Vignali Lab

Immune regulation, regulatory T cells, inhibitory receptors, LAG3, Nrp1, IL35, cancer immunology, autoimmunity, TCR signaling

[Vignali Lab @Vignali_Lab]

Excited to share that I have been named the next Chair of the Department of Immunology at Pitt! We have a fantastic department and immunology community here and I’m honored to have the opportunity to help it grow!

[Science Immunology @SciImmunology]

Two new studies present insights into regulatory T cells located in tumors associated with head and neck squamous cell carcinomas and non-small cell #LungCancer.

By @Vignali_Lab: https://t.co/9NvZsHcapW
By @SmithImmunology: https://t.co/quwGFQoy3N

[Vignali Lab @Vignali_Lab]

This work is co-published with a complimentary study from @SmithImmunology and @dpardol1 groups, check out their exciting findings in detail at @SciImmunology!

[Vignali Lab @Vignali_Lab]

Regulatory T cells are phenotypically and functionally heterogenous in the TME, but what are the transcriptional networks of functionally suppressive Tregs in the TME?

Our latest work from the lab and first-author @Feng_Shan_ is out now at @SciImmunology! https://t.co/VipvrWy6Q2

[Vignali Lab @Vignali_Lab]

We are indented to members of the @VignaliLab for their help and advice, and colleagues in @UPMCHillmanCC and the Pitt Immunology Department. We are especially grateful to @TakisBenosLab, @BcellBruno, @RobertFerrisMD and all our collaborators for their contributions to this study

[Vignali Lab @Vignali_Lab]

See this link for more details and registration: https://t.co/TqP8khKLa6 2/2

[Vignali Lab @Vignali_Lab]

I'm excited to be co-organizing the next FASEB Autoimmunity meeting with @montserrat!  We have an amazing speaker line up, and these meetings always include fantastic presentations, and outstanding participation and discussion (and are a lot of fun!). Please join us! 1/2

[Vignali Lab @Vignali_Lab]

Tagging @OnkarSayali!

[Vignali Lab @Vignali_Lab]

Fantastic collaboration with @oesterreichs (co-senior author) and the entire team! Kudos to first author Sayali Onkar! @UPMCHillmanCC @Pitt_PMI

[Vignali Lab @Vignali_Lab]

Amazing collaborative effort and an honor (and fun) to work with @oesterreichs! And kudos to @OnkarSayali

[Dr. Steffi Oesterreich @oesterreichs]

Finally brave enough to enter area of immune-oncology-thanks to @Vignali_Lab🙏 Proud to share @NatureCancer paper on immune landscape in ER+ #breastcancer with focus on #lobular https://t.co/DwDQllS2a6 @UPMCHillmanCC @MageeWomens #lobmob @Adrianvlee @BCRFcure @SusanGKomen #bcsm

[Vignali Lab @Vignali_Lab]

Excited to share our latest paper in @NatImmunol entitled "IFNγ-induction of TH1-like regulatory T cells controls antiviral responses". Kudos to first author @AngelaGocher! @UPMCHillmanCC https://t.co/ogAMy0KpMv