Abandoned by wolves and raised by my parents, which accounts for my unusual perspective. I later wandered into science, where oddball ideas are tolerated.
Shouldn't post before my first espresso has jump-started my brain. Great collaborative project on the analysis of hyper-thermostable nanotubes whose surprising existence was first noticed by researchers at the University of Regensburg over 40 years ago. @EmoryChem
Exciting opportunity to join the University of Bristol as a BBSRC-funded Research Associate (4 years) working between us and @MarkDodding's lab. The post is on designing de novo peptides and proteins using both rational design and computational design and protein biochemistry.
@Tian_Yu1 Is that more or less cynical? I need to know the answer for myself. Seems that after Covid, I am more busy and more cynical, still working a lot of hours.
Donor Strand Complementation and Calcium Ion Coordination Drive the Chaperone-free Polymerization of Archaeal Cannulae https://t.co/1NKKP7hFqj
Happy that the preprint is now published. Great collaboration with fantastic colleagues. @conticellolab@EmoryChem
Please retweet!📢📢
We are looking to appoint a BBSRC-funded post-doctoral research associate to work in the area of de novo enzyme design with alpha-helical barrels using computational design, protein biochemistry, and directed evolution. More details below
Mono-pilus (found in both rich and poor media) conforms to canonical archaeal T4P structures where all subunits are equivalent, whereas in the other filament, the tri-pilus (only found in poor media), its outer domain flips almost 180° and trimerizes on the pilus surface.
Super cool use of #AlphaFold from the world famous @zhangf lab to help them develop a novel molecular syringe that could act as a new type of drug delivery system that could potentially target things like cancer cells!
https://t.co/pLE6SMRUx4
Check out our latest paper on @ACSSynBio about designing phosphorylation-responsive coiled coil assemblies. Many congrats to Harry and co! Read it here: https://t.co/B2UqYZfbYl