl
🎙️ We introduce PHAGEBITES,
a new format with short interviews featuring PhD students and early-stage researchers, sharing their groundbreaking work!
In this episode, meet @VeroniqueO5 from Leiden University.
We have an open PhD position in the lab focusing on "Bacterial antiviral immunity" - looking forward to welcome more phage enthusiasts in our group!
@SPP2330 , @fz_juelich , @HHU_de
Feel free to contact me via email, in case you have any questions.
https://t.co/QOlQAHtkIe
Really glad to finally share my 1st baby from my post-doc 🥲
@AudeBer and I have been obsessed with viperins for a while, so we decided to trace their incredible story, from LUCA to #asgard#archaea, to #eukaryotes.
Even more fun: we did it in colab with my dear friend @fabaiwu
Happy to share our new preprint!
We used viperins🐍, to understand the conservation and diversification of immune genes across domains of life.
A deep dive in the evolutionary history of immune genes shared by prokaryotes and eukaryotes!
https://t.co/6iKcEEbfee
Here it is the best #phage therapy I ever read!
A monumental achievement by @PaulPirnay et al.
100 PT cases w/clinical improvement in 77% difficult-to-treat infections. The big conclusion "phages make antibiotics great again!"
Happy to contribute!💯
https://t.co/TsfRk3hYeP
Could not resist.
Making that figure in 2019, I thought the newly uncovered diversity of antiphage systems was already incredible.
We now know it was just the tip of the iceberg. I hope our new review will help people dive into this wonderful field.
https://t.co/bH3oGGzzLR.
So many novel antiphage systems out there! Hard to keep up with the pace of discoveries? We reviewed for @NatureRevMicro the highly diverse antiphage defence systems of bacteria; from molecular mechanisms to evolutionary drivers of such diversity.
https://t.co/eBdGmcRCBz