Thrilled to share our paper now out @NatureBiotech! High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
https://t.co/ceN9IluPuP
Excited to announce our study (w/ @RukmanThota & @MaxKrummel) published today @Nature:
Macrophages “hold our living identities” by taking tiny bites from living cells and presenting this information to CD8 T cells.
https://t.co/9XENtFrB4h
#immunology#cellbiology@immunox@ucsf
I'm honored to be among this year's @PDSoros Fellows! Check out the new cohort and all they've accomplished: https://t.co/8vBwD49cqH
Immensely grateful to @MaxKrummel, Alex Marson, @brshy, Julie Zikherman and many many more mentors who took a chance on me early in my training!
Today, we announced the 2026 Fellows—we hope you will read their incredible stories and learn about their work! Selected from 3,000+ applications, it was the most competitive year in our history.
https://t.co/kwdjVqcrXw
Excited to present the first major work after starting our lab at Stanford and the Arc this year: CRISPR-All, a unified genetic perturbation language for programming any major type of genetic perturbation simultaneously, in any combination, at genome scale, in human cells.
🚨Excited to share our latest work, now out in @NatureBiotech ! We introduce SEED-Selection, a powerful method that enables high-efficiency enrichment of T cells edited at multiple loci in a single step 🧵👇
🔗 https://t.co/5Dh4hQIfDn
Excited to share this new piece!
From taking art classes together back in grade school and visiting colleges together in high school to now being co-first authors, I'm looking forward to continue working and learning with @rishabrama in our future training and careers!
New research in mice indicates that #MastCells secrete an essential metabolite in Peyer’s patches needed for the production of for intestinal #immunoglobulin A. https://t.co/6mSnwD987k #IgA@MarcoDegiov89@UCSF
Intestinal IgA production depends on GPR35-expressing cDC2 positioning guided by mast cells within Peyer’s patches @MarcoDegiov89@jason_cyster@SciImmunology
https://t.co/EtJ989joSh
First paper from my time in @UCSF_MSTP is out today @SciImmunology! Had a blast learning from and working with @MarcoDegiov89 and the whole Cyster Lab @UCSF -- looking forward to seeing how the De Giovanni Lab continues this work!
🚨 New study for the lab!
We developed SEED selection, a method to purify KnockIns at multiple loci in a single step. Better, It takes no space in the donor template, can be easily multiplexed and its all through negative selection!
👏👏 @ChrisRChang
https://t.co/tWaIqHmZp6
Zikherman and colleagues describe a new mechanism by which B cells recognize virus-like antigen display as a stand-alone danger signal that does not rely exclusively on avidity and BCR cross-linking. Read it here: https://t.co/lWIqkX7lHZ
https://t.co/hszUKyojUZ
I am so glad someone finally published on the mechanism by which high valency antigens induce better B cell responses than soluble ones
https://t.co/OX5Hor9lWG
Great to see this published and thankful to have played a small part in this story during my time with @MarsonLab! Enjoyed working with my previous roommate, Dan, to develop ideas together -- Excited to see how this new tech impacts the genome engineering space!!
I’m excited to share our report - out now in @natBME - of a new approach to CRISPR delivery that is poised to transform the way engineered T cell therapies are manufactured. Visit https://t.co/UmTBpRE8jE for “how to” details. It’s threadin’ time! (1/11) https://t.co/MujT9iue56
Authored by Andrew G. Soerens et al, we show that #Tcells are capable of proliferating in response to iterative stimulation for over 10yrs! And produce enough progeny to occupy a volume 30,000x the Earth's volume! @Nature https://t.co/jPfmX2Ilrq